Antimicrobial activities of twenty lysine-peptoid hybrids against clinically relevant bacteria and fungi

Chemotherapy

Volumn 54, Issue 2, 2008, Pages 152-156

  Ryge, Trine S ^a   Frimodt Møller, Niels ^b   Hansen, Paul R ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b STATENS SERUM INSTITUT   (Denmark)

Author keywords

Antibacterial activity; Antimicrobial agents; Candida albicans; Lysine peptoid hybrids; Methicillin resistant Staphylococcus aureus; Minimal inhibitory concentration

Indexed keywords

LYSINE DERIVATIVE; N (1 NAPHTHALENEMETHYL)GLYCYL N (4 METHYLBENZYL)GLYCYL N (1 NAPHTHALENEMETHYL)GLYCYL [N (BUTYL)GLYCYL]LYSYLLYSYLLYSYLLYSINAMIDE; PEPTOID; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; DRUG STRUCTURE; ENTEROCOCCUS FAECIUM; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS;

ANTI-INFECTIVE AGENTS; BACTERIA; DRUG RESISTANCE, MICROBIAL; FUNGI; HUMANS; LYSINE; MICROBIAL SENSITIVITY TESTS; PEPTOIDS;

EID: 41349103509     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000119707     Document Type: Article

References (19)

1. Lohner K, Staudegger E: Are we on the threshold of the post-antibiotic era? In Lohner K (ed): Development of Novel Antimicrobial Agents: Emerging Strategies. Wymondham, Horizon Scientific Press, 2001, pp 1-15.
2. Barrett JF: MRSA: status and prospects for therapy? An evaluation of key papers on the topic of MRSA and antibiotic resistance. Expert Opin Ther Targets 2004;8:515-519.
3. Hsueh P-R, Lau Y-J, Chuang Y-C, Wan J-H, Huang W-K, Shyr J-M, Yan J-J, Yu K-W, Wu J-J, Ko W-C, Yang Y-C, Liu Y-C, Teng L-J, Liu C-Y, Luh K-T: Antifungal susceptibilities of clinical isolates of Candida species, Cryptococcus neoformans, and Aspergillus species from Taiwan: surveillance of multicenter antimicrobial resistance in Taiwan program data from 2003. Antimicrob Agents Chemother 2005;49:512-517.
4. Pfaller MA, Diekema DJ: Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus. J Clin Microbiol 2004;42:4419-4431.
5. Hancock REW, Sahl H-G: Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol 2006;24:1551-1557.
6. Mygind PH, Fischer RL, Schnorr K, Hansen MT, Sönksen CP, Ludvigsen S, Raventós D, Buskov S, Christensen B, De Maria L, Taboureau O, Yaver D, Elvig-Jørgensen SG, Sørensen MV, Christensen BE, Kjærulff S, Frimodt-Moller N, Lehrer RI, Zasloff M, Kristensen H-H: Plectasin: a peptide antibiotic with therapeutic potential from a saprophytic fungus. Nature 2005;43:975-980.
7. Robinson WE, McDougall B, Tran D, Selsted ME: Anti-HIV-1 activity of indolicidin, an antimicrobial peptide from neutrophils. J Leukoc Biol 1998;63:94-100.
8. Ifrah D, Doisy X, Ryge TS, Hansen PR: Structure-activity relationship study of anoplin. J Pept Sci 2005;11:113-121.
9. Patch JA, Kirshenbaum K, Seurynck S, Zuckermann R, Barron AE: Versatile oligo (N-substituted) glycines: the many roles of peptoids in drug discovery; in Nielsen PE (ed): Pseudo-Peptides in Drug Development. Weinheim, Wiley-VCH, 2004.
10. Ryge TS, Hansen PR: Novel lysine-peptoid hybrids with antibacterial properties. J Pept Sci 2005;11:727-734.
11. Steinberg DA, Hurst MA, Fujii CA, Kung AHC, Ho JF, Cheng FC, Loury DJ, Fiddes JC: Protegrin-1: a broad-spectrum, rapidly microbicidal, peptide with in vivo activity. Antimicrob Agents Chemother 1997;41:1738-1742.
12. Matsuzaki K: Magainins as paradigm for the mode of action of pore forming polypeptides. Biochim Biophys Acta 1998:1376;391-400.
13. Zasloff M: Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci USA 1987;84:5449.
14. Ericksen B, Wu Z, Lu W, Lehrer RI: Antibacterial activity and specificity of the six human α-defensins. Antimicrob Agents Chemother 2005;49:269-275.
15. Selsted ME, Novotny MJ, Morris WL, Tang YQ, Smith W, Cullor JS: Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils. J Biol Chem 1992;267:4292-4295.
16. Goodson B, Ehrhardt A, Ng S, Nuss J, Johnson K, Giedlin M, Yamamoto R, Moos WH, Krebber A, Ladner M, Giacona MB, Vitt C, Winter J: Characterization of novel antimicrobial peptoids. Antimicrob Agents Chemother 1999;43:1429-1434.
17. Kundu B, Srinavasan T, Kesarwani AP, Kavishwar A, Raghuwanshi SK, Batra S, Shukla PK: Identification of novel antifungal nonapeptides through the Screening of combinatorial peptide libraries based on a hexapeptide motif. Bioorg Med Chem Lett 2002;12:1473-1476.
18. Huygens F, O'Sullivan JF, van Rensburg CEJ: Antimicrobial activities of seven novel tetramethylpiperidine-substituted phenazines against multiple-drug-resistant Gram-positive bacteria. Chemotherapy 2005;51:263-267.
19. Ates-Alagoz Z, Yildiz S, Buyukbingol E: Antimicrobial activities of some tetrahydronaphthalene-benzimidazole derivatives. Chemotherapy 2007;53:110-113.