Increased retinal toxicity of intravitreal tissue plasminogen activator in a central retinal vein occlusion model

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 246, Issue 4, 2008, Pages 509-514

  Yamamoto, Takuhiro ^a   Kamei, Motohiro ^a   Kunavisarut, Paradee ^a   Suzuki, Mihoko ^a   Tano, Yasuo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Central retinal vein occlusion (CRVO); Ischemia; Retinal toxicity; Tissue plasminogen activator (tPA)

Indexed keywords

ALTEPLASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CENTRAL RETINA VEIN OCCLUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; EYE TOXICITY; FLUORESCENCE ANGIOGRAPHY; MEDICAL PHOTOGRAPHY; NICK END LABELING; NONHUMAN; OPHTHALMOSCOPY; PRIORITY JOURNAL; RAT; RETINA TOXICITY; TOXICITY TESTING;

ANIMALS; APOPTOSIS; CELL COUNT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBRINOLYTIC AGENTS; FLUORESCEIN ANGIOGRAPHY; IN SITU NICK-END LABELING; INJECTIONS; RATS; RETINA; RETINAL DISEASES; RETINAL VEIN OCCLUSION; ROSE BENGAL; TISSUE PLASMINOGEN ACTIVATOR; VITREOUS BODY;

EID: 41349095678     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-007-0670-x     Document Type: Article

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