Involvement of MDR1 function in proliferation of tumour cells

Journal of Biochemistry

Volumn 143, Issue 4, 2008, Pages 517-524

  Katoh, Shin Ya ^a   Ueno, Masaya ^a   Takakura, Nobuyuki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Drug resistance; Mdr1; Proliferation; RNAi; Tumour

Indexed keywords

MULTIDRUG RESISTANCE PROTEIN 1;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; GENE REPRESSION; GENE SEQUENCE; GENE SILENCING; IN VITRO STUDY; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL;

ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA PRIMERS; FEMALE; MICE; MICE, INBRED BALB C; P-GLYCOPROTEIN; RECTAL NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS;

EID: 41349093334     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvm242     Document Type: Article

References (30)

1. Gottesman, M.M., Fojo, T., and Bates, S.E. (2002) Multidrug resistance in cancer: role of ATP-dependent transporters. Nat. Rev. Cancer 2, 48-58
2. Juliano, R.L. and Ling, V. (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta 455, 152-162
3. Leonard, G.D., Polgar, O., and Bates, S.E. (2002) ABC transporters and inhibitors: new targets, new agents. Curr. Opin. Investig. Drugs 3, 1652-1659
4. Borowski, E., Bontemps-Gracz, M.M., and Piwkowska, A. (2005) Strategies for overcoming ABC-transporters-mediated multidrug resistance (MDR) of tumor cells. Acta Biochim. Pol. 52, 609-627
5. Ambudkar, S.V., Kimchi-Sarfaty, C., Sauna, Z.E., and Gottesman, M.M. (2003) P-glycoprotein: from genomics to mechanism. Oncogene 22, 7468-7485
6. Cordon-Cardo, C., O'Brien, J.P., Boccia, J., Casals, D., Bertino, J.R., and Melamed, M.R. (1990) Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J. Histochem. Cytochem. 38, 1277-1287
7. Cordon-Cardo, C., O'Brien, J.P., Casals, D., Rittman-Grauer, L., Biedler, J.L., Melamed, M.R., and Bertino, J.R. (1989) Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc. Natl Acad. Sci. USA 86, 695-698
8. Fojo, A.T., Ueda, K., Slamon, D.J., Poplack, D.G., Gottesman, M.M., and Pastan, I. (1987) Expression of a multidrug-resistance gene in human tumors and tissues. Proc. Natl Acad. Sci. USA 84, 265-269
9. Gerlach, J.H., Endicott, J.A., Juranka, P.F., Henderson, G., Sarangi, F., Deuchars, K.L., and Ling, V. (1986) Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance. Nature 324, 485-489
10. Chen, C.J., Chin, J.E., Ueda, K., Clark, D.P., Pastan, I., Gottesman, M.M., and Roninson, I.B. (1986) Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 47, 381-389
11. Gros, P., Croop, J., and Housman, D. (1986) Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell 47, 371-380
12. Hsu, I., Lothstein, L., and Horwitz, S.B. (1989) Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes. J. Biol. Chem. 264, 12053-12062
13. Devault, A. and Gros, P. (1990) Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities. Mol. Cell. Biol. 10, 1652-1663
14. Schinkel, A.H., Smit, J.J., van Tellingen, O., Beijnen, J.H., Wagenaar, E., van Deemter, L., Mol, C.A., van der Valk, M.A., Robanus-Maandag, E.C., te Riele, H.P., Berns, A.J.M., and Borst, P. (1994) Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77, 491-502
15. Schinkel, A.H., Mayer, U., Wagenaar, E., Mol, C.A., van Deemter, L., Smit, J.J., van der Valk, M.A., Voordouw, A.C., Spits, H., van Tellingen, O., Zijlmans, J.M., Fibbe, Q.E., and Borst, P. (1997) Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc. Natl Acad. Sci. USA 94, 4028-4033
16. Jonker, J.W., Buitelaar, M., Wagenaar, E., Van Der Valk, M.A., Scheffer, G.L., Scheper, R.J., Plosch, T., Kuipers, F., Elferink, R.P., Rosing, H., Beijnen, J.H., and Schinkel, A.H. (2002) The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc. Natl Acad. Sci. USA 99, 15649-15654
17. Yamada, T., Mori, Y., Hayashi, R., Takada, M., Ino, Y., Naishiro, Y., Kondo, T., and Hirohashi, S. (2003) Suppression of intestinal polyposis in Mdr1-deficient ApcMin/+ mice. Cancer Res. 63, 895-901
18. Todaro, G.J. and Green, H. (1963) Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J. Cell Biol. 17, 299-313
19. Okamoto, R., Ueno, M., Yamada, Y., Takahashi, N., Sano, H., Suda, T., and Takakura, N. (2005) Hematopoietic cells regulate the angiogenic switch during tumorigenesis. Blood 105, 2757-2763
20. Takakura, N., Watanabe, T., Suenobu, S., Yamada, Y., Noda, T., Ito, Y., Satake, M., and Suda, T. (2000) A role for hematopoietic stem cells in promoting angiogenesis. Cell 102, 199-209
21. Chin, K.V., Ueda, K., Pastan, I., and Gottesman, M.M. (1992) Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. Science 255, 459-462
22. Zastawny, R.L., Salvino, R., Chen, J., Benchimol, S., and Ling, V. (1993) The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53. Oncogene 8, 1529-1535
23. Thottassery, J.V., Zambetti, G.P., Arimori, K., Schuetz, E.G., and Schuetz, J.D. (1997) p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents. Proc. Natl Acad. Sci. USA 94, 11037-11042
24. Yang, J.M., Sullivan, G.F., and Hait, W.N. (1997) Regulation of the function of P-glycoprotein by epidermal growth factor through phospholipase C. Biochem. Pharmacol. 53, 1597-1604
25. Guo, Y.S., Jin, G.F., Houston, C.W., Thompson, J.C., and Townsend, C.M. Jr. (1998) Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells. J. Cell. Physiol. 175, 141-148
26. Israeli, D., Benchaouir, R., Ziaei, S., Rameau, P., Gruszczynski, C., Peltekian, E., Danos, O., and Garcir, L. (2004) FGF6 mediated expansion of a resident subset of cells with SP phenotype in the C2C12 myogenic line. J. Cell Physiol. 201, 409-419
27. Osborn, M.T. and Chambers, T.C. (1996) Role of the stress-activated/ c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J. Biol. Chem. 271, 30950-30955
28. Nooter, K., Westerman, A.M., Flens, M.J., Zaman, G.J., Scheper, R.J., van Wingerden, K.E., Burger, H., Oostrum, R., Boersma, T., Sonneveld, P., Gratama, J.W., Kok, T., Eggermont, A.M.M., Bostman, F.T., and Stoter, G. (1995) Expression of the multidrug resistance-associated protein (MRP) gene in human cancers. Clin. Cancer Res. 1, 1301-1310
29. Duan, Z., Brakora, K.A., and Seiden, M.V. (2004) Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells. Mol. Cancer Ther. 3, 833-838
30. Pichler, A., Zelcer, N., Prior, J.L., Kuil, A.J., and Piwnica-Worms, D. (2005) In vivo RNA interference-mediated ablation of MDR1P-glycoprotein. Clin. Cancer Res. 11, 4487-4494