Spontaneous abortions among nickel-exposed female refinery workers

International Journal of Environmental Health Research

Volumn 18, Issue 2, 2008, Pages 99-115

  Vaktskjold, Arild ^a,b   Talykova, Ljudmila V ^c   Chashchin, Valerij P ^c   Odland, Jon Ø ^a   Nieboer, Evert ^a,d  

^a UNIVERSITY OF TROMSØ   (Norway)

^b NORDIC SCHOOL OF PUBLIC HEALTH   (Sweden)

^c NORTH WEST PUBLIC HEALTH RESEARCH CENTER   (Russian Federation)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

Miscarriage; Nickel; Occupational exposure; Russia; Spontaneous abortion

Indexed keywords

COPPER; NICKEL;

ABORTION; AEROSOL; CONCENTRATION (COMPOSITION); DATA SET; FEMALE; HEALTH RISK; NICKEL; OCCUPATIONAL EXPOSURE; PREGNANCY; REFINING INDUSTRY; URINE;

ADULT; AEROSOL; ARTICLE; CONCENTRATION RESPONSE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DATA ANALYSIS; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; INDUSTRIAL WORKER; MAJOR CLINICAL STUDY; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PREGNANCY; PREGNANCY OUTCOME; RISK ASSESSMENT; RUSSIAN FEDERATION; SELF REPORT; SPONTANEOUS ABORTION; STATISTICAL ANALYSIS; URINALYSIS; WORK ENVIRONMENT; WORKPLACE;

ABORTION, SPONTANEOUS; ADULT; AEROSOLS; AIR POLLUTION, INDOOR; CASE-CONTROL STUDIES; FEMALE; HUMANS; INHALATION EXPOSURE; MATERNAL EXPOSURE; METALLURGY; NICKEL; OCCUPATIONAL EXPOSURE; ODDS RATIO; PREGNANCY; PREGNANCY OUTCOME; RISK; RUSSIA; SOLUBILITY;

EURASIA; RUSSIAN FEDERATION;

EID: 41349086889     PISSN: 09603123     EISSN: 13691619     Source Type: Journal    
DOI: 10.1080/09603120701498295     Document Type: Article

References (45)

1. Agency for Toxic Substances and Disease Registry (ATSDR). 2001. Draft toxicological profile for cobalt. Atlanta (Georgia): The Registry, US Department of Health and Human Services.
2. Agnesi R, Valentini F, Mastrangelo G. 1997. Risk of spontaneous abortion and maternal exposure to organic solvents in the shoe industry. Int Arch Occup Environ Health. 69:311-316.
3. Bobak M, Gilmore A, McKee M, Rose R, Marmot M. 2006. Changes in smoking prevalence in Russia, 1996 - 2004. Tob Control. 15(2):131-135.
4. Chashschin VP, Artunina GP, Norseth T. 1994. Congenital-defects, abortion and other healtheffects in nickel refinery workers. Sci Total Environ. 148(2-3):287-291.
5. Chen CY, Lin TH. 1998. Nickel toxicity to human term placenta: in vitro study on lipid peroxidation. J Toxicol Environ Health. 54(1):37-47.
6. [CCTR] Committee for Compounds Toxic to Reproduction. 2003. Nickel and its compounds; Evaluation of the effects on reproduction, recommendation for classification. The Hague: Health Council of the Netherlands. publication no. 2, ISBN: 90-5549-466-6. Available from: http://www.gr.nl/pdf.php?ID=638&p=1
7. De la Rochebrochard E, Thonneau P. 2002. Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European study. Hum Reprod. 17(6):1649-1656.
8. Eiben B, Bartels I, Bähr-Porsch S, Borgmann S, Gatz G, Gellert G, Goebel R, Hammans W, Hentemann M, Osmers R, et al. 1990. Cytogenic analysis of 750 spontanous abortions with the direct-preparation method of chronic villi and its implication for studying genetic causes of pregnancy wastage. Am J Hum Genet. 47:656-663.
9. European Commission. 1993. Commission Directive 93/21/EEC of 27 April 1993 adapting to technical progress for the 18th time Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances.
10. Fantel AG, Shepard TH. 1987. Cited in Stirrat GM. 1990. Recurrent miscarriage I: Definition and epidemiology [Review]. Lancet. 336:673-675.
11. Gerhard I, Waibel S, Daniel V, Runnebaum. 1998. Impact of heavy metals on hormonal and immunological factors in women with repeated miscarriages. Hum Reprod Update. 4(3):301-309.
12. Hemminki E, Forssas E. 1999. Epidemiology of miscarriage and its relation to other reproductive events in Finland. Am J Obstet Gynecol. 181(2):396-401.
13. Knudsen UB, Hansen V, Juul S, Secher NJ. 1991. Prognosis of a new pregnancy following previous spontaneous abortions. Eur J Obstet Gynecol Reprod Biol. 39:31-36.
14. McMartin KI, Chu M, Kopecky E, Einarson TR, Koren G. 1998. Pregnancy outcome following maternal organic solvent exposure: A meta analysis if epidemiologic studies. Am J Ind Med. 34:288-292.
15. Midtgard U, Binderup ML. 1994. The Nordic Expert Group for Criteria Documentation of Health Risks for Chemicals, Vol. 114, Cobalt and cobalt compounds. Solna (Sweden): National Institute of Occupational Health. Arbete och Halsa Vetenskaplig Skriftserie 1994:139.
16. Miller JR, Poland BJ. 1970. The value of human abortuses in the surveillance of developmental anomalies. I. General overview. Can Med Assoc J. 103(5):501-502.
17. Modvig J, Shmidt L, Damsgaard T. 1990. Measurement of total risk of spontaneous abortion: The virtue of conditional risk estimation. Am J Epidemiol. 132(6):1021-1038.
18. Moore KL, Persaud TV. 2003. Before we are born. Essentials of embryology and birth defects. . 6th ed. Philadelphia: Saunders.
19. Morgan J. 1996. Principles of epidemiology. 1st ed. Bryn Mawr: MDM Consulting.
20. Nieboer E, Fletcher GG, Thomassen Y. 1999. Relevance of reactivity determinants to exposure assessment and biological monitoring of the elements. J Environ Monit. 1(1):1-14.
21. Nieboer E, Sanford WE, Stace BC. 1992. Absorption, distribution and excretion of nickel. In: Nieboer E, Nriagu JO, editors. Nickel and human health. Current perspectives. Advances in environmental science and technology. New York: John Wiley & Sons. p. 49-68.
22. Nieboer E, Thomassen Y, Romanova N, Nikonov A, Odland JO, Chashchin V. 2007. Multicomponent assessment of worker exposures in a copper refinery. Part 2. Biological exposure indices for copper, nickel and cobalt. J Environ Monit. 9(7):695-700.
23. Nurminen T. 1998. Shift work and reproductive health. Scand J Work Environ Health. 24(Suppl 3):28-34.
24. Nybo Andersen AM, Wohlfahrt J, Christens P, Olsen J, Melbye M. 2000. Maternal age and fetal loss: Population-based register linkage study. BMJ. 320:1708-1712.
25. Obel EB. 1980. Risk of spontaneous abortion following legally induced abortion. Acta Obstet Gynecol Scand. 59(2):131-135.
26. Odland JO, Nieboer E, Romanova N, Thomassen Y, Norseth T, Lund E. 1999a. Urinary nickel concentrations and selected pregnancy outcomes in delivering women and their newborns among arctic populations of Norway and Russia. J Environ Monit. 1(2):153-161.
27. Odland JO, Tchachtchine VP, Bykov V, Fiskebeck PE, Lund E, Thomassen Y, Nieboer E. 1999b. Critical evaluation of medical, statistical, and occupational data sources in the Kola Peninsula of Russia pertinent to reproductive health studies. Int Arch Occup Environ Health. 72(3):151-160.
28. Osborn JF, Cattaruzza MS, Spinelli A. 2000. Risk of spontaneous abortion in Italy, 1978 - 1995, and the effect of maternal age, gravidity, marital status, and education. Am J Epidemiol. 151(1):98-105.
29. Regan L, Rai R. 2000. Epidemiology and the medical causes of miscarriage [Summary]. Baill Clin Obstet Gynaecol. 14(5):839-854.
30. Reimann C, Äyräs M, Chekushin VA. 1998. Environmental geochemical atlas of the central Barents region. Trondheim (Norway): Norges geologiske undersøkelse.
31. Selevan SG, Lemasters GK. 1987. The dose-response fallacy in human reproductive studies of toxic exposures. J Occup Med. 29(5):451-454.
32. Stirrat GM. 1990. Recurrent miscarriage I: Definition and epidemiology [Review]. Lancet. 336:673-675.
33. Sun Y, Che Y, Gao E, Olsen J, Zhou W. 2003. Induced abortion and risk of subsequent miscarriage. Perinat Epidemiol. 32:449-454.
34. Sunderman FW, Jr. 1977. A review of the metabolism and toxicology of nickel. Ann Clin Lab Sci. 7(5):377-398.
35. Sunderman FW, Jr. 1993. Biological monitoring of nickel in humans. Scand JWork Environ Health. 19(Suppl. 1):34-38.
36. Talykova LV, Vaktskjold A, Serebrjakova NG, Khokhlov TG, Strelkovskaja NJ, Chashschin VP, Nikanov AN, Odland JØ, Bykov V, Nieboer E. 2007. Pregnancy health and outcome in two cities in the Kola Peninsula, north-western Russia. Int J Circumpolar Health. 66(2):168-181.
37. Taskinen H. 1990. Effects of parental occupational exposures on spontaneous abortion and congenital malformation [Review]. Scand J Work Environ Health. 16:297-314.
38. Thomassen Y, Nieboer E, Ellingsen D, Hetland S, Norseth T, Odland JO, Romanova N, Chernova S, Tchachtchine VP. 1999. Characterisation of workers' exposure in a Russian nickel refinery. J Environ Monit. 1(1):15-22.
39. Thomassen Y, Nieboer E, Romanova N, Nikanov A, Hetland S, VanSpronsen EP, Odland JO, Chashchin V. 2004. Multi-component assessment of worker exposures in a copper refinery. Part 1. Environmental monitoring. J Environ Monit. 6(12):985-991.
40. US Department of Health and Human Services. 2004. The health consequences of smoking: A Report of the Surgeon General. Atlanta, Georgia: US: Department of Health and Human Services, Centers for Disease Control, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health.
41. Vaktskjold A, Talykova L, Chashchin V, Nieboer E, Odland JØ. 2004a. The Kola Birth Registry and perinatal mortality in Montsjegorsk, Russia. Acta Obstet Gynecol Scand. 83(1):58-69.
42. Vaktskjold A, Paulsen EA, Talykova L, Nieboer E, Odland JO. 2004b. The prevalence of selected pregnancy outcome risk factors in the lifestyle and medical history of the delivering population in north-western Russia. Int J Circumpolar Health. 63(1):39-60.
43. Vaktskjold A, Talykova LV, Chashchin VP, Nieboer E, Thomassen Y, Odland JØ. 2006. Genital malformations in newborns of female nickel-refinery workers. Scand J Work Environ Health. 32(1):41-50.
44. Wilcox A, Weinberg C, O'Connor J, Baird D, Schlatterer J, Canfield R, Armstrong E, Nisula B. 1988. Incidence of early loss of pregnancy. N Engl J Med. 319:189-194.
45. Windham GC, Shusterman D, Swan SH, Fenster L, Eskenazi B. 1991. Exposure to organic solvents and adverse pregnancy outcome. Am J Ind Med. 20(2):241-259.