Synthesis and anticonvulsant activity of some novel 3-aryl amino/amino-4-aryl-5-imino-Δ2-1,2,4-thiadiazoline

European Journal of Medicinal Chemistry

Volumn 43, Issue 4, 2008, Pages 749-754

  Gupta, Arun ^a   Mishra, Pradeep ^a   Kashaw, Sushil K ^a   Jatav, Varsha ^a   Stables, J P ^b  

^a DR H S GOUR UNIVERSITY   (India)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Anticonvulsant; Neurotoxicity; Thiadiazoline

Indexed keywords

5 IMINO DELTA2 1,2,4 THIADIAZOLINE DERIVATIVE; ANTICONVULSIVE AGENT; PENTETRAZOLE; PHENOBARBITAL; THIADIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG SCREENING; DRUG SYNTHESIS; HYPNOSIS; MALE; MAXIMAL ELECTROSHOCK INDUCED SEIZURE; MOUSE; NEUROTOXICITY; NONHUMAN; SEIZURE;

ANIMALS; ANTICONVULSANTS; ELECTROSHOCK; IMMOBILITY RESPONSE, TONIC; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MOLECULAR STRUCTURE; PENTYLENETETRAZOLE; RATS; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINES;

EID: 41249089500     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.05.008     Document Type: Article

References (9)

1. Loscher W. Eur. J. Pharmacol. 342 (1998) 1-13
2. Scheuer M.L., and Pedley T.A. N. Engl. J. Med. 323 (1990) 1468-1474
3. Browne T.R., and Holmes G.L. N. Engl. J. Med. 344 (2001) 1145-1151
4. Brodie M.J. Lancet 336 (1990) 350-354
5. Eadia M.J. Drugs 27 (1984) 328-363
6. Aggarwal N., and Mishra P. J. Pharm. Pharm. Sci. 7 (2004) 260-264
7. Aggarwal N., and Mishra P. J. Zhejiang Univ. Sci. 6B (2005) 617-621
8. Krall R.L., Penry J.K., White B.G., Kupferberg H.J., and Swinyard E.A. Epilepsia 19 (1978) 409-428
9. Porter R.J., Hessie B.J., Cereghino J.J., Gladding G.D., Kupferberg H.J., Scoville B., and White B.G. Fed. Proc. 44 (1985) 2645-2649