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Volumn 45, Issue 2, 2008, Pages 75-84

Monoclonal Antibodies for the Treatment of Hematologic Malignancies: Schedule and Maintenance Therapy

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; CORTICOSTEROID; CYCLOPHOSPHAMIDE; GEMTUZUMAB OZOGAMICIN; MONOCLONAL ANTIBODY; PARACETAMOL; PREDNISOLONE; RITUXIMAB; VINCRISTINE;

EID: 41149180913     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2008.02.006     Document Type: Article
Times cited : (9)

References (74)
  • 1
    • 0028127304 scopus 로고
    • Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney D.G., Liles T.M., Czerwinski D.K., Waldichuk C., Rosenberg J., Grillo-Lopez A., et al. Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood 84 (1994) 2457-2466
    • (1994) Blood , vol.84 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3    Waldichuk, C.4    Rosenberg, J.5    Grillo-Lopez, A.6
  • 2
    • 0036721023 scopus 로고    scopus 로고
    • Glucocorticoids and rituximab in vitro; synergistic direct antiproliferative and apoptotic effects
    • Rose A.L., Smith B.E., and Maloney D.G. Glucocorticoids and rituximab in vitro; synergistic direct antiproliferative and apoptotic effects. Blood 100 (2002) 1765-1773
    • (2002) Blood , vol.100 , pp. 1765-1773
    • Rose, A.L.1    Smith, B.E.2    Maloney, D.G.3
  • 3
    • 7844225540 scopus 로고    scopus 로고
    • Association of serum Rituximab (IDEC-C2B8) concentration and anti-tumor response in the treatment of recurrent low-grade or follicular non-Hodgkin's lymphoma
    • Berinstein N.L., Grillo-López A.J., White C.A., Bence-Bruckler I., Maloney D., Czuczman M., et al. Association of serum Rituximab (IDEC-C2B8) concentration and anti-tumor response in the treatment of recurrent low-grade or follicular non-Hodgkin's lymphoma. Ann Oncol 9 (1998) 995-1001
    • (1998) Ann Oncol , vol.9 , pp. 995-1001
    • Berinstein, N.L.1    Grillo-López, A.J.2    White, C.A.3    Bence-Bruckler, I.4    Maloney, D.5    Czuczman, M.6
  • 4
    • 17144455839 scopus 로고    scopus 로고
    • IDEC-C2B8: Results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma
    • Maloney D., Grillo-Lopez A., Bodkin D., White C., Liles T., Royston I., et al. IDEC-C2B8: Results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma. J Clin Oncol 15 (1997) 3266-3274
    • (1997) J Clin Oncol , vol.15 , pp. 3266-3274
    • Maloney, D.1    Grillo-Lopez, A.2    Bodkin, D.3    White, C.4    Liles, T.5    Royston, I.6
  • 5
    • 0345337254 scopus 로고    scopus 로고
    • Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
    • McLaughlin P., Grillo-López A.J., Link B.K., Levy R., Czuczman M.S., Williams M.E., et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program. J Clin Oncol 16 (1998) 2825-2833
    • (1998) J Clin Oncol , vol.16 , pp. 2825-2833
    • McLaughlin, P.1    Grillo-López, A.J.2    Link, B.K.3    Levy, R.4    Czuczman, M.S.5    Williams, M.E.6
  • 6
    • 0032530342 scopus 로고    scopus 로고
    • Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: A multicenter phase II study
    • Coiffier B., Haioun C., Ketterer N., Engert A., Tilly D., Johnson P., et al. Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: A multicenter phase II study. Blood 92 (1998) 1927-1932
    • (1998) Blood , vol.92 , pp. 1927-1932
    • Coiffier, B.1    Haioun, C.2    Ketterer, N.3    Engert, A.4    Tilly, D.5    Johnson, P.6
  • 8
    • 0038446696 scopus 로고    scopus 로고
    • Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance
    • Manshouri T., Do K., Wang X., Giles F.J., O'Brien S.M., Saffer H., et al. Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance. Blood 101 (2003) 2507-2513
    • (2003) Blood , vol.101 , pp. 2507-2513
    • Manshouri, T.1    Do, K.2    Wang, X.3    Giles, F.J.4    O'Brien, S.M.5    Saffer, H.6
  • 9
    • 0032791210 scopus 로고    scopus 로고
    • Extended rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma
    • Piro L.D., White C.A., Grillo-López A.J., Janakiraman N., Saven A., Beck T.M., et al. Extended rituximab (anti-CD20 monoclonal antibody) therapy for relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma. Ann Oncol 10 (1999) 655-661
    • (1999) Ann Oncol , vol.10 , pp. 655-661
    • Piro, L.D.1    White, C.A.2    Grillo-López, A.J.3    Janakiraman, N.4    Saven, A.5    Beck, T.M.6
  • 10
    • 1542405230 scopus 로고    scopus 로고
    • Semi-extended, six weekly rituximab infusions in pre-treated advanced low-grade B cell non-Hodgkin's lymphoma: A phase II study
    • Bremer K. Semi-extended, six weekly rituximab infusions in pre-treated advanced low-grade B cell non-Hodgkin's lymphoma: A phase II study. Anticancer Drugs 14 (2003) 809-815
    • (2003) Anticancer Drugs , vol.14 , pp. 809-815
    • Bremer, K.1
  • 11
    • 14544274608 scopus 로고    scopus 로고
    • Phase II trial of individualized rituximab dosing for patients with CD20-positive lymphoproliferative disorders
    • Gordan L.N., Grow W.B., Pusateri A., Douglas V., Mendenhall N.P., and Lynch J.W. Phase II trial of individualized rituximab dosing for patients with CD20-positive lymphoproliferative disorders. J Clin Oncol 23 (2005) 1096-1102
    • (2005) J Clin Oncol , vol.23 , pp. 1096-1102
    • Gordan, L.N.1    Grow, W.B.2    Pusateri, A.3    Douglas, V.4    Mendenhall, N.P.5    Lynch, J.W.6
  • 12
    • 0344766075 scopus 로고    scopus 로고
    • Treatment of patients with low-grade B-Cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy
    • Czuczman M.S., Grillo-López A.J., White C.A., Saleh M., Gordon A., LoBuglio A.F., et al. Treatment of patients with low-grade B-Cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy. J Clin Oncol 17 (1999) 268-276
    • (1999) J Clin Oncol , vol.17 , pp. 268-276
    • Czuczman, M.S.1    Grillo-López, A.J.2    White, C.A.3    Saleh, M.4    Gordon, A.5    LoBuglio, A.F.6
  • 13
    • 0035871445 scopus 로고    scopus 로고
    • Rituximab using a Thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
    • Byrd J.C., Murphy T., Howard R.S., Lucas M.S., Goodrich A., Pearson M., et al. Rituximab using a Thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J Clin Oncol 19 (2001) 2153-2164
    • (2001) J Clin Oncol , vol.19 , pp. 2153-2164
    • Byrd, J.C.1    Murphy, T.2    Howard, R.S.3    Lucas, M.S.4    Goodrich, A.5    Pearson, M.6
  • 14
    • 33947667466 scopus 로고    scopus 로고
    • Rapid infusion rituximab in combination with corticosteroid-containing chemotherapy or as maintenance therapy is well tolerated and can be safely be delivered in the community setting
    • Sehn L.H., Donaldson J., Filewich A., Fitzgerald C., Gill K.K., Runzer N., et al. Rapid infusion rituximab in combination with corticosteroid-containing chemotherapy or as maintenance therapy is well tolerated and can be safely be delivered in the community setting. Blood 109 (2007) 4171-4173
    • (2007) Blood , vol.109 , pp. 4171-4173
    • Sehn, L.H.1    Donaldson, J.2    Filewich, A.3    Fitzgerald, C.4    Gill, K.K.5    Runzer, N.6
  • 15
    • 33748352027 scopus 로고    scopus 로고
    • Rapid infusion of rituximab with or without steroid-containing chemotherapy: 1-yr experience in a single institution
    • Salar A., Casao D., Cervera M., Pedro C., Calafell M., Abella E., et al. Rapid infusion of rituximab with or without steroid-containing chemotherapy: 1-yr experience in a single institution. Eur J Haematol 77 (2006) 338-340
    • (2006) Eur J Haematol , vol.77 , pp. 338-340
    • Salar, A.1    Casao, D.2    Cervera, M.3    Pedro, C.4    Calafell, M.5    Abella, E.6
  • 16
    • 41149178774 scopus 로고    scopus 로고
    • Siano M, Lerch E, Zucca E, Mora O, Sessa C, Ghielmini M: A phase I-II study to determine the maximum tolerated infusion-rate of rituximab, with a special emphasis on monitoring the effect of rituximab on cardiac function. ASH abstr 3411.
    • Siano M, Lerch E, Zucca E, Mora O, Sessa C, Ghielmini M: A phase I-II study to determine the maximum tolerated infusion-rate of rituximab, with a special emphasis on monitoring the effect of rituximab on cardiac function. ASH abstr 3411.
  • 18
    • 0038811776 scopus 로고    scopus 로고
    • Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: A phase II trial of the Minnie Pearl Cancer Research Network
    • Hainsworth J.D., Litschy S., Lamb M.R., Rodriguez G.I., Scroggin Jr. C., and Greco F.A. Single-agent rituximab as first-line and maintenance treatment for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma: A phase II trial of the Minnie Pearl Cancer Research Network. J Clin Oncol 21 (2003) 1746-1751
    • (2003) J Clin Oncol , vol.21 , pp. 1746-1751
    • Hainsworth, J.D.1    Litschy, S.2    Lamb, M.R.3    Rodriguez, G.I.4    Scroggin Jr., C.5    Greco, F.A.6
  • 19
    • 14544276412 scopus 로고    scopus 로고
    • Maximizing therapeutic benefit of rituximab: Maintenance therapy versus re-treatment at progression in patients with indolent non-Hodgkin's lymphoma: A randomized phase II trial of the Minnie Pearl Cancer Research Network
    • Hainsworth J.D., Litchy S., Shaffer D.W., Lackey V.L., Grimaldi M., and Greco F.A. Maximizing therapeutic benefit of rituximab: Maintenance therapy versus re-treatment at progression in patients with indolent non-Hodgkin's lymphoma: A randomized phase II trial of the Minnie Pearl Cancer Research Network. J Clin Oncol 23 (2005) 1088-1095
    • (2005) J Clin Oncol , vol.23 , pp. 1088-1095
    • Hainsworth, J.D.1    Litchy, S.2    Shaffer, D.W.3    Lackey, V.L.4    Grimaldi, M.5    Greco, F.A.6
  • 20
    • 2942567554 scopus 로고    scopus 로고
    • Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly × 4 schedule
    • Ghielmini M., Hsu-Schmitz S.F., Cogliatti S.B., Pichert G., Hummerjohann J., Walzer U., et al. Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly × 4 schedule. Blood 103 (2004) 4416-4423
    • (2004) Blood , vol.103 , pp. 4416-4423
    • Ghielmini, M.1    Hsu-Schmitz, S.F.2    Cogliatti, S.B.3    Pichert, G.4    Hummerjohann, J.5    Walzer, U.6
  • 21
    • 20044381673 scopus 로고    scopus 로고
    • Effect of single-agent Rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: A study of the Swiss Group for Clinical Cancer Research (SAKK)
    • Ghielmini M., Hsu-Schmitz S., Cogliatti S., Bertoni F., Waltzer U., Fey M.F., et al. Effect of single-agent Rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: A study of the Swiss Group for Clinical Cancer Research (SAKK). J Clin Oncol 4 (2005) 705-711
    • (2005) J Clin Oncol , vol.4 , pp. 705-711
    • Ghielmini, M.1    Hsu-Schmitz, S.2    Cogliatti, S.3    Bertoni, F.4    Waltzer, U.5    Fey, M.F.6
  • 22
    • 5744223285 scopus 로고    scopus 로고
    • Results of E1496: A phase III trial of CVP with or without maintenance rituximab in advanced indolent lymphoma (NHL)
    • (abstr)
    • Hochster H.S., Weller E., Ryan T., Habermann T.M., Gascoyne R., Frankel S.R., et al. Results of E1496: A phase III trial of CVP with or without maintenance rituximab in advanced indolent lymphoma (NHL). J Clin Oncol 22 suppl (2004) 558s (abstr)
    • (2004) J Clin Oncol , vol.22 , Issue.SUPPL
    • Hochster, H.S.1    Weller, E.2    Ryan, T.3    Habermann, T.M.4    Gascoyne, R.5    Frankel, S.R.6
  • 23
    • 33646858706 scopus 로고    scopus 로고
    • Maintenance rituximab after CVP results in superior clinical outcome in advanced follicular lymphoma (FL): Results of the E1496 phase III trial from the Eastern Cooperative Oncology Group and the Cancer and Leukemia Group B
    • (abstr)
    • Hochster H.S., Weller E., Gascoyne R.D., Ryan T.S., Habermann T.M., Gordon L.I., et al. Maintenance rituximab after CVP results in superior clinical outcome in advanced follicular lymphoma (FL): Results of the E1496 phase III trial from the Eastern Cooperative Oncology Group and the Cancer and Leukemia Group B. Blood 106 (2005) 106a (abstr)
    • (2005) Blood , vol.106
    • Hochster, H.S.1    Weller, E.2    Gascoyne, R.D.3    Ryan, T.S.4    Habermann, T.M.5    Gordon, L.I.6
  • 24
    • 33747046630 scopus 로고    scopus 로고
    • The role of rituximab maintenance treatment in relapsed follicular NHL: An interim analysis of the EORTC randomized intergroup trial
    • (abstr)
    • Hagenbeek A., Van Glabbeke M., Teodorovic I., et al. The role of rituximab maintenance treatment in relapsed follicular NHL: An interim analysis of the EORTC randomized intergroup trial. Ann Oncol 16 (2005) v52 (abstr)
    • (2005) Ann Oncol , vol.16
    • Hagenbeek, A.1    Van Glabbeke, M.2    Teodorovic, I.3
  • 25
    • 13644249821 scopus 로고    scopus 로고
    • Rituximab-CHOP versus CHOP with or withou maintenance rituximab in patients 60 years of age or older with diffuse large B-cell lymphoma (DLBCL): An update
    • (abstr 127)
    • Habermann T.M., Weller E., Morrison V.A., et al. Rituximab-CHOP versus CHOP with or withou maintenance rituximab in patients 60 years of age or older with diffuse large B-cell lymphoma (DLBCL): An update. Blood 104 (2004) 40a (abstr 127)
    • (2004) Blood , vol.104
    • Habermann, T.M.1    Weller, E.2    Morrison, V.A.3
  • 26
    • 8744274334 scopus 로고    scopus 로고
    • The addition of rituximab to a combination of fludarabine, cyclophosphamide and mitoxantrone (FCM) significantly prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphoma-Results of a prospective randomized study of the German Low Grade Lymphoma Study Group
    • Forstpointner R., Dreyling M., Repp R., Hermann S., Hanel A., Metzner B., et al. The addition of rituximab to a combination of fludarabine, cyclophosphamide and mitoxantrone (FCM) significantly prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphoma-Results of a prospective randomized study of the German Low Grade Lymphoma Study Group. Blood 104 (2004) 3064-3071
    • (2004) Blood , vol.104 , pp. 3064-3071
    • Forstpointner, R.1    Dreyling, M.2    Repp, R.3    Hermann, S.4    Hanel, A.5    Metzner, B.6
  • 27
    • 33749545033 scopus 로고    scopus 로고
    • Rituximab maintenance improves clinical outcome of relapsed/resistant follicular non-Hodgkin's lymphoma, both in patients with and without rituximab during induction: Results of a prospective randomized phase III intergroup trial
    • van Oers M.H.J., Klasa R., Marcus R.E., Wolf M., Kimby E., Gascoyne R.D., et al. Rituximab maintenance improves clinical outcome of relapsed/resistant follicular non-Hodgkin's lymphoma, both in patients with and without rituximab during induction: Results of a prospective randomized phase III intergroup trial. Blood 108 (2006) 3295-3301
    • (2006) Blood , vol.108 , pp. 3295-3301
    • van Oers, M.H.J.1    Klasa, R.2    Marcus, R.E.3    Wolf, M.4    Kimby, E.5    Gascoyne, R.D.6
  • 28
    • 9444247655 scopus 로고    scopus 로고
    • Rituximab consolidation after high-dose chemotherapy and autologous blood stem cell transplantation in follicular and mantle cell lymphoma: A prospective multicenter phase II study
    • Brugger W., Hirsch J., Grüneback F., Repp R., Brossart P., Vogel W., et al. Rituximab consolidation after high-dose chemotherapy and autologous blood stem cell transplantation in follicular and mantle cell lymphoma: A prospective multicenter phase II study. Ann Oncol 15 (2004) 1691-1698
    • (2004) Ann Oncol , vol.15 , pp. 1691-1698
    • Brugger, W.1    Hirsch, J.2    Grüneback, F.3    Repp, R.4    Brossart, P.5    Vogel, W.6
  • 29
    • 10744227230 scopus 로고    scopus 로고
    • Intensive chemotherapy and autologous stem-cell transplantation plus rituximab is superior to conventional chemotherapy for newly diagnosed advanced stage mantle cell lymphoma: A matched pair analysis
    • Mangel J., Leitch H.A., Connors J.M., Buckstein R., Imrie K., Spaner D., et al. Intensive chemotherapy and autologous stem-cell transplantation plus rituximab is superior to conventional chemotherapy for newly diagnosed advanced stage mantle cell lymphoma: A matched pair analysis. Ann Oncol 15 (2004) 283-290
    • (2004) Ann Oncol , vol.15 , pp. 283-290
    • Mangel, J.1    Leitch, H.A.2    Connors, J.M.3    Buckstein, R.4    Imrie, K.5    Spaner, D.6
  • 30
    • 33748094114 scopus 로고    scopus 로고
    • Rituximab long-term maintenance therapy after autologous stem cell transplantation in patients with B cell non-Hodgkin's lymphoma
    • Neumann F., Harnsen S., Martin S., Kronenwett R., Kondakei M., Aivado M., et al. Rituximab long-term maintenance therapy after autologous stem cell transplantation in patients with B cell non-Hodgkin's lymphoma. Ann Hematol 85 (2006) 530-534
    • (2006) Ann Hematol , vol.85 , pp. 530-534
    • Neumann, F.1    Harnsen, S.2    Martin, S.3    Kronenwett, R.4    Kondakei, M.5    Aivado, M.6
  • 31
    • 0027240401 scopus 로고
    • Effect of Campath-H1 antibody on human hematopoietic progenitors in vitro
    • Gilleece M.H., and Dexter T.M. Effect of Campath-H1 antibody on human hematopoietic progenitors in vitro. Blood 82 (1993) 807-812
    • (1993) Blood , vol.82 , pp. 807-812
    • Gilleece, M.H.1    Dexter, T.M.2
  • 32
    • 0023009274 scopus 로고
    • Ex vivo T cell depletion with the monoclonal antibody Campath-1 plus human complement effectively prevents acute graft versus-host disease in allogeneic bone marrow transplantation
    • Heit W., Bunjes D., Wiesneth M., Schmeiser T., Arnold R., Hale G., et al. Ex vivo T cell depletion with the monoclonal antibody Campath-1 plus human complement effectively prevents acute graft versus-host disease in allogeneic bone marrow transplantation. Br J Haematol 64 (1986) 479-486
    • (1986) Br J Haematol , vol.64 , pp. 479-486
    • Heit, W.1    Bunjes, D.2    Wiesneth, M.3    Schmeiser, T.4    Arnold, R.5    Hale, G.6
  • 33
    • 0024566393 scopus 로고
    • Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype
    • Dyer M.J., Hale G., Hayhoe F.G., and Waldmann H. Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype. Blood 73 (1989) 1431-1439
    • (1989) Blood , vol.73 , pp. 1431-1439
    • Dyer, M.J.1    Hale, G.2    Hayhoe, F.G.3    Waldmann, H.4
  • 34
    • 0031790767 scopus 로고    scopus 로고
    • Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells
    • Rowan W., Tite J., Topley P., and Brett S.J. Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells. Immunology 95 (1998) 427-436
    • (1998) Immunology , vol.95 , pp. 427-436
    • Rowan, W.1    Tite, J.2    Topley, P.3    Brett, S.J.4
  • 35
    • 0027283918 scopus 로고
    • Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen
    • Xia M.Q., Hale G., and Waldmann H. Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen. Mol Immunol 30 (1993) 1089-1096
    • (1993) Mol Immunol , vol.30 , pp. 1089-1096
    • Xia, M.Q.1    Hale, G.2    Waldmann, H.3
  • 36
  • 38
    • 34548028700 scopus 로고    scopus 로고
    • Population pharmacokinetics-pharmacodynamics of alemtuzumab (Campath) in patients with chronic lymphocytic leukemia and its link to treatment response
    • Mould D.R., Baumann A., Kuhlmann J., Keating M.J., Weitman S., Hillmen, et al. Population pharmacokinetics-pharmacodynamics of alemtuzumab (Campath) in patients with chronic lymphocytic leukemia and its link to treatment response. Br J Clin Pharmacol 64 (2007) 278-291
    • (2007) Br J Clin Pharmacol , vol.64 , pp. 278-291
    • Mould, D.R.1    Baumann, A.2    Kuhlmann, J.3    Keating, M.J.4    Weitman, S.5    Hillmen6
  • 39
    • 33744793781 scopus 로고    scopus 로고
    • Alemtuzumab as consolidation after a response to fludarabine is effective in purging residual disease in patients with chronic lymhpocytic leucemia
    • Montillo M., Tedeschi A., Miqueleiz S., Veronese S., Cairoli R., Intropido L., et al. Alemtuzumab as consolidation after a response to fludarabine is effective in purging residual disease in patients with chronic lymhpocytic leucemia. J Clin Oncol 24 (2006) 2337-2342
    • (2006) J Clin Oncol , vol.24 , pp. 2337-2342
    • Montillo, M.1    Tedeschi, A.2    Miqueleiz, S.3    Veronese, S.4    Cairoli, R.5    Intropido, L.6
  • 40
    • 0024204319 scopus 로고
    • Remission induction in non-Hodgkin lymphoma with reshaped human antibody CAMPATH-1H
    • Hale G., Dyer M.J.S., Clark M.R., Philipps J.M., Marcus R., Riechmann L., et al. Remission induction in non-Hodgkin lymphoma with reshaped human antibody CAMPATH-1H. Lancet 2 (1988) 1394-1399
    • (1988) Lancet , vol.2 , pp. 1394-1399
    • Hale, G.1    Dyer, M.J.S.2    Clark, M.R.3    Philipps, J.M.4    Marcus, R.5    Riechmann, L.6
  • 41
    • 0030897222 scopus 로고    scopus 로고
    • Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia
    • Osterborg A., Dyer M.J., Bunjes D., Pangalis G.A., Bastion Y., Catovsky D., et al. Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia. J Clin Oncol 15 (1997) 1567-1574
    • (1997) J Clin Oncol , vol.15 , pp. 1567-1574
    • Osterborg, A.1    Dyer, M.J.2    Bunjes, D.3    Pangalis, G.A.4    Bastion, Y.5    Catovsky, D.6
  • 42
    • 0037106502 scopus 로고    scopus 로고
    • Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine
    • Rai K.R., Freter C.E., Mercier R.J., Cooper M.R., Mitchell B.S., Stadtmauer E.A., et al. Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine. J Clin Oncol 20 (2002) 3891-3897
    • (2002) J Clin Oncol , vol.20 , pp. 3891-3897
    • Rai, K.R.1    Freter, C.E.2    Mercier, R.J.3    Cooper, M.R.4    Mitchell, B.S.5    Stadtmauer, E.A.6
  • 43
    • 0037092951 scopus 로고    scopus 로고
    • Therapeutic role of alemtuzumab (campath-1H) in patients who have failed fludarabine: Results of a large international study
    • Keating M.J., Flinn I., Jain V., Binet J.L., Hillmen P., Byrd J., et al. Therapeutic role of alemtuzumab (campath-1H) in patients who have failed fludarabine: Results of a large international study. Blood 99 (2002) 3554-3561
    • (2002) Blood , vol.99 , pp. 3554-3561
    • Keating, M.J.1    Flinn, I.2    Jain, V.3    Binet, J.L.4    Hillmen, P.5    Byrd, J.6
  • 46
    • 0036139106 scopus 로고    scopus 로고
    • Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed
    • Keating M.J., Cazin B., Coutré S., Birhray R., Kovacsovics T., Langer B., et al. Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed. J Clin Oncol 20 (2001) 205-213
    • (2001) J Clin Oncol , vol.20 , pp. 205-213
    • Keating, M.J.1    Cazin, B.2    Coutré, S.3    Birhray, R.4    Kovacsovics, T.5    Langer, B.6
  • 47
    • 1842579580 scopus 로고    scopus 로고
    • A pilot study of alemtuzumab (anti-CD52 monoclonal antibody) therapy for patients with relapsed or chemotherapy-refractory peripheral T-cell lymphomas
    • Enblad G., Hagberg H., Erlanson M., Lundin J., MacDonald A.P., Repp R., et al. A pilot study of alemtuzumab (anti-CD52 monoclonal antibody) therapy for patients with relapsed or chemotherapy-refractory peripheral T-cell lymphomas. Blood 103 (2004) 2920-2924
    • (2004) Blood , vol.103 , pp. 2920-2924
    • Enblad, G.1    Hagberg, H.2    Erlanson, M.3    Lundin, J.4    MacDonald, A.P.5    Repp, R.6
  • 48
    • 20344379951 scopus 로고    scopus 로고
    • Preliminary observations of a phase II study of reduced-dose alemtuzumab in patients with pretreated T-cell lymphoma
    • Zinzani P.L., Alinari L., Tani M., Fina M., Pileri S., and Baccarani M. Preliminary observations of a phase II study of reduced-dose alemtuzumab in patients with pretreated T-cell lymphoma. Haematologica 90 (2005) 702-703
    • (2005) Haematologica , vol.90 , pp. 702-703
    • Zinzani, P.L.1    Alinari, L.2    Tani, M.3    Fina, M.4    Pileri, S.5    Baccarani, M.6
  • 49
    • 0034027095 scopus 로고    scopus 로고
    • Preliminary experience of allogeneic stem cell transplantation for lymphoproliferative disease using BEAM-CAMPATH conditioning: an effective regimen with low procedure related toxicity
    • Cull G., Haynes A.P., Byrne J.L., Carter G.I., Miflin G., Rebello P., et al. Preliminary experience of allogeneic stem cell transplantation for lymphoproliferative disease using BEAM-CAMPATH conditioning: an effective regimen with low procedure related toxicity. Br J Haematol 108 (2000) 754-760
    • (2000) Br J Haematol , vol.108 , pp. 754-760
    • Cull, G.1    Haynes, A.P.2    Byrne, J.L.3    Carter, G.I.4    Miflin, G.5    Rebello, P.6
  • 50
    • 3843129540 scopus 로고    scopus 로고
    • Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration
    • Hale G., Rebello P., Brettman L.R., Fegan C., Kennedy B., Kimby E., et al. Blood concentrations of alemtuzumab and antiglobulin responses in patients with chronic lymphocytic leukemia following intravenous or subcutaneous routes of administration. Blood 104 (2004) 948-955
    • (2004) Blood , vol.104 , pp. 948-955
    • Hale, G.1    Rebello, P.2    Brettman, L.R.3    Fegan, C.4    Kennedy, B.5    Kimby, E.6
  • 51
    • 0036683449 scopus 로고    scopus 로고
    • Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
    • Lundin J., Kimby E., Bjorkholm M., Broliden P.A., Celsing F., Hjalmar V., et al. Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood 100 (2002) 768-773
    • (2002) Blood , vol.100 , pp. 768-773
    • Lundin, J.1    Kimby, E.2    Bjorkholm, M.3    Broliden, P.A.4    Celsing, F.5    Hjalmar, V.6
  • 52
    • 0031027623 scopus 로고    scopus 로고
    • Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukemia
    • Bowen A.L., Zomas A., Emmett E., Matutes E., Dyer M.J., and Catovsky D. Subcutaneous CAMPATH-1H in fludarabine-resistant/relapsed chronic lymphocytic and B-prolymphocytic leukemia. Br J Haematol 96 (1997) 617-619
    • (1997) Br J Haematol , vol.96 , pp. 617-619
    • Bowen, A.L.1    Zomas, A.2    Emmett, E.3    Matutes, E.4    Dyer, M.J.5    Catovsky, D.6
  • 53
    • 4243956260 scopus 로고    scopus 로고
    • Varyng modes of maintenance therapy with CAMPATH-1H in chronic lymphocytic leukemia
    • (abstr)
    • Rai K.R., Jonson D., Driscoll N., Crowley A., and Ahmed S. Varyng modes of maintenance therapy with CAMPATH-1H in chronic lymphocytic leukemia. Proc Am Soc Clin Oncol 21 (2002) 275a (abstr)
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Rai, K.R.1    Jonson, D.2    Driscoll, N.3    Crowley, A.4    Ahmed, S.5
  • 54
    • 2942694373 scopus 로고    scopus 로고
    • Consolidation with alemtuzumab in patients with chronic lymphocytic leukemia (CLL) in first remission: Experience on safety and efficacy within a randomized multicenter phase III trial of the German CLL Study Group (GCLLSG)
    • Wendtner C.M., Ritgen M., Schweighofer C.D., Fingerle-Rowson G., Campe H., Jager G., et al. Consolidation with alemtuzumab in patients with chronic lymphocytic leukemia (CLL) in first remission: Experience on safety and efficacy within a randomized multicenter phase III trial of the German CLL Study Group (GCLLSG). Leukemia 18 (2004) 1093-1101
    • (2004) Leukemia , vol.18 , pp. 1093-1101
    • Wendtner, C.M.1    Ritgen, M.2    Schweighofer, C.D.3    Fingerle-Rowson, G.4    Campe, H.5    Jager, G.6
  • 55
    • 0344236261 scopus 로고    scopus 로고
    • Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia
    • O'Brien S.M., Kantarjian H.M., Thomas D.A., Cortes J., Giles F.J., Wierda W.G., et al. Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia. Cancer 98 (2003) 2657-2663
    • (2003) Cancer , vol.98 , pp. 2657-2663
    • O'Brien, S.M.1    Kantarjian, H.M.2    Thomas, D.A.3    Cortes, J.4    Giles, F.J.5    Wierda, W.G.6
  • 56
    • 0035883042 scopus 로고    scopus 로고
    • Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin
    • Linenberger M.L., Hong T., Flowers D., Sievers E.L., Gooley T.A., Bennett M.S., et al. Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin. Blood 98 (2001) 988-994
    • (2001) Blood , vol.98 , pp. 988-994
    • Linenberger, M.L.1    Hong, T.2    Flowers, D.3    Sievers, E.L.4    Gooley, T.A.5    Bennett, M.S.6
  • 57
    • 0035397980 scopus 로고    scopus 로고
    • Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukaemia in first relapse
    • Sievers E.L., Larson R.A., Stadtmauer E.A., Estey E., Lowenberg B., Dombret H., et al. Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukaemia in first relapse. J Clin Oncol 19 (2001) 3244-3254
    • (2001) J Clin Oncol , vol.19 , pp. 3244-3254
    • Sievers, E.L.1    Larson, R.A.2    Stadtmauer, E.A.3    Estey, E.4    Lowenberg, B.5    Dombret, H.6
  • 58
    • 13444253828 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin (Mylotarg) has therapeutic activity against CD33+ acute lymphoblastic leukaemias in vitro and in vivo
    • Golay J., Di Gaetano N., Amico D., Cittera E., Barbui A.M., Giavazzi R., et al. Gemtuzumab ozogamicin (Mylotarg) has therapeutic activity against CD33+ acute lymphoblastic leukaemias in vitro and in vivo. Br J Haematol 128 (2005) 310-317
    • (2005) Br J Haematol , vol.128 , pp. 310-317
    • Golay, J.1    Di Gaetano, N.2    Amico, D.3    Cittera, E.4    Barbui, A.M.5    Giavazzi, R.6
  • 59
    • 0037804758 scopus 로고    scopus 로고
    • Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: Role of Chk1 and Chk2 phosphorylation and caspase 3
    • Amico D., Barbui A.M., Erba E., Rambaldi A., Introna M., and Golay J. Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: Role of Chk1 and Chk2 phosphorylation and caspase 3. Blood 101 (2003) 4589-4597
    • (2003) Blood , vol.101 , pp. 4589-4597
    • Amico, D.1    Barbui, A.M.2    Erba, E.3    Rambaldi, A.4    Introna, M.5    Golay, J.6
  • 60
    • 0033151526 scopus 로고    scopus 로고
    • Selective ablation of acute myeloid leukemia using antibodytargeted chemotherapy: A phase I study of an anti-CD33 calicheamicin immunoconjugate
    • Sievers E.L., Appelbaum F.R., Spielberger R.T., Forman S.J., Flowers D., Smith F.O., et al. Selective ablation of acute myeloid leukemia using antibodytargeted chemotherapy: A phase I study of an anti-CD33 calicheamicin immunoconjugate. Blood 93 (1999) 3678-3684
    • (1999) Blood , vol.93 , pp. 3678-3684
    • Sievers, E.L.1    Appelbaum, F.R.2    Spielberger, R.T.3    Forman, S.J.4    Flowers, D.5    Smith, F.O.6
  • 61
    • 0035397980 scopus 로고    scopus 로고
    • Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse
    • Sievers E.L., Larson R.A., Stadtmauer E.A., Estey E., Lowenberg B., Dombret H., et al. Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse. J Clin Oncol 19 (2001) 3244-3254
    • (2001) J Clin Oncol , vol.19 , pp. 3244-3254
    • Sievers, E.L.1    Larson, R.A.2    Stadtmauer, E.A.3    Estey, E.4    Lowenberg, B.5    Dombret, H.6
  • 62
    • 33845526373 scopus 로고    scopus 로고
    • High efficacy and safety profile of fractionated doses of Mylotarg as induction therapy in patients with relapsed acute myeloblastic leukemia: A prospective study of the Alfa group
    • Taksin A.L., Legrand O., Raffoux E., de Revel T., Thomas X., Contentin N., et al. High efficacy and safety profile of fractionated doses of Mylotarg as induction therapy in patients with relapsed acute myeloblastic leukemia: A prospective study of the Alfa group. Leukemia 21 (2007) 66-71
    • (2007) Leukemia , vol.21 , pp. 66-71
    • Taksin, A.L.1    Legrand, O.2    Raffoux, E.3    de Revel, T.4    Thomas, X.5    Contentin, N.6
  • 63
    • 0035874504 scopus 로고    scopus 로고
    • Targeting of the CD33- calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: In vivo and in vitro saturation and internalization by leukemic and normal myeloid cells
    • van der Velden V.H.J., te Marvelde J.G., Hoogeveen P.G., Bernstein I.D., Houtsmuller A.B., Berger A.S., et al. Targeting of the CD33- calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: In vivo and in vitro saturation and internalization by leukemic and normal myeloid cells. Blood 97 (2001) 3197-3204
    • (2001) Blood , vol.97 , pp. 3197-3204
    • van der Velden, V.H.J.1    te Marvelde, J.G.2    Hoogeveen, P.G.3    Bernstein, I.D.4    Houtsmuller, A.B.5    Berger, A.S.6
  • 64
    • 0034770328 scopus 로고    scopus 로고
    • Pharmacokinetics of gemtuzumab ozogamicin, an antibody-targeted chemotherapy agent for the treatment of patients with acute myeloid leukemia in first relapse
    • Dowell J.A., Korth-Bradley J., Liu H., King S.P., and Berger M.S. Pharmacokinetics of gemtuzumab ozogamicin, an antibody-targeted chemotherapy agent for the treatment of patients with acute myeloid leukemia in first relapse. J Clin Pharmacol 41 (2001) 1206-1214
    • (2001) J Clin Pharmacol , vol.41 , pp. 1206-1214
    • Dowell, J.A.1    Korth-Bradley, J.2    Liu, H.3    King, S.P.4    Berger, M.S.5
  • 65
    • 34249748062 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin (Mylotargs) as single agent treatment for adult patients with acute myeloid leukemia (AML)
    • (abstr)
    • Thomas X., Le Q.H., Tavernier E., Mahmoudi S., Chelghoum Y., Nicolini F., et al. Gemtuzumab ozogamicin (Mylotargs) as single agent treatment for adult patients with acute myeloid leukemia (AML). Blood 106 (2005) 4598 (abstr)
    • (2005) Blood , vol.106 , pp. 4598
    • Thomas, X.1    Le, Q.H.2    Tavernier, E.3    Mahmoudi, S.4    Chelghoum, Y.5    Nicolini, F.6
  • 66
    • 0036733277 scopus 로고    scopus 로고
    • Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin)
    • Larson R.A., Boogaerts M., Estey E., Karanes C., Stadtmauer E.A., Sievers E.L., et al. Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin). Leukemia 16 (2002) 1627-1636
    • (2002) Leukemia , vol.16 , pp. 1627-1636
    • Larson, R.A.1    Boogaerts, M.2    Estey, E.3    Karanes, C.4    Stadtmauer, E.A.5    Sievers, E.L.6
  • 67
    • 0031757274 scopus 로고    scopus 로고
    • CAMPATH-1H monoclonal antibody in therapy for previous treated low-grade non-Hodgkin's lymphomz: A phase II multicenter study
    • Lundin J., Österborg A., Brittinger G., Crowther D., Dombret A., Engert A., et al. CAMPATH-1H monoclonal antibody in therapy for previous treated low-grade non-Hodgkin's lymphomz: A phase II multicenter study. J Clin Oncol 16 (1998) 3257-3262
    • (1998) J Clin Oncol , vol.16 , pp. 3257-3262
    • Lundin, J.1    Österborg, A.2    Brittinger, G.3    Crowther, D.4    Dombret, A.5    Engert, A.6
  • 68
    • 0036076178 scopus 로고    scopus 로고
    • Safety and efficacy of subcutaneous Campath-1H for treating residual disease in patients with chronic lymphocytic leucemia responding to fludarabine
    • Montillo M., Cafro A.M., Tedeschi A., Brando B., Oreste P., Veronese S., et al. Safety and efficacy of subcutaneous Campath-1H for treating residual disease in patients with chronic lymphocytic leucemia responding to fludarabine. Haematologica 87 (2002) 695-700
    • (2002) Haematologica , vol.87 , pp. 695-700
    • Montillo, M.1    Cafro, A.M.2    Tedeschi, A.3    Brando, B.4    Oreste, P.5    Veronese, S.6
  • 69
    • 21144456107 scopus 로고    scopus 로고
    • Eradication of minimal residual disease in B-cell chronic lymhocytic leukemia after alemtuzumab therapy is associated with prolonged survival
    • Moreton P., Kennedy B., Lucas G., Leach M., Rassam S.M.B., Haynes A., et al. Eradication of minimal residual disease in B-cell chronic lymhocytic leukemia after alemtuzumab therapy is associated with prolonged survival. J Clin Oncol 23 (2005) 2971-2979
    • (2005) J Clin Oncol , vol.23 , pp. 2971-2979
    • Moreton, P.1    Kennedy, B.2    Lucas, G.3    Leach, M.4    Rassam, S.M.B.5    Haynes, A.6
  • 70
    • 3242886035 scopus 로고    scopus 로고
    • Gemtuzumeb ozogamicin for relapsed and refractory acute myeioid leukemia and myeloid sarcomas
    • Piccaluga P.P., Martinelli G., Rondoni M., Malagola M., Gaitani S., Isidori A., et al. Gemtuzumeb ozogamicin for relapsed and refractory acute myeioid leukemia and myeloid sarcomas. Leuk Lymphoma 45 (2004) 1791-1795
    • (2004) Leuk Lymphoma , vol.45 , pp. 1791-1795
    • Piccaluga, P.P.1    Martinelli, G.2    Rondoni, M.3    Malagola, M.4    Gaitani, S.5    Isidori, A.6
  • 71
    • 25144485908 scopus 로고    scopus 로고
    • Final report of the efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myelcid leukemia in first recurrence
    • Larson R.A., Sievers E.L., Stadtmauer E.A., Lowenberg B., Estey E.H., Dombret H., et al. Final report of the efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myelcid leukemia in first recurrence. Cancer 104 (2005) 1442-1452
    • (2005) Cancer , vol.104 , pp. 1442-1452
    • Larson, R.A.1    Sievers, E.L.2    Stadtmauer, E.A.3    Lowenberg, B.4    Estey, E.H.5    Dombret, H.6
  • 72
    • 27144464151 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin as single-agent treatment for frail patients 61 years of age and older with acute myeloid leukemia: Final results of AML-15B, a phase 2 study of the European Organisation for Research and Treatment of Cancer and Gruppo Italiano Malattie Ematologiche dell'Adulto Leucemia Groups
    • Amadori S., Suciu S., Stasi R., Willemze R., Mandelli F., Sellesiag D., et al. Gemtuzumab ozogamicin as single-agent treatment for frail patients 61 years of age and older with acute myeloid leukemia: Final results of AML-15B, a phase 2 study of the European Organisation for Research and Treatment of Cancer and Gruppo Italiano Malattie Ematologiche dell'Adulto Leucemia Groups. Leukemia 19 (2005) 1768-1773
    • (2005) Leukemia , vol.19 , pp. 1768-1773
    • Amadori, S.1    Suciu, S.2    Stasi, R.3    Willemze, R.4    Mandelli, F.5    Sellesiag, D.6
  • 73
    • 8444224241 scopus 로고    scopus 로고
    • Phase II pilot trial of gemtuzumab ozogamicin (GO) as first line therapy in acute myeloid leukemia patients age 65 or older
    • Nebhan C., Rundhaugen L.M., Riley M.B., Rademaker A., Boehike L., Jatoi M., et al. Phase II pilot trial of gemtuzumab ozogamicin (GO) as first line therapy in acute myeloid leukemia patients age 65 or older. Leuk Res 29 (2005) 53-57
    • (2005) Leuk Res , vol.29 , pp. 53-57
    • Nebhan, C.1    Rundhaugen, L.M.2    Riley, M.B.3    Rademaker, A.4    Boehike, L.5    Jatoi, M.6
  • 74
    • 33645724208 scopus 로고    scopus 로고
    • Efficacy and toxicity of gemtuzumab ozogamicin in patients with acute myeloid leukemia
    • Van der Heiden P.L., Jedema I., Willemze R., and Barge R.M. Efficacy and toxicity of gemtuzumab ozogamicin in patients with acute myeloid leukemia. Eur J Haematol 76 (2006) 409-413
    • (2006) Eur J Haematol , vol.76 , pp. 409-413
    • Van der Heiden, P.L.1    Jedema, I.2    Willemze, R.3    Barge, R.M.4


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