α-amino-3-hydroxy-5-methyl-4-isoxazole propionate attenuates glutamate-induced caspase-3 cleavage via regulation of glycogen synthase kinase 3β

Journal of Neuroscience Research

Volumn 86, Issue 5, 2008, Pages 1096-1105

  Nishimoto, Takaaki ^a   Kihara, Takeshi ^a   Akaike, Akinori ^a   Niidome, Tetsuhiro ^a   Sugimoto, Hachiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; Glutamate receptor; Ischemia; Neuroprotection

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CASPASE 3; CASPASE 3 INHIBITOR; CYSTEINE PROTEINASE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME REGULATION; EXCITOTOXICITY; FETUS; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; BINDING SITES; BRAIN ISCHEMIA; CASPASE 3; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; GLYCOGEN SYNTHASE KINASE 3; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, AMPA; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 41149138934     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21567     Document Type: Article

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