Making sense of the porphyrias

Photodermatology Photoimmunology and Photomedicine

Volumn 24, Issue 2, 2008, Pages 102-108

  Sarkany, Robert P E ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Porphyria; Porphyrin

Indexed keywords

BETA CAROTENE; CHLOROQUINE; COPROPORPHYRIN; HEXACHLOROBENZENE; METHOXSALEN; ORAL CONTRACEPTIVE AGENT; PORPHYRIN; PROTOPORPHYRIN; SINGLET OXYGEN; SUNSCREEN; UROPORPHYRIN; UROPORPHYRINOGEN DECARBOXYLASE;

ARTICLE; BLISTER; CLINICAL FEATURE; CLINICAL TRIAL; CONGENITAL ERYTHROPOIETIC PORPHYRIA; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG MEGADOSE; FOLLOW UP; HEREDITY; HORMONE SUBSTITUTION; HUMAN; LIVER NECROSIS; LOW DRUG DOSE; PATHOGENESIS; PHLEBOTOMY; PHOTOSENSITIVITY; PHOTOTHERAPY; PHOTOTOXICITY; PORPHYRIA CUTANEA TARDA; PORPHYRIA VARIEGATA; PRIORITY JOURNAL; PUVA; RISK FACTOR; SKIN EDEMA; SKIN FRAGILITY; SKIN NECROSIS; SKIN PAIN; SKIN PROTECTION; SUN EXPOSURE;

HUMANS; PORPHYRIAS; SKIN DISEASES;

EID: 41149124539     PISSN: 09054383     EISSN: 16000781     Source Type: Journal    
DOI: 10.1111/j.1600-0781.2008.00336.x     Document Type: Article

References (19)

1. Wilkins PC, Wilkins RG. Inorganic Chemistry in Biology. Oxford: Oxford University Press, 1997.
2. Elder GH. The cutaneous porphyrias. In: Hawk JLM, ed. Photodermatology. London: Arnold, 1999; 171-199.
3. Brun A, Sandberg S. Mechanisms of photosensitivity in porphyric patients with special emphasis on erythropoietic protoporphyria. J Photochem Photobiol B 1991; 10: 285-302.
4. Takeshita K, Takajo T, Hirata H, Ono M, Utsumi H. In vivo oxygen radical generation in the skin of the protoporphyria model mouse with visible light exposure: An L-band ESR study. J Invest Dermatol 2004; 122: 1463-1470.
5. Meyer-Betz F. Untersuchungen über die biologische (photodynamische) Wirkung des Hämatoporphyrins und anderer Derivate des Blut- und Gallenfarbstoffs. Deutsch Arch Klin Med 1913; 112: 476-503.
6. Caputo R, Berti E, Gasparini G, Monti M. The morphologic events of blister formation in porphyria cutanea tarda. Int J Dermatol 1983; 22: 467-472.
7. Sarkany RPE. The cutaneous porphyrias. In: Burns T, et al., eds. Rook's textbook of dermatology, 7th Edn. Oxford: Blackwell, 2004; 57.1-57.23.
8. Bulaj ZJ, Phillips JD, Ajioka RS, et al. Hemochromatosis genes and other factors contributing to the pathogenesis of porphyria cutanea tarda. Blood 2000; 95: 1565-1571.
9. Elder GH, Hift RJ, Meissner PN. The acute porphyrias. Lancet 1997; 349: 1613-1617.
10. http://www.porphyria-europe.com
11. Bruguera M. Liver involvement in porphyria. Semin Dermatol 1986; 5: 178-185.
12. Sarkany RPE, Cox TM. Autosomal recessive erythropoietic protoporphyria: a syndrome of severe photosensitivity and hepatic failure. Q J Med 1995; 88: 541-549.
13. Long C, Smyth SJ, Woolf J, et al. Detection of latent variegate porphyria by fluorescence emission spectroscopy of plasma. Br J Dermatol 1993; 129: 9-13.
14. Gouya L, Martin-Schmitt C, Robreau AM, Austerlitz F, Da Silva V, Simonin S, Lyoumi S, Grandchamp B, Beaumont C, Puy H, Deybach JC. Contribution of a common single-nucleotide polymorphism to the genetic predisposition for erythropoietic protoporphyria. Am J Hum Genet 2006; 78: 2-14.
15. Sarkany RP. The management of porphyria cutanea tarda. Clin Exp Dermatol 2001; 26: 225-232. Review.
16. Moseley H, Cameron H, MacLeod T, et al. New sunscreens confer improved protection for photosensitive patients in the blue light region. Br J Dermatol 2001; 145: 789-794.
17. Elder GH. Alcohol intake and PCT. Clin Dermatol 1999; 17: 431-436.
18. Dean G. The Turkish epidemic of porphyria. In: Dean G, ed. The porphyrias: A story of inheritance and environment, 2nd Edn. London: Pitman Medical, 1971; 67-72.
19. http://plantpathology.tamu.edu/Texlab/Grains/Wheat/Images/wheat7.jpeg.