Tumor necrosis factor-α, interleukin-10, and α-defensins in plasma and breast milk of HIV-infected highly active antiretroviral therapy-treated and untreated pregnant women in Mozambique

Journal of Acquired Immune Deficiency Syndromes

Volumn 47, Issue 5, 2008, Pages 647-649

  Baroncelli, Silvia ^a   Andreotti, Mauro ^a   Guidotti, Giovanni ^a   Pirillo, Maria F ^a   Ceffa, Susanna ^b,c   Mancini, Maria Grazia ^a   Germano, Paola ^b   Marazzi, Maria Cristina ^d   Vella, Stefano ^a   Palombi, Leonardo ^e   Giuliano, Marina ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b DREAM Program ^*  (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d LUMSA UNIVERSITY   (Italy)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DEFENSIN; INTERLEUKIN 10; LAMIVUDINE PLUS NEVIRAPINE PLUS STAVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS ZIDOVUDINE; TUMOR NECROSIS FACTOR ALPHA;

BREAST MILK; CLINICAL ARTICLE; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETTER; MOZAMBIQUE; PLASMA; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL;

ALPHA-DEFENSINS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; DISEASE TRANSMISSION, HORIZONTAL; FEMALE; HIV; HIV INFECTIONS; HUMANS; INTERLEUKIN-10; MILK, HUMAN; MOZAMBIQUE; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 41149124396     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31815f3c4c     Document Type: Letter

References (9)

1. Rousseau CM, Nduati RW, Richardson BA, et al. Association of levels of HIV-1-infected breast milk cells and risk of mother-to-child transmission. J Infect Dis. 2004;190:1880-1888.
2. Koulinska IN, Villamor E, Chaplin B, et al. Transmission of cell-free and cell-associated HIV-1 through breast-feeding. J Acquir Immune Defic Syndr. 2006;41:93-99.
3. Lawn SD. AIDS in Africa: the impact of coinfections on the pathogenesis of HIV-1 infection. J Infect. 2004;48:1-12.
4. Kuhn L, Trabattoni D, Kankasa C, et al. Alpha-defensins in the prevention of HIV transmission among breastfed infants. J Acquir Immune Defic Syndr. 2005;39:138-142.
5. Lohman BL, Slyker J, Mbori-Ngacha D, et al. Prevalence and magnitude of human immunodeficiency virus (HIV) type 1-specific lymphocyte responses in breast milk from HIV-1-seropositive women. J Infect Dis. 2003;188:1666-1674.
6. Giuliano M, Guidotti G, Andreotti M, et al. Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program. J Acquir Immune Defic Syndr. 2007;44:286-291.
7. Hawkes JS, Bryan DL, Gibson RA. Cytokine production by human milk cells and peripheral blood mononuclear cells from the same mothers. J Clin Immunol. 2002;22:338-344.
8. Jarvinen KM, Laine S, Suomalainen H. Defective tumour necrosis factor-alpha production in mother's milk is related to cow's milk allergy in suckling infants. Clin Exp Allergy. 2000;30:637-643.
9. Bosire R, John-Stewart GC, Mabuka JM, et al. Breast milk alpha-defensins are associated with HIV type 1 RNA and CC chemokines in breast milk but not vertical HIV type 1 transmission. AIDS Res Hum Retroviruses. 2007;23:198-203.