In vitro and in vivo evaluation of paralytic shellfish poisoning toxin potency and the influence of the pH of extraction

Analytical Chemistry

Volumn 80, Issue 5, 2008, Pages 1770-1776

  Vale, Carmen ^a   Alfonso, Amparo ^a   Vieytes, Mercedes R ^b   Romarís, Xosé Manuel ^c   Arévalo, Fabiola ^c   Botana, Ana M ^b   Botana, Luis M ^a  

^a Facultad de Veterinaria   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c INTECMAR Technological Institute for the Monitoring of the Marine Environment in Galicia   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DECARBAMOYLSAXITOXIN (DCSTX); FOOD POISONING; PARALYTIC SHELLFISH POISONING (PSP);

BINDING SITES; BIOACTIVITY; FOOD PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PH EFFECTS;

TOXIC MATERIALS;

DECARBAMOYLNEOSAXITOXIN; DECARBAMOYLSAXITOXIN; GONYAUTOXIN; GONYAUTOXIN 1; GONYAUTOXIN 4; GONYAUTOXIN 5; GONYAUTOXIN II; GONYAUTOXIN III; NEOSAXITOXIN; SAXITOXIN; SHELLFISH TOXIN; UNCLASSIFIED DRUG;

ACIDITY; ANIMAL CELL; ARTICLE; BIOASSAY; CHEMICAL MODIFICATION; CONTROLLED STUDY; EXTRACTION; FOOD POISONING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PARALYTIC SHELLFISH POISONING; PH; TOXICITY TESTING; TOXIN ANALYSIS;

ANIMALS; BIOLOGICAL ASSAY; BIVALVIA; CELLS, CULTURED; CEREBELLUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAT; HYDROGEN-ION CONCENTRATION; MARINE TOXINS; MEMBRANE POTENTIALS; MICE; NEURONS; SHELLFISH;

EID: 41149117509     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac7022266     Document Type: Article

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