Light to moderate alcohol consumption is associated with S100β and amyloid beta levels in healthy older adults

Experimental Aging Research

Volumn 34, Issue 2, 2008, Pages 101-113

  Keary, Therese A ^a   Gunstad, John ^a   Neal, Dan J ^a,b   Spitznagel, Mary Beth ^a,b   Glickman, Ellen ^a   Juvancic Heltzel, Judi ^a   Alexander, Thomas ^b  

^a KENT STATE UNIVERSITY   (United States)

^b SUMMA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BIOLOGICAL MARKER; PROTEIN S100B;

AGED; ALCOHOL CONSUMPTION; ARTICLE; FEMALE; FEVER; HEADACHE; HUMAN; MALE; NEUROPATHOLOGY; NEUROPSYCHOLOGICAL TEST; NORMAL HUMAN; PROTEIN BLOOD LEVEL; QUANTITATIVE ASSAY; RISK ASSESSMENT; RISK FACTOR;

AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; AMYLOID BETA-PROTEIN; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; S100 PROTEINS; SAMPLING STUDIES;

EID: 41149103968     PISSN: 0361073X     EISSN: 10964657     Source Type: Journal    
DOI: 10.1080/03610730701876920     Document Type: Article

References (45)

1. Banks, W. & Kastin, A. (1993). The potential for alcohol to affect the passage of peptide and protein hormones across the blood-brain barrier: A hypothesis for a disturbance in brain-body communication. In S. Zakhari (Ed.), NIAAA research monograph 23, alcohol and the endocrine system (pp. 401-411). Bethesda, MD: National Institutes of Health: National Institute on Alcohol Abuse and Alcoholism.
2. Brown, S. A., Tapert, S. F., Granholm, E., & Delis, D. C. (2000). Neurocognitive functioning of adolescents: Effects of protracted alcohol use. Alcoholism: Clinical and Experimental Research, 24, 164-171.
3. Cargiulo, T. (2007). Understanding the health impact of alcohol dependence. American Journal of Health-System Pharmacy, 64, S5-S11.
4. Cohen, J. (1992). A power primer. Psychological Bulletin, 112, 155-159.
5. Connolly, E. S., Jr., Winfree, C. J., Rampersad, A., Sharma, R., Mack, W. J., Solomon, R. A., et al. (2001). Serum S100B protein levels are correlated with subclinical neurocognitive declines after carotid endarterectomy. Neurosurgery, 49, 1076-1083.
6. Ding, J., Eigenbrodt, M. L., Mosley, T. H., Hutchinson, R. G., Folsom, A. R., Harris, T. B., et al. (2004). Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community-based population of middle-aged adults. Stroke, 35, 16-21.
7. Espeland, M. A., Coker, L. H., Wallace, R., Rapp, S. R., Resnick, S. M., Limacher, M., et al. (2006). Association between alcohol intake and domain-specific cognitive function in older women. Neuroepidemiology, 27, 1-12.
8. Ezzati, M., Lopez, A. D., Rodgers, A., Vander Hoorn, S., Murray, C. J. L., & Comparative Risk Assessment Collaborating Group. (2002). Selected major risk factors and global and regional burden of disease. Lancet, 360, 1347-1360.
9. Fein, G., Torres, J., Price, L. J., & DiSclafani, V. (2006). Cognitive performance in long-term abstinent alcoholic individuals. Alcoholism: Clinical and Experimental Research, 30, 1538-1544.
10. Ganguli, M., Vander Bilt, J., Saxton, J. A., Shen, C., & Dodge, H. H. (2005). Alcohol consumption and cognitive function in late life: A longitudinal community study. Neurology, 65, 1210-1217.
11. Glasgow, R. E., Ory, M. G., Klesges, L. M., Cifuentes, M., Fernald, D. H., & Green, L. A. (2005). Practical and relevant self-report measures of patient health behaviors for primary care research. Annals of Family Medicine, 3, 73-81.
12. Gutjahr, E., Gmel, G., & Rehm, J. (2001). Relationship between average alcohol consumption and disease: An overview. European Addiction Research, 2001, 7, 117-127.
13. Hartley, D. E., Elsabagh, S., & File, S. E. (2004). Binge drinking and sex: Effects on mood and cognitive function in healthy young volunteers. Pharmacology, Biochemistry, and Behavior, 78, 611-619.
14. Kanner, A. A., Marchi, N., Fazio, V., Mayberg, M. R., Koltz, M. T., Siomin, V., et al. (2003). Serum S100B: A noninvasive marker of blood-brain function and brain lesions. Cancer, 97, 2806-2813.
15. Kornhuber, J., Kaiserauer, C. H., Kornhuber, A. W., & Kornhuber, M. E. (1987). Alcohol consumption and blood-cerebrospinal fluid barrier dysfunction in man. Neuroscience Letters, 79, 218-222.
16. Kornreich, C., Philippot, P., Foisy, M.-L., Blairy, S., Reynaud, E., Dan, B., et al. (2002). Impaired emotional facial expression recognition is associated with interpersonal problems in alcoholism. Alcohol and Alcoholism, 37, 394-400.
17. Krahn, D., Freese, J., Hauser, R., Barry, K., & Goodman, B. (2003). Alcohol use and cognition at mid-life: The importance of adjusting for baseline cognitive ability and educational attainment. Alcoholism: Clinical and Experimental Research, 27, 1162-1166.
18. Lang, I., Wallace, R. B., Huppert, F. A., & Melzer, D. (2007). Moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence. Age and Ageing, 36, 256-261.
19. Mannelli, P. & Pae, C. U. (2007). Medical comorbidity and alcohol dependence. Current Psychiatry Reports, 9, 217-224.
20. Marchi, N., Cavaglia, M., Fazio, V., Bhudia, S., Hallene, K., & Janigro, D. (2004). Peripheral markers of blood-brain barrier damage. Clinica Chimica Acta, 342, 1-12.
21. McGuire, L. C., Ajani, U. A., & Ford, E. S. (2007). Cognitive functioning in late life: The impact of moderate alcohol consumption. Annals of Epidemiology, 17, 93-99.
22. Moore, A. A., Whiteman, E. J., & Ward, K. T. (2007). Risks of combined alcohol/medication use in older adults. American Journal of Geriatric Psychopharmacology, 5, 64-74.
23. Ngandu, T., Helkala, E. L., Soininen, H., Winblad, B., Tuomilehto, J., Nissinen, A., et al. (2007). Alcohol drinking and cognitive functions: Findings from the Cardiovascular Risk Factors Aging and Dementia (CAIDE) Study. Dementia and Geriatric Cognitive Disorders, 23, 140-149.
24. Pan, W., Barron, M., Hsuchou, H., Tu, H., & Kastin, A. J. (2007). Increased leptin permeation across the blood-brain barrier after chronic alcohol ingestion. Neuropsychopharmacology, Epub ahead of print.
25. Parsons, O. A. (1998). Neurocognitive deficits in alcoholics and social drinkers: A continuum. Alcoholism: Clinical and Experimental Research, 22, 954-961.
26. Pascual, M., Blanco, A. M., Cauli, O., Mi~narro, J., & Guerri, C. (2007). Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats. European Journal of Neuroscience, 25, 541-550.
27. Peskind, E. R., Griffin, S. T., Akama, K. T., Raskind, M. A., & Van Eldik, L. J. (2001). Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease. Neurochemistry International, 39, 409-413.
28. Pfefferbaum, A., Sullivan, E. V., Mathalon, D. H., & Lim, K. O. (1997). Frontal lobe volume loss observed with magnetic resonance imaging in older chronic alcoholics. Alcoholism: Clinical and Experimental Research, 21, 521-529.
29. Rehm, J., Gmel, G., Sempos, C. T., & Trevisan, M. (2002). Alcohol-related morbidity and mortality. Alcohol Research and Health, 27, 39-51.
30. Rehm, J., Room, R., Graham, K., Monteiro, M., Gmel, G., & Sempos, C. T. (2003). The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: An overview. Addiction, 98, 1209-1228.
31. Reid, M. C., Van Ness, P. H., Hawkins, K. A., Towle, V., Concato, J., & Guo, Z. (2006). Light to moderate alcohol consumption is associated with better cognitive function among older male veterans receiving primary care. Journal of Geriatric Psychiatry and Neurology, 19, 98-105.
32. Room, R., Babor, T., & Rehm, J. (2005). Alcohol and public health. Lancet, 365, 519-530.
33. Selkoe, D. J. (1999). Translating cell biology into therapeutic advances in Alzheimer's disease. Nature, 399, A23-A31.
34. Singh, A. K., Jiang, Y., Gupta, S., & Benlhabib, E. (2007). Effects of chronic ethanol drinking on the blood-brain barrier and ensuing neuronal toxicity in alcohol-preferring rats subjected to intraperitoneal LPS injection. Alcohol and Alcoholism, 42, 386-399 (Epub ahead of print).
35. Snyder-Ramos, S. A., Gruhlke, T., Bauer, H., Bauer, M., Luntz, A. P., Motsch, J. et al. (2004). Cerebral and extracerebral release of protein S100B in cardiac surgical patients. Anaesthesia, 59, 344-349.
36. Sobell, L. C. & Sobell, M. B. (2000). Alcohol Timeline Followback (TFLB). In American Psychiatric Association (Ed.), Handbook of psychiatric measures (pp. 477-479). Washington, DC: American Psychiatric Association.
37. Solfrizzi, V., D'Introno, A., Colaciccio, A. M., Capurso, C., Del Parigi, A., Baldasarre, G., et al. (2007). Alcohol consumption, mild cognitive impairment, and progression to dementia. Neurology, 68, 1790-1799.
38. Spitznagel, M. B., Gunstad, J., Glickman, E., Alexander, T., Juvancic-Heltzel, J., Walter, K., et al. (2007). Serum amyloid beta is associated with reduced cognitive function in healthy older adults. Unpublished Work.
39. Sullivan, E. V., Rosenbloom, M. J., & Pfefferbaum, A. (2000). Pattern of motor and cognitive deficits in detoxified alcoholic men. Alcoholism: Clinical and Experimental Research, 24, 611-621.
40. Suzuki, Y., Oishi, M., Mizutani, T., & Sato, Y. (2002). Regional cerebral blood flow measured by the resting and vascular reserve (RVR) method in chronic alcoholics. Alcoholism: Clinical and Experimental Research, 26, 95s-99s.
41. Tamaoka, A., Fukushima, T., Sawamura, N., Ishikawa, K., Oguni, E., Komatsuzaki, Y., et al. (1996). Amyloid â protein in plasma from patients with sporadic Alzheimer's disease. Journal of the Neurological Sciences, 151, 65-68.
42. Townschend, J. M. & Duka, T. (2005). Binge drinking, cognitive performance and mood in a population of young social drinkers. Alcoholism: Clinical and Experimental Research, 29, 317-325.
43. Vincze, G., Almos, P., Boda, K., Döme, P., Bodi, N., Szlávik, G. et al. (2007). Risk factors of cognitive decline in residential care in Hungary. International Journal of Geriatric Psychiatry, 22, 1208-1216. (Epub ahead of print).
44. Vogelbaum, M. A., Masaryk, T., Mazzone, P., Mekhail, T., Fazio, V., McCartney, S., et al. (2005). S100b as a predictor of brain metastases. Cancer, 104, 817-824.
45. Zuccalà, G., Onder, G., Pedone, C., Cesari, M., Landi, F., Bernabei, R., et al. (2001). Dose-related impact of alcohol consumption on cognitive function in advanced age: Results of a multicenter survey. Alcohol and Alcoholism, 25, 1743-1748.