An in vitro evaluation of fenugreek mucilage as a potential excipient for oral controlled-release matrix tablet

Drug Development and Industrial Pharmacy

Volumn 34, Issue 3, 2008, Pages 323-329

  Nokhodchi, Ali ^a   Nazemiyeh, Hossein ^b,c   Khodaparast, Afagh ^b   Sorkh Shahan, Tarifeh ^b   Valizadeh, Hadi ^b   Ford, J L ^d  

^a MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

^b TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

Fenugreek mucilage; Mechanism of release; Propranolol hydrochloride; Release rate

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; PROPRANOLOL; WATER;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED RELEASE FORMULATION; DIFFUSION; EVALUATION; FENUGREEK; KINETICS; MATRIX TABLET; MUCILAGE;

ADHESIVES; ADMINISTRATION, ORAL; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; KINETICS; LACTOSE; METHYLCELLULOSE; PROPRANOLOL; SOLUBILITY; TABLETS; TRIGONELLA; VISCOSITY;

EID: 41149086759     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701662594     Document Type: Article

References (29)

1. Al-Habori M. A. (2002). Pharmacological properties. In G. A. Petropoulus (Ed.), Fenugreek: The genus Trigonella (pp. 162-163). London: Taylor and Francis.
2. Baveja, S. K., & Ranga Rao, K. V. (1986). Sustained release tablet formulations of centperazine. Int. J. Pharm., 31, 169-174.
3. Bonferoni, M. C., Rossi, S., Tamayo, M., Pedraz, J.L., Dominguez-Gil, A., Caramella, C. (1993). On the employment of lcarrageenan in a matrix system. I. Sensitivity to dissolution medium and comparison with Na carboxymethylcellulose and xanthan gum. J. Control. Release, 26, 119-127.
4. Colombo, P., Bettini, R., Massimo, G., Catellani, P. L., Santi, P., & Peppas, N. A. (1995). Drug diffusion front movement is important in drug release control from swellable matrix tablets. J. Pharm. Sci., 84, 991-997.
5. Colombo, P., Conte, U., Caramella, C., Gazzaniga, A., & La Manna, A. (1985). Compressed polymeric mini-matrices for drug release control. J Control. Release, 1, 283-289.
6. Costa, F. O., Sousa, J. J. S., Pais, A. A. C. C., & Formosinho, S. J. (2003). Comparison of dissolution profiles of Ibuprofen pellets. J. Control. Rel., 89, 199-212.
7. Ford, J. L., Mitchell, K., Rowe, P., Armstrong, D. J., Elliott, P. N. C., Rostron, C., & Hogan, J. E. (1991). Mathematical modelling of drug release from hydroxypropylmethylcellulose matrices: Effect of temperature. Int. J. Pharm., 71, 95-104.
8. Ford, J. L., Rubinstein, M. H., & Hogan, J. E. (1985). Formulation of sustained release promethazine hydrochloride tablets using hydroxypropylmethyl cellulose. Int. J. Pharm., 24, 327-338.
9. Ford, J. L., Rubinstein, M. H., McCaul, F., Hogan, J. E., & Edgar, P. J. (1987). Importance of drug type, tablet shape and added diluents on drug release kinetics from hydroxypropylmethylcellulose matrix tablets. Int. J. Pharm., 40, 223-234.
10. Gao P., & Fagerness P. E. (1995). Diffusion in hydroxypropylmethylcellulose gels. Part 1. Determination of drug and water diffusivity by pulsed field gradient spin echo NMR, Pharm. Res., 12, 955-964.
11. Harborne, J. B. (1998). Sugars and their derivatives. In, Phytochemical methods: A guide to modern techniques of plant analysis (3 ed.; pp. 235-290). London: Chapman & Hall.,
12. Hussain, A. S., Johnson, R. D., Shivanand, P., & Zoglio, M. A. (1994). Effects of blending a nonionic and an anionic cellulose ether polymer on drug release from hydrophilic matrix capsules. Drug Dev. Ind. Pharm., 20, 2645-2657.
13. Karawya, M. S. (1980). Mucilagenous contents of certain Egyption plants. Planta Medica, 38, 73-78.
14. Khan, K. A. (1975). Concept of dissolution efficiency. J. Pharm. Pharmacol., 27, 48-49.
15. Khullar, P., Khar, R. K., & Agarwal, S. P. (1998). Evaluation of guar gum in the preparation of sustained-release matrix tablets. Drug Dev. Ind. Pharm., 24, 1095-1099.
16. Korsmeyer, R. W., Gurny, R., Doelker, E., Buri, P., & Peppas, N. A. (1983). Mechanisms of solute release from porous hydrophilic polymers. Int. J. Pharm., 15, 25-35.
17. Kristmundsottir, T., Ingvarsdottir, K., & Sæmundsdottir, G. (1995) Chitosan matrix tablets: The influence of excipients on drug release. Drug Dev. Ind. Pharm., 21, 1591-1598.
18. Lapidus, H., & Lordi, N. G. (1988). Some factors affecting the release of water soluble drug form a compressed hydrophilic matrix. J. Pharm. Sci., 55, 840-843.
19. Li, C. L., Martini, L. G., Ford, J. L., & Roberts, M. (2005). The use of hypomellose in oral drug delivery. J. Pharm. Pharmacol., 57, 533-546.
20. Mockel, J. E., & Lippold, B. C. (1993). Zero-order drug release from hydrocolloid matrices. Pharm. Res., 10, 1066-1070.
21. Munday, D. L., & Cox. P. J. (2000). Compressed xanthan and karaya gum matrices: Hydration, erosion and drug release mechanism. Int. J. Pharm., 203, 179-192.
22. Naggar, V. F., El-Khawas, M., Ismail, F. A., & Boraie, N. A., (1992). Pectin, a possible matrix for oral sustained-release preparations of water-soluble drugs. STP Pharma. Sci., 2, 227-234.
23. Nakano, M., & Ogata, A., (1984). Examination of natural gums as matrices for sustained release of theophylline. Chem. Pharm. Bull., 32, 782-785.
24. Petropoulos, G. A., (2002). Botany. In G. A. Petropoulus (Ed.) Fenugreek: The genus Trigonella (pp. 9-17). London: Taylor and Francis.
25. Peppas, N. A. (1985). Analysis of fickian and non-fickian drug release from polymers. Pharm. Acta Helv., 60, 110-111.
26. Ranga Rao, K. V., Padmalatha Devi, P., & Buri, P. (1990). Influence of molecular size and water solubility of the solute on its release from swelling and erosion controlled polymeric matrices. J. Controlled Release, 12, 133-141.
27. Reynolds, T. D., Gehrke, S. H., Hussain, A. S., & Shenouda, L. S. (1998). Polymer erosion and drug release characterisation of hydroxypropylmethylcellulose matrices. J. Pharm. Sci. 87, 1115-1123.
28. Ughini, F., Andreazza, I. F., Ganter, J. L. M. S., & Bresolin, T. M. B. (2004). Evaluation of xanthan and highly substituted galactomannan from M. scabrella as a sustained release matrix. Int. J. Pharm., 271, 197-205.
29. Vervoort, L., Van den Mooter, G., Augustijns, P., & Kinget, R. (1998). Inulin hydrogels. I. Dynamic and equilibrium swelling properties. Int. J. Pharm., 172, 127-135.