Ovarian failure in SLE patients using pulse cyclophosphamide: Comparison of different regimes

Rheumatology International

Volumn 28, Issue 6, 2008, Pages 567-571

  Appenzeller, Simone ^a,b   Blatyta, Paula F ^b   Costallat, Lilian T L ^b  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Amenorrhea; Cyclophosphamide; SLE

Indexed keywords

CORTICOSTEROID; CYCLOPHOSPHAMIDE; ESTRADIOL; FOLLITROPIN; IMMUNOSUPPRESSIVE AGENT; LUTEINIZING HORMONE; PROLACTIN;

ADOLESCENT; ADULT; AMENORRHEA; ARTICLE; CHI SQUARE TEST; DRUG DOSE REDUCTION; DRUG PULSE THERAPY; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MAJOR CLINICAL STUDY; ONSET AGE; OVARY INSUFFICIENCY; PRIORITY JOURNAL; RISK FACTOR; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT DURATION;

ADOLESCENT; ADULT; AMENORRHEA; CYCLOPHOSPHAMIDE; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; OVARIAN FAILURE, PREMATURE;

EID: 41049115751     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-007-0478-3     Document Type: Article

References (29)

1. Cervera R, Khamashtra MA, Font J et al (1993) Systemic lupus erythematosus: clinical and immunological patterns of disease expression in a cohort of 1,000 patients. Medicine 72:113-124
2. Balow JE, Austin HA, Tsokos GC, Antonovych TT, Steinberg AD, Klippel JH (1987) NIH conference: lupus nephritis. Ann Intern Med 106:79-94
3. Neuwelt CM, Lacks S, Kaye BR, Ellman JB, Borenstein DG (1995) Role of intravenous cyclophosphamide in the treatment of severe neuropsychiatric systemic lupus erythematosus. Am J Med 98:32-41
4. Boumpas DT, Austin III HA, Vaughn EM, Klippel JH, Steinberg AD, Yarboro CH, Balow JE (1992) Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis. Lancet 340:741-745
5. Boumpas DT, Barez S, Klippel JH, Balow JE (1990) Intermittent cyclophosphamide for the treatment of autoimmune thrombocytopenia in systemic lupus erythematosus. Ann Intern Med 112:674-677
6. Fukuda M, Kamiyama Y, Kawahara K, Kawamura K, Mori T, Honda M (1994) The favorable effect of cyclophosphamide pulse therapy in the treatment of massive pulmonary hemorrhage in systemic lupus erythematosus. J Pediatr 153:167-170
7. Schroeder JO, Euler HH, Loffler H (1987) Synchronization of plasmapheresis and pulse cyclophosphamide in severe systemic lupus erythematosus. Ann Intern Med 107:344-346
8. Valeri A, Radhakrishnan J, Estes D, D'Agati V, Kopelman R, Pernis A, Flis R, Pirani C, Appel GB (1994) Intravenous pulse cyclophosphamide treatment of severe lupus nephritis: a prospective five-year study. Clin Nephrol 42:71-78
9. Austin III HÁ, Klippel JH, Balow JE, Le Riche NGH, Steinberg AD, Plotz PH, Decker JL (1986) Therapy of lupus nephritis - controlled trial of prednisone and cytotoxic drugs. N Engl J Med 314:614-619
10. Houssiau FA, D'Cruz DP, Haga HJ, Hughes GRV (1991) Short course of weekly low-dose intravenous pulse cyclophosphamide in the treatment of lupus nephritis: a preliminary study. Lupus 1:31-35
11. Kumar R, Biggart JD, McEvoy J, McGeown MC (1972) Cyclophosphamide and reproductive function. Lancet 1:1212-1214
12. Martin F, Lauwerys B, Lefebvre C, Devogelaer JP, Houssiau FA (1997) Side-effects of intravenous cyclophosphamide pulse therapy. Lupus 6:254-257
13. Mok CC, Lau CS, Wong RWS (1998) Risk factors for ovarian failure in patients with systemic lupus erythematosus receiving cyclophosphamide therapy. Arthritis Rheum 41:831-837
14. McDermott EM, Powell RJ (1996) Incidence of ovarian failure in systemic lupus erythematosus after treatment with pulse cyclophosphamide. Ann Rheum Dis 55:224-229
15. Langevitz P, Klein L, Pras M, Many A (1992) The effect of cyclophosphamide pulses on fertility in patients with lupus nephritis. Am J Reprod Immunol 28:157-158
16. Huong DL, Amoura Z, Duhaut P, Sbai A, Costedoat N, Wechsler B, Piette JC (2002) Risk of ovarian failure and fertility after intravenous cyclophosphamide. A study in 84 patients. J Rheumatol 29:2571-2576
17. Warne GL, Fairley KF, Hobbs JB, Martin FIR (1973) Cyclophosphamide induced ovarian failure. N Engl J Med 289:1159-1162
18. Uldall PR, Kerr DNS, Tacchi D (1972) Sterility in cyclophosphamide. Lancet 1:693-694
19. Wang CL, Wang F, Bosco JJ (1995) Ovarian failure in oral cyclophosphamide treatment for systemic lupus erythematosus. Lupus 4:11-14
20. Boumpas DT, Austin HÁ, Vaughn EM, Yarboro CH, Klippel JH, Balow JE (1993) Risk for sustained amenorrhea in patients with systemic lupus erythematosus receiving intermittent pulse cyclophosphamide therapy. Ann Intern Med 119:366-369
21. Fogelman I (1996) The effects of oestrogen deficiency on the skeleton and its prevention. Br J Obstet Gynaecol 103(14):5-9
22. Van Der Schoun YT, Van der Graaf Y, Steyeberg EW, Eijkemans JC, Banga JD (1996) Age at menopause as a risk factor for cardiovascular mortality. Lancet 347:714-718
23. Tan EM, Cohen AJ, Fries JF (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271-1277
24. The Committee on Prognosis Studies in SLE, Bombardier C, Gladman DD, Urowitz M, Caron D, Chang C (1992) Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum 35:630-640
25. Gladman D, Glinzler E, Goldsmith C et al (1996) The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus. Arthritis Rheum 39:363-378
26. Brandt JT, Triplett DA, Scharer I (1995) Criteria for the diagnosis of lupus anticoagulant: an update. Thromb Haemost 74:1185-1190
27. Tincani A (2001) Cyclophosphamide therapy induces ovarian failure in premenopausal women affected by systemic lupus erythematosus. Clin Exp Rheumatol 19:490-491
28. Blumenfeld Z, Shapiro D, Shteinberg M, Avivi I, Nahir M (2000) Preservation of fertility and ovarian function and minimizing gonadotoxicity in young women with systemic lupus erythematosus treated by chemotherapy. Lupus 9:401-405
29. Pasoto SG, Mendonca BB, Bonfa E (2002) Menstrual disturbances in patients with systemic lupus erythematosus without alkylating therapy: clinical, hormonal and therapeutic associations. Lupus 11:175-180