Ontogeny of human intrahepatic innervation

Virchows Archiv

Volumn 452, Issue 4, 2008, Pages 435-442

  Tiniakos, Dina G ^a   Mathew, Joseph ^b   Kittas, Christos ^a   Burt, Alastair D ^c  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b ROYAL CORNWALL HOSPITAL   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Bile ducts; Development; Immunohistochemistry; Liver innervation; Peptidergic

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; GALANIN; NEUROPEPTIDE; SOMATOSTATIN;

ACINAR CELL; ADULT; ARTICLE; BILE DUCT; CONTROLLED STUDY; FETUS; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INNERVATION; LIVER; LIVER METABOLISM; MORPHOGENESIS; MOTOR PERFORMANCE; NERVE CELL NETWORK; ONTOGENY; PEPTIDERGIC NERVOUS SYSTEM; PORTAL VEIN; PRIORITY JOURNAL; SENSORY SYSTEM;

CALCITONIN GENE-RELATED PEPTIDE; FETAL DEVELOPMENT; FETUS; GALANIN; HUMANS; LIVER; NERVE FIBERS; SOMATOSTATIN;

EID: 41049089440     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-007-0569-2     Document Type: Article

References (36)

1. Akiyoshi H, Gonda T, Terada TA (1998) Comparative histochemical and immunohistochemical study of aminergic, cholinergic and peptidergic innervation in rat, hamster, guinea pig and human livers. Liver 18:352-359
2. Berthoud HR (2004) Anatomy and function of sensory hepatic nerves. Anat Rec 280A:827-835
3. Bioulac-Sage P, Lafon ME, Saric J, Balabaud C (1990) Nerves and perisinusoidal cells in human liver. J Hepatol 10:105-112
4. Burt AD, Tiniakos D, MacSween RNM, Griffiths MR, Wisse E, Polak JM (1989) Localization of adrenergic and neuropeptide tyrosine-containing nerves in the mammalian liver. Hepatology 9:839-845
5. Cassiman D, Denef C, Desmet VJ, Roskams T (2001) Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors. Hepatology 33:148-158
6. Cassiman D, Libbrecht L, Sinelli N, Desmet V, Denef C, Roskams T (2002) The vagal nerve stimulates activation of the hepatic progenitor cell compartment via muscarinic acetylcholine receptor 3. Am J Pathol 161:521-530
7. Cassiman D, Sinelli N, Bockx I, Vander Borght S, Petersen B, De Vos R, van Pelt J, Nevens F, Libbrecht L, Roskams T (2007) Human hepatic progenitor cells express vasoactive intestinal peptide receptor type 2 and receive nerve endings. Liver Int 27:323-328
8. Delalande JM, Milla PJ, Burns AJ (2004) Hepatic nervous system development. Anat Rec 280A:848-853
9. Ding WG, Kitasato H, Kimura H (1997) Development of neuropeptide Y innervation in the liver. Microsc Res Tech 15:365-371
10. El-Salhy M, Grimelius L, Emson PC, Falkmer S (1987) Polypeptide YY- and neuropeptide Y-immunoreactve cells and nerves in the endocrine and exocrine pancreas of some vertebrates: and onto- and phylogenetic study. Histochem J 19:111-117
11. El-Salhy M, Stenling R, Grimelius L (1983) Peptidergic innervation and endocrine cells in human liver. Scand J Gastroenterol 28:809-815
12. Feher E, Fodor M, Gorcs T, Feher J, Vallent K (1991) Immunohistochemical distribution of neuropeptide Y and catecholamine synthesizing enzymes in nerve fibers of the human liver. Digestion 50:194-201
13. Feher E, Fodor M, Feher J (1992) Ultrastructural localisation of somatostatin- and substance P immunoreactive nerve fibers in the feline liver. Gastroenterology 102:287-294
14. Goehler LE, Sternini C, Brecha NC (1988) Calcitonin gene-related peptide immunoreactivity in the biliary pathway and liver of the guinea pig: distribution and co-localization with substance P. Cell Tissue Res 253:145-150
15. Goehler LE, Sternini C (1991) Neuropeptide Y immunoreactivity in the mammalian liver: pattern of innervation and coexistence with tyrosine hydroxylase immunoreactivity. Cell Tissue Res 265:287-295
16. Jungermann K, Stumpel F (1999) Role of hepatic, intrahepatic and hepatoenteral nerves in the regulation of carbohydrate metabolism and hemodynamics of the liver and intestine. Hepatogastroenterol 46(suppl 2):1414-1417
17. Lafon ME, Bioulac-Sage P, LeBail B (1991) Nerves and perisinusoidal cells in human liver. In: Wisse E, Knook DL, McCuskey RS (eds) Cells of the hepatic sinusoid. Kupffer Cell Foundation, Rijswick, pp 230-234
18. Lee JA, Ahmed Q, Hines JE, Burt AD (1992) Disappearance of hepatic parenchymal nerves in human liver cirrhosis. Gut 33:87-91
19. Lin YS, Nosaka S, Amakata Y, Maeda T (1995) Comparative study of the mammalian liver innervation: an immunohistochemical study of PGP 9.5, dopamine-beta-hydroxylase and tyrosine hydroxylase. Comp Biochem Physiol A Physiol 110:289-298
20. McCuskey RS (2004) Anatomy of efferent hepatic nerves. Anat Rec 280A:821-826
21. Μiyazawa Y, Fukuda Y, Imoto M, Koyama Y, Nagura H (1988) Immunohistochemical studies on the distribution of nerve fibers in chronic liver diseases. Am J Gastroenterol 83:1108-1114
22. Nakatani K, Seki S, Kawada N, Kobayashi K, Kaneda K (1996) Expression of neural cell adhesion molecule (N-CAM) in perisinusoidal stellate cells of human liver. Cell Tissue Res 283:159-165
23. Oben JA, Roskams T, Yang S, Lin H, Sinelli N, Li Z, Torbenson M, Huang J, Guarino P, Kafrouni M, Diehl AM (2003) Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury. Hepatology 38:664-673
24. Oben JA, Diehl AM (2004) Sympathetic nervous system regulation of liver repair. Anat Rec 280A:874-883
25. Oben JA, Roskams T, Sinelli N, Li Z, Torbenson M, Yang S, Lin H, Smedh U, Moran TH, Thomas SH, Diehl AM (2004) Hepatic fibrogenesis requires sympathetic neurotransmitters. Gut 53:438-445
26. Püschel GP (2004) Control of hepatocyte metabolism by sympathetic and parasympathetic hepatic nerves. Anat Rec 280A:854-867
27. Roskams T, Cassiman D, De Vos R, Libbrecht L (2004) Neuroregulation of the neuroendocrine compartment of the liver. Anat Rec 280A:910-923
28. Saxena R, Theise N (2004) Canals of Hering: recent insights and current knowledge. Semin Liver Dis 24:43-48
29. Scoazec JY, Racine L, Couvelard A, Moreau A, Flejou JF, Bernuau D, Feldmann G (1993) Parenchymal innervation of normal and cirrhotic human liver: a light and electron microscopic study using monoclonal antibodies against neural cell-adhesion molecule. J Histochem Cytochem 41:899-908
30. Terada T, Nakanuma Y (1989) Innervation of intrahepatic bile ducts and peribiliary glands in normal human livers, extrahepatic biliary obstruction and hepatolithiasis: an immunohistochemical study. Hepatology 9:141-148
31. Tiniakos D, Tiniakos G, Burt AD (1994) Peptidergic innervation of human fetal liver (abstract). J Hepatol 21(suppl 1):S73
32. Tiniakos D, Anagnostou V, Stavrakis S, Karandrea D, Agapitos A, Kittas C (2004) Ontogeny of intrinsic innervation in the human kidney. Anat Embryol 209:41-47
33. Ueno T, Inuzuka S, Torimura T, Sakata R, Sakamoto R, Gondo K, Aoki T, Tanikawa K, Tsutsumi V (1991) Distribution of substance P and VIP in the human liver. Am J Gastroenterol 86:1633-1637
34. Ueno T, Tanikawa K (1996) Intralobular innervation and lipocyte contractility in the liver. Nutrition 13:141-148
35. Ueno T, Bioulac-Sage P, Balabaud C, Rosenbaum J (2004) Innervation of the sinusoidal wall: regulation of the sinusoidal diameter. Anat Rec 280A:868-873
36. Zanchi A, Feldman H, Reidy J, Qualter J, Theise N (2005) Innervation of a intraorgan hepatic progenitor cell "niche" in normal human liver (abstract). Hepatology 42(suppl 1):279A