The prostate cancer prevention trial and the future of chemoprevention

BJU International

Volumn 101, Issue 8, 2008, Pages 933-934

  Thompson, Ian M ^a,b   Tangen, Catherine M ^c   Lucia, M Scott ^d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio

^c Fred Hutchinson Cancer Research Center   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DUTASTERIDE; FINASTERIDE; PLACEBO; PROSTATE SPECIFIC ANTIGEN; TUMOR MARKER;

CANCER DIAGNOSIS; CANCER PREVENTION; CANCER RISK; CHEMOPROPHYLAXIS; CLINICAL TRIAL; DIAGNOSTIC VALUE; DISEASE MARKER; DRUG APPROVAL; DRUG EFFECT; DRUG POTENCY; FOOD AND DRUG ADMINISTRATION; HUMAN; NOTE; PRIORITY JOURNAL; PROSTATE BIOPSY; PROSTATE CANCER; PROSTATIC INTRAEPITHELIAL NEOPLASIA; RISK REDUCTION;

ANTINEOPLASTIC AGENTS; CHEMOPREVENTION; ENZYME INHIBITORS; FINASTERIDE; HUMANS; MALE; PROSTATIC NEOPLASMS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 40949166235     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2008.07482.x     Document Type: Note

References (9)

1. Thompson IM, Goodman PJ, Tangen CM et al. The influence of finasteride on the development of prostate cancer. N Engl J Med 2003 349 : 215 24
2. Scardino PT. The prevention of prostate cancer - the dilemma continues. N Engl J Med 2003 349 : 297 9
3. Thompson IM, Chi C, Ankerst DP et al. Effect of finasteride on the sensitivity of PSA for detecting prostate cancer. J Natl Cancer Inst 2006 98 : 1128 33
4. Thompson IM, Tangen CM, Goodman PJ et al. Finasteride improves the sensitivity of digital rectal examination for prostate cancer detection. J Urol 2007 177 : 1749 52
5. Lucia MS, Epstein JI, Goodman PJ et al. Finasteride and high-grade prostate cancer in the Prostate Cancer Prevention Trial. J Natl Cancer Inst 2007 99 : 1375 83
6. Shepherd B, Redman MW, Ankerst DP. Does finasteride affect the severity of prostate cancer? A causal sensitivity analysis. J Am Stat Assoc 2008 (in press)
7. Thompson IM, Lucia MS, Redman MW et al. Finasteride decreases the risk of prostatic intraepithelial neoplasia. J Urol 2007 178 : 107 9
8. Moinpour CM, Darke AK, Donaldson GW et al. Longitudinal analysis of sexual function reported by men in the Prostate Cancer Prevention Trial. J Natl Cancer Inst 2007 99 : 1025 35
9. Andriole G, Bostwick D, Brawley O et al. Chemoprevention of prostate cancer in men at high risk: rationale and design of the reduction by dutasteride of prostate cancer events (REDUCE) trial. J Urol 2004 172 : 1314 7