Distribution of glycine immunoreactivity in the brain of adult sea lamprey (Petromyzon marinus). Comparison with γ-aminobutyric acid

Journal of Comparative Neurology

Volumn 507, Issue 3, 2008, Pages 1441-1463

  Villar Cerviño, Verona ^a   Barreiro Iglesias, Antón ^a   Anadón, Ramón ^a   Rodicio, María Celina ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Agnathans; Colocalization; Confocal microscopy; GABA; Glycinergic; Immunocytochemistry

Indexed keywords

4 AMINOBUTYRIC ACID; GLYCINE;

ABDUCENS NUCLEUS; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN STEM; CELL POPULATION; COMPARATIVE STUDY; CONTROLLED STUDY; EVOLUTION; FOREBRAIN; GABAERGIC SYSTEM; IMMUNOREACTIVITY; MESENCEPHALON; MOTONEURON NUCLEUS; NONHUMAN; OLFACTORY BULB; PETROMYZON; PHYLOGENY; PRIORITY JOURNAL; RHOMBENCEPHALON; SPINE; TEGMENTUM;

AGE FACTORS; ANIMALS; ANTIBODIES; BRAIN; CEREBRAL CORTEX; CORPUS STRIATUM; EVOLUTION; GAMMA-AMINOBUTYRIC ACID; GLYCINE; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; LAMPREYS; MICROSCOPY, CONFOCAL; OLFACTORY BULB; PREOPTIC AREA; RETICULAR FORMATION; SUPERIOR COLLICULI; THALAMUS;

EID: 40949160166     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.21634     Document Type: Article

References (117)

1. Abalo XM, Villar-Cheda B, Meléndez-Ferro M, Pérez-Costas E, Anadón R, Rodicio MC. 2007. Development of the serotonergic system in the central nervous system of the sea lamprey. J Chem Neuroanat 34:29-46.
2. Alford S, Williams TL. 1989. Endogenous activation of glycine and NMDA receptors in lamprey spinal cord during fictive locomotion. J Neurosci 9:2792-2800.
3. Alford S, Sigvardt KA, Williams TL. 1990a. GABAergic control of rhythmic activity in the presence of strychnine in the lamprey spinal cord. Brain Res 506:303-306.
4. Alford S, Williams TL, Sigvardt KA. 1990b. Effects of bicuculline and strychnine on synaptic inputs to edge cells during fictive locomotion. Brain Res 509:137-140.
5. Álvarez-Otero R, Pérez SE, Rodríguez MA, Anadón R. 1996. Organization of the cerebellar nucleus of the dogfish, Scyliorhinus canicula L.: a light microscopic, immunocytochemical and ultrastructural study. J Comp Neurol 368:487-502.
6. Antri M, Cyr A, Auclair F, Dubuc R. 2006. Ontogeny of 5-HT neurons in the brainstem of the lamprey, Petromyzon marinus. J Comp Neurol 495:788-800.
7. Aoki E, Semba R, Keino H, Kato K, Kashiwamata S. 1988. Glycine-like immunoreactivity in the rat auditory pathway. Brain Res 442:63-71.
8. Baev KV, Rusin KI, Safronov BV. 1992. Primary receptor for inhibitory transmitters in lamprey spinal cord neurons. Neuroscience 46:931-941.
9. Barker JL, Ransom BR. 1978. Amino acid pharmacology of mammalian central neurones grown in tissue culture. J Physiol 280:331-354.
10. Bäurle J, Grüsser-Cornehls U. 1997. Differential number of glycine- and GABA-immunopositive neurons and terminals in the deep cerebellar nuclei of normal and Purkinje cell degeneration mutant mice. J Comp Neurol 382:443-458.
11. Betz H. 1987. Biology and structure of the mammalian glycine receptor. Trends Neurosci 10:113-117.
12. Birinyi A, Parker D, Antal M, Shupliakov O. 2001. Zinc co-localizes with GABA and glycine in synapses in the lamprey spinal cord. J Comp Neurol 433:208-221.
13. Bongianni F, Mutolo D, Nardone F, Pantaleo T, 2006. GABAergic and glycinergic inhibitory mechanisms in the lamprey respiratory control. Brain Res 1090:134-145.
14. Bormann J, Hamill OP, Sakmann B. 1987. Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones. J Physiol 385:243-286.
15. Brodin L, Grillner S, Rovainen CM. 1985. N-methyl-D-aspartate (NMDA), kainate and quisqualate receptors and the generation of fictive locomotion in the lamprey spinal cord. Brain Res 325:302-306.
16. 3H)D-aspartate. J Comp Neurol 281:225-233.
17. Buchanan JT, Grillner S. 1988. A new class of small inhibitory interneurones in the lamprey spinal cord. Brain Res 438:404-407.
18. Bullock TH, Moore JK, Fields RD. 1984. Evolution of myelin sheaths: both lamprey and hagfish lack myelin. Neurosci Lett 48:145-148.
19. Campistron G, Buijs RM, Geffard M. 1986. Glycine neurons in the brain and spinal cord. Antibody production and immunocytochemical localization. Brain Res 376:400-405.
20. Cubelos B, Giménez C, Zafra F. 2005. Localization of the glycineT1 glycine transporter at glutamatergic synapses in the rat brain. Cereb Cortex 15:448-459.
21. Dale N, Ottersen OP, Roberts A, Storm-Mathisen J. 1986. Inhibitory neurones of a motor pattern generator in Xenopus revealed by antibodies to glycine. Nature 324:255-257.
22. David-Watine B, Goblet C, de Saint Jan D, Fucile S, Devignot V, Bregestovski P, Korn H. 1999. Cloning, expression and electrophysiological characterization of glycine receptor alpha subunit from zebrafish. Neuroscience 90:303-317.
23. De Arriba Pérez MC. 2007. Conexiones del techo optico. Organization y desarrollo en lamprea y expresión de genes implicados en la vía retinotectal en pez cebra. PhD Dissertation, University of Vigo.
24. De Arriba MC, Pombal MA. 2007. Afferent connections of the optic tectum in lampreys: an experimental study. Brain Behav Evol 69:37-68.
25. Dubuc R, Bongianni F, Ohta Y, Grillner S. 1993a. Dorsal root and dorsal column mediated synaptic inputs to reticulospinal neurons in lampreys: involvement of glutamatergic, glycinergic, and GABAergic transmission. J Comp Neurol 327:251-259.
26. Dubuc R, Bongianni F, Ohta Y, Grillner S. 1993b. Anatomical and physiological study of brainstem nuclei relaying dorsal column inputs in lampreys. J Comp Neurol 327:260-270.
27. Fort P, Luppi PH, Wenthold R, Jouvet M. 1990. Glycine immunoreactive neurons in the medulla oblongata in cats. C R Acad Sci 311:205-212.
28. Fort P, Luppi PH, Jouvet M. 1993. Glycine-immunoreactive neurones in the cat brain stem reticular formation. Neuroreport 4:1123-1126.
29. Fritzsch B, Sonntag R, Dubuc R, Ohta Y, Grillner S. 1990. Organization of the six motor nuclei innervating the ocular muscles in lamprey. J Comp Neurol 294:491-506.
30. Garrow TA, Brenner AA, Whitehead VM, Chen XN, Duncan RG, Korenberg JR, Shane B. 1993. Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization. J Biol Chem 268:11910-11916.
31. Gold MR, Martin AR. 1983. Inhibitory conductance changes at synapses in the lamprey brainstem. Science 221:85-87.
32. González MJ, Anadón R. 1992. Primary projections of the lateral line nerves in larval sea lamprey, Petromyzon marinus L. An HRP study. J Hirnforsch 33:185-194.
33. González MJ, Anadón R. 1994. Central projections of the octaval nerve in larval lamprey: an HRP study. J Hirnforsch 35:181-189.
34. González MJ, Manso MJ, Anadón R. 1997. Octavolateral neurons projecting to the middle and posterior rhombencephalic reticular nuclei of larval lamprey: a retrograde horseradish peroxidase labelling study. J Comp Neurol 384:396-408.
35. González MJ, Pombal MA, Rodicio MC, Anadón R. 1998. The internuclear neurons of the ocular motor system of the larval sea lamprey. J Comp Neurol 401:1-15.
36. González MJ, Yáñez J, Anadón R. 1999. Afferent and efferent connections of the torus semicircularis in the sea lamprey: an experimental study. Brain Res 826:83-94.
37. Gravel J, Brocard F, Gariépy JF, Lund JP, Dubuc R. 2007. Modulation of respiratory activity by locomotion in lampreys. Neuroscience 144:1120-1132.
38. Grillner S, Wallén P. 2002. Cellular bases of a vertebrate locomotor system-steering, intersegmental and segmental co-ordination and sensory control. Brain Res Rev 40:92-106.
39. Guimond JC, Auclair F, Lund JP, Dubuc R. 2003. Anatomical and physiological study of respiratory motor innervation in lampreys. Neuroscience 122:259-266.
40. Hardisty MW, Rovainen CM. 1982. Morphological and functional aspects of the muscular system. In: Hardisty MW, Potter IC, editors. The biology of lampreys, vol 4. London: Academic Press. p 137-231.
41. Helfert RH, Bonneau JM, Wenthold RJ, Altschuler RA. 1989. GABA and glycine immunoreactivity in the guinea pig superior olivary complex. Brain Res 501:269-286.
42. Higashijima S, Mandel G, Fetcho JR. 2004. Distribution of prospective glutamatergic, glycinergic, and GABAergic neurons in embryonic and larval zebrafish. J Comp Neurol 480:1-18.
43. Hökfelt T, Ljungdahl A. 1971. Light and electron microscopic autoradiography on spinal cord slices after incubation with labeled glycine. Brain Res 32:189-194.
44. Homma S. 1978. Organization of the trigeminal motor nucleus before and after metamorphosis in lampreys. Brain Res 140:33-42.
45. Homma S, Rovainen CM. 1978. Conductance increases produced by glycine and gamma-aminobutyric acid in lamprey interneurones. J Physiol 279:231-252.
46. Huard H, Lund JP, Veilleux D, Dubuc R. 1999. An anatomical study of brainstem projections to the trigeminal motor nucleus of lampreys. Neuroscience 91:363-378.
47. Imboden M, De Saint Jan D, Leulier F, Korn H, Goblet C, Bregestovski P. 2001. Isolation and characterization of an alpha 2-type zebrafish glycine receptor subunit. Neuroscience 103:799-810.
48. 3H-glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography. Brain Res 41:131-143.
49. Kolston J, Osen KK, Hackney CM, Ottersen OP, Storm-Mathisen J. 1992. An atlas of glycine- and GABA-like immunoreactivity and colocalization in the cochlear nuclear complex of the guinea pig. Anat Embryol 186:443-465.
50. Koyama H. 2005. Organization of the sensory and motor nuclei of the glossopharyngeal and vagal nerves in lampreys. Zool Sci 22:469-476.
51. Koyama H, Kishida R, Goris RC, Kusunoki T. 1987. Organization of sensory and motor nuclei of the trigeminal nerve in lampreys. J Comp Neurol 264:437-448.
52. Koyama H, Kishida R, Goris RC, Kusunoki T. 1989. Afferent and efferent projections of the VIIIth cranial nerve in the lamprey Lampetra japonica. J Comp Neurol 280:663-671.
53. Landwehr S, Dicke U. 2005. Distribution of GABA, glycine, and glutamate in neurons of the medulla oblongata and their projections to the midbrain tectum in plethodontid salamanders. J Comp Neurol 490:145-162.
54. Lannoo MJ, Hawkes R. 1997. A search for primitive Purkinje cells: zebrin II expression in sea lampreys (Petromyzon marinus). Neurosci Lett 237:53-55.
55. 3H-glycine in interneurons of the cat spinal cord. Histochemie 33:277-280.
56. Lue JH, Shieh WF, Chen SH, Shieh JY, Wen CY. 1997. Morphometry study of glycine-immunoreactive neurons and terminals in the rat cuneate nucleus. J. Anat 191:375-385.
57. Matthews G, Wickelgren WO. 1979. Glycine, GABA and synaptic inhibition of reticulospinal neurones of lamprey. J Physiol 293:393-415.
58. McClellan AD, Zhang L, Palmer R. 2006. Fluorogold labeling of descending brain neurons in larval lamprey does not cause cell death. Neurosci Lett 401:119-124.
59. McPherson DR, Buchanan JT, Kasicki S. 1994. Effects of strychnine on fictive swimming in the lamprey: evidence for glycinergic inhibition, discrepancies with model predictions, and novel modulatory rhythms. J Comp Physiol A175:311-321.
60. Meléndez-Ferro M. 2001. Distribución de la inmunorreactividad al ácido gamma-aminobutírico (GABA) en el sistema nervioso central de la lamprea de mar durante el desarrollo y la etapa adulta. PhD Dissertation, University of Santiago de Compostela.
61. Meléndez-Ferro M, Pérez-Costas E, Rodríguez- Muñoz R, Gómez-López MP, Anadón R, Rodicio MC. 2001. GABA immunoreactivity in the olfactory bulbs of the adult sea lamprey Petromyzon marinus L. Brain Res 893:253-260.
62. Meléndez-Ferro M, Pérez-Costas E, Villar-Cheda B, Abalo XM, Rodríguez-Muñoz R, Rodicio MC, Anadón R. 2002. Ontogeny of γ-aminobutyric acid-immunoreactive neuronal populations in the forebrain and midbrain of the sea lamprey. J Comp Neurol 446:360-376.
63. Meléndez-Ferro M, Pérez-Costas E, Villar-Cheda B, Rodriγguez-Muñoz R, Anadón R, Rodicio MC. 2003. Ontogeny of γ-aminobutyric acid-immunoreactive neurons in the rhombencephalon and spinal cord of the sea lamprey. J Comp Neurol 464:17-35.
64. Ménard A, Auclair F, Bourcier-Lucas C, Grillner S, Dubuc R. 2007. Descending GABAergic projections to the mesencephalic locomotor region in the lamprey Petromyzon marinus. J Comp Neurol 501:260-273.
65. Merchán M, Aguilar LA, Lopez-Poveda EA, Malmierca MS. 2005. The inferior colliculus of the rat: quantitative immunocytochemical study of GABA and glycine. Neuroscience 136:907-925.
66. Merrick SE, Pleasure SJ, Lurie DI, Pijak DS, Selzer ME, Lee VM. 1995. Glial cells of the lamprey nervous system contain keratin-like proteins. J Comp Neurol 355:199-210.
67. Mugnaini E, Oertel WH, Wouterlood FF. 1984. Immunocytochemical localization of GABA neurons and dopamine neurons in the rat main and accessory olfactory bulbs. Neurosci Lett. 47:221-226.
68. Murakami Y, Pasqualetti M, Takio Y, Hirano S, Rijli FM, Kuratani S. 2004. Segmental development of reticulospinal and branchiomotor neurons in lamprey: insights into the evolution of the vertebrate hindbrain. Development 131:983-995.
69. Nieuwenhuys R. 1972. Topological analysis of the brain stem of the lamprey Lampetra fluviatilis. J Comp Neurol 145:165-178.
70. Nieuwenhuys R, Nicholson C. 1998. Lampreys, Petromyzontoidea. In: Nieuwenhuys R, ten Donkelaar HJ, Nicholson C, editors. The central nervous system of vertebrates, vol 1. Berlin: Springer Verlag. p 397-486.
71. Northcutt RG. 1979. Central projections of the eighth cranial nerve in lampreys. Brain Res 167:163-167.
72. Northcutt RG, Puzdrowski RL. 1988. Projections of the olfactory bulb and nervus terminalis in the silver lamprey. Brain Behav Evol 32:96-107.
73. Northcutt RG, Wicht H. 1997. Afferent and efferent connections of the lateral and medial pallia of the silver lamprey. Brain Behav Evol 49:1-19.
74. Ohta Y, Grillner S. 1989. Monosynaptic excitatory amino acid transmission from the posterior rhombencephalic reticular nucleus to spinal neurons involved in the control of locomotion in lamprey. J Neurophysiol 62:1079-1089.
75. Pflieger JF, Dubuc R. 2004. Vestibulo-reticular projections in adult lamprey: their role in locomotion. Neuroscience 129:817-829.
76. Pombal MA, Puelles L. 1999. A prosomeric map of the lamprey forebrain based on calretinin immunocytochemistry, Nissl stain and ancillary markers. J Comp Neurol 414:391-422.
77. Pombal MA, El Manira A, Grillner S. 1997a. Afferents of the lamprey striatum with special reference to the dopaminergic system: a combined tracing and immunohistochemical study. J Comp Neurol 386:71-91.
78. Pombal MA, El Manira A, Grillner S. 1997b. Organization of the lamprey striatum - transmitters and projections. Brain Res 766:249-254.
79. Pombal MA, Marín O, González A. 2001. Distribution of choline acetyltransferase-immunoreactive structures in the lamprey brain. J Comp Neurol 431:105-126.
80. Pombal MA, López JM, de Arriba MC, Megías M, González A. 2006. Distribution of neuropeptide FF-like immunoreactive structures in the lamprey central nervous system and its relation to catecholaminergic neuronal structures. Peptides 27:1054-1072.
81. Pourcho RG, Goebel DJ, Jojich L, Hazlett JC. 1992. Immunocytochemical evidence for the involvement of glycine in sensory centers of the rat brain. Neuroscience 46:643-656.
82. Popratiloff A, Valtschanoff JG, Rustioni A, Weinberg RJ. 1996. Colocalization of GABA and glycine in the rat dorsal column nuclei. Brain Res. 706:308-312.
83. Rampon C, Luppi PH, Fort P, Peyron C, Jouvet M. 1996. Distribution of glycine-immunoreactive cell bodies and fibers in the rat brain. Neuroscience 75:737-755.
84. Reichenberger I, Streit P, Ottersen OP, Dieringer N. 1993. GABA- and glycine-like immunoreactivities in the cerebellum of the frog. Neurosci Lett 154:89-92.
85. Reichenberger I, Straka H, Ottersen OP, Streit P, Gerrits NM, Dieringer N. 1997. Distribution of GABA, glycine, and glutamate immunoreactivities in the vestibular nuclear complex of the frog. J Comp Neurol 377:149-164.
86. Robertson B, Saitoh K, Menard A, Grillner S. 2006. Afferents of the lamprey optic tectum with special reference to the GABA input: combined tracing and immunohistochemical study. J Comp Neurol 499:106-119.
87. Robertson B, Auclair F, Menard A, Grillner S, Dubuc R. 2007. GABA distribution in lamprey is phylogenetically conserved. J Comp Neurol 503:47-63.
88. Rodicio MC, Villar-Cervino V, Abalo XM, Villar-Cheda B, Meléndez-Ferro M, Pérez-Costas E, Anadón R. 2005. Chemoarchitecture of the dorsal column nucleus of the larval sea lamprey. Brain Res Bull 66:536-540.
89. Ronan M, Northcutt RG. 1987. Primary projections of the lateral line nerves in adult lampreys. Brain Behav Evol 30:62-81.
90. Rovainen CM. 1983. Generation of respiratory activity by the lamprey brain exposed to picrotoxin and strychnine, and weak synaptic inhibition in motoneurons. Neuroscience 10:875-882.
91. Saint Marie RL, Ostapoff EM, Morest DK, Wenthold RJ. 1989. Glycine-immunoreactive projection of the cat lateral superior olive: possible role in midbrain ear dominance. J Comp Neurol 279:382-396.
92. Saint Marie RL, Benson CG, Ostapoff EM, Morest DK 1991. Glycine immunoreactive projections from the dorsal to the anteroventral cochlear nucleus. Hear Res 51:11-28.
93. Schober W. 1964. Vergleichend-anatomische Untersuchungen am Gehirn der Larven und adulten Tiere von Lampetra fluviatilis (Linné, 1758) und Lampetra planeri (Bloch, 1784). J Hirnforsch 7:107-209.
94. Sheridan PH, Youngs LJ, Krieger NR, Selzer ME. 1984. Glycine uptake by lamprey spinal neurons demonstrated by light microscopic autoradiography. J Comp Neurol 223:252-258.
95. Shupliakov O, Fagersted P, Ottersen OP, Storm-Mathiesen J, Grillner S, Brodin L. 1996. Immunocytochemical localization of glycine in the lamprey spinal cord with reference to GABAergic and glutamatergic synapses: a light and electron microscopic study. Acta Biol Hung 47:393-410.
96. Spirou GA, Berrebi AS. 1997. Glycine immunoreactivity in the lateral nucleus of the trapezoid body of the cat. J Comp Neurol 383:473-488.
97. Stefanelli A. 1934. I centri tegmentali dell'encefalo dei Petromizonti. Arch Zool Ital 20:117-202.
98. Stefanelli A. 1937. Il sistema statico dei Petromizonti (sistema laterale, sistema vestibolare, cervelletto). I: centri nervosi e vie centrali. Arch Zool Ital 24:209-273.
99. Stefanelli A, Caravita S. 1970. Ultrastructural features of the synaptic complex of the vestibular nuclei of Lampetra planeri (Bloch). Z Zellforsch 108:282-296.
100. Shupliakov O, Fagersted P, Ottersen OP, Storm-Mathiesen J, Grillner S, Brodin L. 1996. Immunocytochemical localization of glycine in the lamprey spinal cord with reference to GABAergic and glutamatergic synapses: a light and electron microscopic study. Acta Biol Hung 47:393-410.
101. Tanaka I, Ezure K. 2004. Overall distribution of GLYT2 mRNA-containing versus GAD67 mRNA-containing neurons and colocalization of both mRNAs in midbrain, pons, and cerebellum in rats. Neurosci Res 49:165-178.
102. Uematsu K, Shirasaki M, Storm-Mathisen J. 1993. GABA- and glycine-immunoreactive neurons in the spinal cord of the carp, Cyprinus carpio. J Comp Neurol 332:59-68.
103. Vesselkin NP, Rio JP, Adanina VO, Kenigfest NB, Repérant J. 1995. Colocalization of glutamate and glycine in giant fiber synapses of the lamprey spinal cord. J Hirnforsch 36:229-237.
104. Vesselkin NP, Rio JP, Adanina VO, Repérant J. 2000. GABA- and glycine-immunoreactive terminals contacting motoneurons in lamprey spinal cord. J Chem Neuroanat 19:69-80.
105. Viana Di Prisco G, Ohta Y, Bongianni F, Grillner S, Dubuc R. 1995. Trigeminal inputs to reticulospinal neurones in lampreys are mediated by excitatory and inhibitory amino acids. Brain Res 695:76-80.
106. Viana Di Prisco G, Pearlstein E, Robitaille R, Dubuc R. 1997. Role of sensory-evoked NMDA plateau potentials in the initiation of locomotion. Science 278:1122-1125.
107. Viana Di Prisco G, Boutin T, Petropoulos D, Brocard F, Dubuc R. 2005. The trigeminal sensory relay to reticulospinal neurones in lampreys. Neuroscience 131:535-546.
108. Villar-Cerviño V, Abalo XM, Villar-Cheda B, Meléndez-Ferro M, Pérez-Costas E, Holstein GR, Martinelli GP, Rodicio MC, Anadón R. 2006. Presence of glutamate, glycine, and gamma-aminobutyric acid in the retina of the larval sea lamprey: comparative immunohistochemical study of classical neurotransmitters in larval and postmetamorphic retinas. J Comp Neurol 499:810-827.
109. Villar-Cerviño V, Holstein GR, Martinelli GP, Anadón R, Rodicio MC. 2008. Glycine-immunoreactive neurons in the developing spinal cord of the sea lamprey. A comparison with the GABAergic system. J Comp Neurol (in press).
110. Walberg F, Ottersen OP, Rinvik E. 1990. GABA, glycine, aspartate, glutamate and taurine in the vestibular nuclei: an immunocytochemical investigation in the cat. Exp Brain Res 79:547-563.
111. Wannier T, Orlovsky G, Grillner S. 1995. Reticulospinal neurones provide monosynaptic glycinergic inhibition of spinal neurones in lamprey. Neuroreport 6:1597-1600.
112. Wenthold RJ. 1987. Evidence for a glycinergic pathway connecting the two cochlear nuclei: an immunocytochemical and retrograde transport study. Brain Res 415:183-187.
113. Wood PL. 2005. The NMDA receptor complex: a long and winding road to therapeutics. IDrugs 8:229-235.
114. Yáñez J, Pombal MA, Anadón R. 1999. Afferent and efferent connections of the parapineal organ in lamprey: a tract tracing and immunocytochemical study. J Comp Neurol 403:171-189.
115. Young AB, Snyder SH. 1974. The glycine synaptic receptor: evidence that strychnine binding is associated with the ionic conductance mechanism. Proc Natl Acad Sci U S A 71:4002-4005.
116. Zeilhofer HU, Studler B, Arabadzisz D, Schweizer C, Ahmadi S, Layh B, Bosl MR, Fritschy JM. 2005. Glycinergic neurons expressing enhanced green fluorescent protein in bacterial artificial chromosome transgenic mice. J Comp Neurol 482:123-141.
117. Zompa IC, Dubuc R. 1998. Diencephalic and mesencephalic projections to rhombencephalic reticular nuclei in lampreys. Brain Res 802:27-54.