Membrane interaction and structure of the transmembrane domain of influenza hemagglutinin and its fusion peptide complex

BMC Biology

Volumn 6, Issue , 2008, Pages

  Chang, Ding Kwo ^a   Cheng, Shu Fang ^a   Kantchev, Eric Aseen B ^b   Lin, Chi Hui ^a   Liu, Yu Tsan ^a  

^a INSTITUTE OF CHEMISTRY   (Taiwan)

^b INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; HYBRID PROTEIN; INFLUENZA VIRUS HEMAGGLUTININ; OLIGOMER; PEPTIDE; VIRUS GLYCOPROTEIN; RHODAMINE; VIRUS FUSION PROTEIN;

ARTICLE; ARTIFICIAL MEMBRANE; CELL TRANSPORT; CHANNEL GATING; COMPLEX FORMATION; DRUG DESIGN; FLUORESCENCE; GEL ELECTROPHORESIS; INFLUENZA VIRUS; MEMBRANE FUSION; MEMBRANE STRUCTURE; MOLECULAR INTERACTION; PROTEIN DOMAIN; VIRUS ENVELOPE; CHEMISTRY; GENETICS; LIPID BILAYER; PROTEIN SECONDARY STRUCTURE; SPECTROFLUOROMETRY;

ORTHOMYXOVIRIDAE;

HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; LIPID BILAYERS; MEMBRANE FUSION; PROTEIN STRUCTURE, SECONDARY; RHODAMINES; SPECTROMETRY, FLUORESCENCE; VIRAL FUSION PROTEINS;

EID: 40949146126     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-6-2     Document Type: Article

References (36)

1. Chang DK Cheng SF Chien WJ The amino-terminal fusion domain peptide of HIV-1 gp41 inserts into the sodium dodecyl sulfate micelle primarily as a helix with a conserved glycine at the micelle-water interface J Virol 1997, 71:6593-6602. 191937 9261381
2. Carr CM Chaudhry C Kim PS Influenza hemagglutinin is spring-loaded by a metastable native conformation Proc Natl Acad Sci USA 1997, 94:14306-14313. 24954 9405608 10.1073/pnas.94.26.14306
3. Ishiguro R Kimura N Takahashi S Orientation of fusion-active synthetic peptides in phospholipid bilayers: Determination by Fourier transform infrared spectroscopy Biochemistry 1993, 32:9792-9797. 10.1021/ bi00088a034 8373779
4. Gruenke JA Armstrong RT Newcomb WW Brwon JC White JW New insights into the spring-loaded conformational change of influenza virus hemagglutinin J Virol 2002, 6:74456-4466.
5. Lai AL Park H White JM Tamm LK Fusion peptide of influenza hemagglutinin requires a fixed angle boomerang structure for activity J Biol Chem 2006, 281:5760-5770. 10.1074/jbc.M512280200 16407195
6. Kemble GW Danieli T White JM Lipidanchored influenza hemagglutinin promotes hemifusion, not complete fusion Cell 1994, 76:383-391. 10.1016/ 0092-8674(94)90344-1 8293471
7. Armstrong RT Kushnir AS White JM The transmembrane domain of influenza hemagglutinin exhibits a stringent length requirement to support the hemifusion to fusion transition J Cell Biol 2000, 151:425-437. 10.1083/ jcb.151.2.425 11038188
8. Miyauchi K Komano J Yokomaku Y Sugiura W Yamamoto N Matsuda Z Role of the specific amino acid sequence of the membrane-spanning domain of human immunodeficiency virus type 1 in membrane fusion J Virol 2005, 79:4720-4729. 1069530 15795258 10.1128/JVI.79.8.4720-4729.2005
9. Owens RJ Burk C Rose JK Mutations in the membrane-spanning domain of the human immunodeficiency virus envelope glycoprotein that affect fusion activity J Virol 1994, 68:570-574. 236324 8254774
10. Tatulian SA Tamm LK Secondary structure, orientation, oligomerization, and lipid interactions of the transmembrane domain of influenza hemagglutinin Biochemistry 2000, 39:496-506. 10.1021/bi991594p 10642174
11. Melikyan GB Lin SS Roth MG Cohen FS Amino acid sequence requirements of the transmembrane and cytoplasmic domains of influenza virus hemagglutinin for viable membrane fusion Mol Biol Cell 1999, 10:1821-1836. 25377 10359599
12. Tamm LK Hypothesis: Spring-loaded boomerang mechanism of influenzahemagglutinin-mediated membrane fusion Biochim Biophys Acta 2003, 1614:14-23. 10.1016/S0005-2736(03)00159-7 12873762
13. Ungar D Hughson FM SNARE protein structure and function Annu Rev Cell Dev Biol 2003, 19:493-517. 10.1146/annurev.cellbio.19.110701.155609 14570579
14. Han X Wang CT Bai J Chapman ER Jackson MB Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis Science 2004, 304:289-292. 10.1126/science.1095801 15016962
15. White JM Castle JD Searching for the silver lining Nat Struct Mol Biol 2005, 12:382-384. 10.1038/nsmb0505-382 15870723
16. Cheng SF Kantchev AB Chang DK Fluorescence evidence for a loose self-assembly of the fusion peptide of influenza virus HA2 in the lipid bilayer Mol Membr Biol 2003, 20:345-351. 10.1080/0968708031000138046 14578049
17. Kliger Y Aharoni A Rapaport D Jones P Blumenthalo R Shai Y Fusion peptides derived from the HIV type 1 glycoprotein 41 associate within phospholipid membranes and inhibit cell-cell fusion J Biol Chem 1997, 272:13496-13505. 10.1074/jbc.272.21.13496 9153194
18. Chang DK Cheng SF Lin CH Kantchev EAB Wu CW Self-association of glutamic acid-rich fusion peptide analogs of influenza hemagglutinin in the membrane-mimic environments: Effects of positional difference of glutamic acids on side chain ionization constant and intra- and inter-peptide interactions deduced from NMR and gel electrophoresis measurements Biochim Biophys Acta 2005, 1712:37-51. 10.1016/ j.bbamem.2005.04.003 15896704
19. Chang DK Cheng SF pH-dependence of intermediate steps of membrane fusion induced by the influenza fusion peptide Biochem J 2006, 396:557-563. 1482821 16519629 10.1042/BJ20051920
20. Chang DK Cheng SF Trivedi VD Biophysical characterization of the structure of the amino-terminal region of gp41 of HIV-1 - Implications on viral fusion mechanism J Biol Chem 1999, 274:5299-5309. 10.1074/ jbc.274.9.5299 10026137
21. Sanchez-Martinez S Lorizate M Katinger H Kunert R Nieva JL Membrane association and epitope recognition by HIV-1 neutralizing anti-gp41 2F5 and 4E10 antibodies AIDS Res Hum Retroviruses 2006, 22:998-1006. 10.1089/ aid.2006.22.998 17067270
22. Moreno MR Pascual R Villalain J Identification of membrane-active regions of the HIV-1 envelope glycoprotein gp41 using a 15-mer gp41-peptide scan Biochim Biophys Acta 2004, 1661:97-105. 10.1016/ j.bbamem.2003.12.003 14967479
23. Cohen CS Melikyan GB The energetics of membrane fusion from binding, through hemifusion, pore formation, and pore enlargement J Membr Biol 2004, 199:1-14. 10.1007/s00232-004-0669-8 15366419
24. Helseth E Olshevsky U Gabuzda D Ardman B Haseltine W Sodrosky J Changes in the transmembrane region of the human immunodeficiency virus type 1 gp4l envelope glycoprotein affect membrane fusion J Virol 1990, 64:6314-6318. 248812 2243396
25. Rapaport D Shai Y Interaction of fluorescently labeled pardaxin and its analogues with lipid bilayers J Biol Chem 1991, 266:23769-23775. 1748653
26. Kantchev EAB Cheng SF Wu CW Huang HJ Chang DK Secondary structure, phospholipid membrane interactions, and fusion activity of two glutamate-rich analogs of influenza hemagglutinin fusion peptide Arch Biochem Biophys 2004, 425:173-183. 10.1016/j.abb.2004.01.024 15111125
27. Lakowicz JR Principles of Fluorescence Spectroscopy New York: Plenum Press 1983.
28. Wu CW Cheng SF Huang WN Trivedi VD Veeramuthu B Kantchev AB Wu WG Chang DK Effects of alterations of the amino-terminal glycine of influenza hemagglutinin fusion peptide on its structure, organization and membrane interactions Biochim Biophys Acta 2003, 1612:41-51. 10.1016/ S0005-2736(03)00084-1 12729928
29. Van der Meer BW Coker G III Chen SYS Resonance Energy Transfer: Theory and Data New York: VCH Press 1994.
30. Morris SJ Bradley D Blumenthal R The use of cobalt ions as a collisional quencher to probe surface-charge and stability of fluorescently labeled bilayer vesicles Biochim Biophys Acta 1985, 818:365-372. 10.1016/ 0005-2736(85)90011-2 4041444
31. Bacigalupo MA Ius A Longhi R Meroni G Homogeneous immunoassay of atrazine in water by terbium-entrapping liposomes as fluorescent markers Talanta 2003, 61:539-545. 10.1016/S0039-9140(03)00320-5
32. Sainz B Jr Rausch JM Gallaher WR Garry RF Identification and characterization of the putative fusion peptide of the severe acute respiratory syndrome-associated coronavirus spike protein J Virol 2005, 79:7195-7206. 1112137 15890958 10.1128/JVI.79.11.7195-7206.2005
33. Tamm LK Tatulian SA Infrared spectroscopy of proteins and peptides in lipid bilayers Q Rev Biophys 1997, 30:365-429. 10.1017/S0033583597003375 9634652
34. Harrick NJ Internal Reflection Spectroscopy New York: Harrick Scientific Corporation 1967.
35. Tamm LK Tatulian SA Orientation of functional and nonfunctional PTS permease signal sequences in lipid bilayers. A polarized attenuated total reflection infrared study Biochemistry 1993, 32:7720-7726. 10.1021/ bi00081a017 8347581
36. Fung BKK Stryer L Surface density determination in membranes by fluorescence energy transfer Biochemistry 1978, 17:5241-5248. 10.1021/ bi00617a025 728398