Investigating fixative-induced changes in RNA quality and utility by microarray analysis

Experimental and Molecular Pathology

Volumn 84, Issue 2, 2008, Pages 156-172

  Cox, Melissa L ^a   Eddy, Susan M ^a   Stewart, Zachary S ^a   Kennel, Maggi R ^a   Man, Michael Z ^a   Paulauskis, Joseph D ^a   Dunstan, Robert W ^a  

^a PFIZER INC   (United States)

Author keywords

Degradation; Ethanol; Fixation; Formalin; Fragmentation; Gene expression; Laser microdissection; Microarray; Modified methacarn; RNA

Indexed keywords

ALCOHOL; FIXATIVE; FORMALDEHYDE; METHACARN; NUCLEIC ACID; PARAFFIN; RNA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FROZEN SECTION; GENOME ANALYSIS; LASER MICRODISSECTION; MICROARRAY ANALYSIS; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION;

ACETIC ACID; ANIMALS; ARTIFACTS; CHLOROFORM; ETHANOL; FIXATIVES; FORMALDEHYDE; LASERS; LIVER; METHANOL; MICRODISSECTION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARAFFIN EMBEDDING; RATS; RATS, SPRAGUE-DAWLEY; RNA, COMPLEMENTARY; TIME FACTORS; TISSUE FIXATION;

RATTUS;

EID: 40949145693     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2007.11.002     Document Type: Article

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