Impact of oxygenator characteristics on its capability to remove gaseous microemboli

Journal of Extra-Corporeal Technology

Volumn 39, Issue 4, 2007, Pages 271-273

  De Somer, Filip ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

CPB circuits; Gaseous emboli; Oxygenators

Indexed keywords

AIR EMBOLISM; BLOOD FLOW VELOCITY; BLOOD VESSEL OCCLUSION; CARDIOPULMONARY BYPASS; CONFERENCE PAPER; DISSOLUTION; ENDOTHELIUM LESION; EXTRACORPOREAL OXYGENATION; FILTER; FRACTIONATION; GAS EMBOLISM; HUMAN; MICROEMBOLISM; OUTCOME ASSESSMENT; OXYGENATOR; PATHOPHYSIOLOGY; INSTRUMENTATION; ISCHEMIA; METABOLISM; REVIEW; RISK FACTOR;

NITROGEN;

CARDIOPULMONARY BYPASS; EMBOLISM, AIR; EXTRACORPOREAL MEMBRANE OXYGENATION; HUMANS; ISCHEMIA; NITROGEN; OXYGENATORS, MEMBRANE; RISK FACTORS;

EID: 40949143237     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (29)

1. Blauth CI. Macroemboli and microemboli during cardiopulmonary bypass. Ann Thorac Surg. 1995;59:1300-3.
2. Dewanjee MK. Stroke from heparin-coated circuits and reduced systemic anticoagulation. Ann Thorac Surg. 1997;64:1218-9.
3. Johnston WE, Stump DA, DeWitt DS, et al. Significance of gaseous microemboli in the cerebral circulation during cardiopulmonary bypass in dogs. Circulation. 1993;88:II319-29.
4. Kurusz M, Butler BD. Bubbles and bypass: An update. Perfusion. 2004;19:S49-55.
5. Blauth CI, Smith PL, Arnold JV, Jagoe JR, Wootton R, Taylor KM. Influence of oxygenator type on the prevalence and extent of microembolic retinal ischemia during cardiopulmonary bypass: Assessment by digital image analysis. J Thorac Cardiovasc Surg. 1990;99:61-9.
6. Kincaid EH, Jones TJ, Stump DA, et al. Processing scavenged blood with a cell saver reduces cerebral lipid microembolization. Ann Thorac Surg. 2000;70:1296-300.
7. Mitchell SJ, Willcox T, Gorman DF. Bubble generation and venous air filtration by hard-shell venous reservoirs: a comparative study. Perfusion. 1997;12:325-33.
8. Massimino R, Gough J, Stearns G, Martin J. Gaseous emboli removal efficiency in arterial screen filters. A comparative study. J Extra Corpor Technol. 1984;15:25-34.
9. Clark RE, Margraf HW, Beauchamp RA. Fat and solid filtration in clinical perfusions. Surgery. 1975;77:216-24.
10. Dickinson TA, Riley JB, Crowley JC, Zabetakis PM. In vitro evaluation of the air separation ability of four cardiovascular manufacturer extracorporeal circuit designs. J Extra Corpor Technol. 2006;38:206-13.
11. Willcox TW, Mitchell SJ, Gorman DF. Venous air in the bypass circuit: a source of arterial line emboli exacerbated by vacuum-assisted drainage. Ann Thorac Surg. 1999;68:1285-9.
12. Willcox TW, Mitchell SJ. Arterial bubbles from the venous line. J Extra Corpor Technol. 2006;38:214-5.
13. Borger MA, Feindel CM. Cerebral emboli during cardiopulmonary bypass: effect of perfusionist interventions and aortic cannulas. J Extra Corpor Technol. 2002;34:29-33.
14. Borger MA, Peniston CM, Weisel RD, Vasiliou M, Green RE, Feindel CM. Neuropsychologic impairment after coronary bypass surgery: Effect of gaseous microemboli during perfusionist interventions. J Thorac Cardiovasc Surg. 2001;121:743-9.
15. Lindner JR, Coggins MP, Kaul S, Klibanov AL, Brandenburger GH, Ley K. Microbubble persistence in the microcirculation during ischemia/ reperfusion and inflammation is caused by integrin- and complement-mediated adherence to activated leukocytes. Circulation. 2000;101:668-75.
16. Bull JL. Cardiovascular bubble dynamics. Crit Rev Biomed Eng. 2005;33:299-346.
17. Barak M, Katz Y. Microbubbles: Pathophysiology and clinical implications. Chest. 2005;128:2918-32.
18. Dexter F, Hindman BJ. Computer simulation of microscopic cerebral air emboli absorption during cardiac surgery. Undersea Hyperb Med. 1998;25:43-50.
19. Dexter F, Hindman BJ. Recommendations for hyperbaric oxygen therapy of cerebral air embolism based on a mathematical model of bubble absorption. Anesth Analg. 1997;84:1203-7.
20. Grist G. Gaseous microemboli and hyperoxia. J Extra Corpor Technol. 2006;38:367-9.
21. Norman MJ, Sistino JJ, Acsell JR. The effectiveness of low-prime cardiopulmonary bypass circuits at removing gaseous emboli. J Extra Corpor Technol. 2004;36:336-42.
22. De Somer F, Dierickx P, Dujardin D, Verdonck P, Van Nooten G. Can an oxygenator design potentially contribute to air embolism in cardiopulmonary bypass? A novel method for the determination of the air removal capabilities of neonatal membrane oxygenators. Perfusion. 1998;13:157-63.
23. Weitkemper HH, Oppermann B, Spilker A, Knobl HJ, Korfer R. Gaseous microemboli and the influence of microporous membrane oxygenators. J Extra Corpor Technol. 2005;37:256-64.
24. Mitsumaru A, Yozu R, Matayoshi T, et al. Efficiency of an air filter at the drainage site in a closed circuit with a centrifugal blood pump: An in vitro study. ASAIO J. 2001;47:692-5.
25. Matayoshi T, Yozu R, Morita M, Shin H, Mitsumaru A, Kawada S. Development of a completely closed circuit using an air filter in a drainage circuit for minimally invasive cardiac surgery. Artif Organs. 2000;24:454-8.
26. Eitschberger S, Henseler A, Krasenbrink B, Oedekoven B, Mottaghy K. Investigation on the ability of an ultrasound bubble detector to deliver size measurements of gaseous bubbles in fluid lines by using a glass bead model. ASAIO J. 2001;47:18-24.
27. Willcox TW, Mitchell SJ. The influence of vacuum assisted drainage on arterial line emboli. J Extra Corpor Technol. 2002;34:228-9.
28. Willcox TW. Vacuum-assisted venous drainage: To air or not to air, that is the question. Has the bubble burst? J Extra Corpor Technol. 2002;34:24-8.
29. Tovar EA, Del Campo C, Borsari A, Webb RP, Dell JR, Weinstein PB. Postoperative management of cerebral air embolism: Gas physiology for surgeons. Ann Thorac Surg. 1995;60:1138-42.