The influence of immunosuppression on the development of BK virus nephropathy-Does it matter?

Nephrology Dialysis Transplantation

Volumn 22, Issue SUPPL.8, 2007, Pages

  Beimler, Jörg ^a   Sommerer, Claudia ^b   Zeier, Martin ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b NONE

Author keywords

BK virus nephritis; BK virus nephropathy; Immunosuppression; Polyomavirus; Renal transplantation

Indexed keywords

IMMUNOSUPPRESSIVE AGENT;

BK VIRUS; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; REVIEW; TREATMENT OUTCOME; VIROLOGY; VIRUS INFECTION;

BK VIRUS; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; IMMUNE TOLERANCE; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; POLYOMAVIRUS INFECTIONS; TREATMENT OUTCOME;

EID: 40949138248     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfm646     Document Type: Conference Paper

References (33)

1. Gardner SD, Field AM, Coleman DV, Hulme B. New human papovavirus (B.K.) isolated from urine after enal transplantation. Lancet 1971; 19: 1253-1257
2. Nickeleit V, Hirsch HH, Binet IF et al. Polyomavirus infection of renal allograft recipients: from latent infection to manifest disease. J Am Soc Nephrol 1999; 10: 1080-1089 (Pubitemid 29203096)
3. Ramos E, Drachenberg CB, Papadimitriou JC et al. Clinical course of polyoma virus nephropathy in 67 renal transplant patients. J Am Soc Nephrol 2002; 13: 2145-2151 (Pubitemid 34790793)
4. Binet I, Nickeleit V, Hirsch HH et al. Polyomavirus disease under new immunosuppressive drugs: a cause of renal graft dysfunction and graft loss. Transplantation 1999; 67: 918-922 (Pubitemid 29169141)
5. Stolt A, Sasnauskas K, Koskela P et al. Seroepidemiology of the human polyomaviruses. J Gen Virol 2003; 84: 1499-1504 (Pubitemid 36675520)
6. Hirsch HH, Knowles W, Dickenmann Met al. Prospective study of polyomavirus type BK replication and nephropathy in renaltransplant recipients. N Engl J Med 2002; 347: 488-496 (Pubitemid 34879336)
7. Brennan DC, Agha I, Bohl DL et al. Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction. Am J Transplant 2005; 5: 582-594 (Pubitemid 40313351)
8. Drachenberg CB, Papadimitriou JC, Wali R et al. Improved outcome of polyoma virus allograft nephropathy with early biopsy. Transplant Proc 2004; 36: 758-759 (Pubitemid 38534382)
9. Wadei HM, Rule AD, Lewin M et al. Kidney transplant function and histological clearance of virus following diagnosis of polyomavirus-associated nephropathy. Am J Transplant 2006; 6: 1025
10. Drachenberg CB, Papadimitriou JC, Hirsch HH et al. Histological patterns of polyomavirus nephropathy: correlation with graft outcome and viral load. Am J Transplant 2004; 4: 2082-2092 (Pubitemid 39611638)
11. Nickeleit V, Klimkait T, Binet IF et al. Testing for polyomavirus type BK DNA in plasma to identify renalallograft recipients with viral nephropathy. N Engl J Med 2000; 342: 1309-1315 (Pubitemid 30408715)
12. Ding R, Medeiros M, Dadhania D et al. Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation 2002; 74: 987-994 (Pubitemid 35191249)
13. Smith JM, McDonald RA, Finn LS et al. Polyomavirus nephropathy in pediatric kidney transplant recipients. Am J Transplant 2004; 4: 2109-2117 (Pubitemid 39611641)
14. Bohl DL, Storch GA, Ryschkewitsch C et al. Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptability to sustained BK viremia. Am J Transplant 2005; 5: 2213-2221 (Pubitemid 41648468)
15. Hariharan S, Cohen EP, Vasudev B et al. BKV specific antibodies and BKV DNA in renal transplant recipients with BKV nephritis. Am J Transplant 2004; 4: 2109-2117
16. Comoli P, Azzi A, Maccario R et al. Polyomavirus BK-specific immunity after kidney transplantation. Transplantation 2004; 78: 1229-1232 (Pubitemid 39426446)
17. Atencio IA, Shadan FF, Zhou XJ et al. Adult mouse kidneys become permissive to acute polyomavirus infection and reactivate persistent infections in response to cellular damage and regeneration. J Virol 1993; 67: 1424-1432 (Pubitemid 23067649)
18. Buehrig CK, Lager DJ, Stegall MD et al. Influence of surveillance renal allograft biopsy on diagnosis and prognosis of polyomavirus-associated nephropathy. Kidney Int 2003; 64: 665-673 (Pubitemid 36871940)
19. Mengel M, Marwedel M, Radermacher J et al. Incidence of polyomavirus-nephropathy in renal allografts: influence of modern immunosuppressive drugs. Nephrol Dial Transplant 2003; 18: 1190-1196 (Pubitemid 36722523)
20. Barri YM, Ahmad I, Ketel BL et al. Polyoma viral infection in renal transplantation: the role of immunosuppressive therapy. Clin Transplant 2001; 15: 240-246 (Pubitemid 32725406)
21. Randhawa PS, Finkelstein S, Scantlebury V et al. Human polyoma virus-associated interstitial nephritis in the allograft kidney. Transplantation 1999; 67: 103-109 (Pubitemid 29061146)
22. Vasudev B, Hariharan S, Hussain SA et al. BK virus nephritis: risk factors, timing, and outcome in renal transplant recipients. Kidney Int 2005; 68: 1834-1839 (Pubitemid 43169929)
23. Lipshutz GS, Flechner SM, Govani MV, Vincenti F. BK nephropathy in kidney transplant recipients treated with a calcineurin inhibitor-free immunosuppression regimen. Am J Transplant 2004; 4: 2132-2134 (Pubitemid 39611644)
24. Vincenti F. Immunosuppression minimization: current and future trends in transplant immunosuppression. J Am Soc Nephrol 2003; 14: 1940-1948 (Pubitemid 36750490)
25. Trofe J, Roy-Chaudhury P, Gordon J et al. Early steroid cessation/avoidance regimens are associated with a lower incidence of polyomavirus nephropathy compared to steroid based immunosuppression in kidney transplant recipients. Am J Transplant 2003; 3: 371
26. Dadhania D, Muthukumar T, Snopkowski C et al. Epidemiology of BK virus replication in renal allograft recipients and identification of corticosteroid maintainance therapy as an independent risk factor. Am J Transplant 2004; 4: 198
27. Celik B, Shapiro R, Vats A, Randhawa PS. Polyomavirus allograft nephropathy: sequential assessment of histologic viral load, tubulitis, and graft function following changes in immunosuppression. Am J Transplant 2003; 3: 1378-1382 (Pubitemid 37288082)
28. Hirsch HH, Brennan DC, Drachenberg CB et al. Polyomavirusassociated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation 2005; 79: 1277-1286 (Pubitemid 40734783)
29. Wong W, Agrawal N, Pascual M et al. Comparison of two dosages of thymoglobulin used as a short-course for induction in kidney transplantation. Transpl Int 2006; 19: 629-635
30. Awadalla Y, Randhawa P, Ruppert K, Zeevi A, Duquesnoy RJ. HLA mismatching increases the risk of BK virus nephropathy in renal transplant recipients. Am J Transplant 2004; 4: 1691-1696 (Pubitemid 39312305)
31. Trofe J, Cavallo T, First MR et al. Polyomavirus in kidney and kidney-pancreas transplantation: a defined protocol for immunosuppression reduction and histologic monitoring. Transplant Proc 2002; 34: 1788-1789
32. Cosio FG, Amer H, Grande JP et al. Comparison of low versus high tacrolimus levels in kidney transplantation: assessment of efficacy by protocol biopsies. Transplantation 2007; 83: 411-416 (Pubitemid 46667844)
33. Namba Y, Moriyama T, Kyo M et al. Prevalence, characteristics, and outcome of BK virus nephropathy in Japanese renal transplant patients: analysis in protocol and episode biopsies. Clin Transplant 2005; 19: 97-101 (Pubitemid 40227859)