Hormonal resuscitation therapy in the management of the brain-dead potential organ donor

International Journal of Surgery

Volumn 6, Issue 1, 2008, Pages 3-4

  Cooper, David K C ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGIPRESSIN; BICARBONATE; HYDROCORTISONE; INSULIN; LIOTHYRONINE; METHYLPREDNISOLONE; THYROTROPIN; THYROXINE;

BRAIN BLOOD VESSEL; BRAIN DEATH; BRAIN DYSFUNCTION; CATECHOLAMINE RELEASE; CLINICAL TRIAL; EDITORIAL; GRAFT RECIPIENT; HEART MUSCLE INJURY; HEART TRANSPLANTATION; HORMONAL RESUSCITATION THERAPY; HORMONAL THERAPY; HUMAN; LIOTHYRONINE BLOOD LEVEL; LUNG INJURY; NONHUMAN; ORGAN DONOR; PRIORITY JOURNAL; THYROXINE BLOOD LEVEL; VASCULAR RESISTANCE; VASOCONSTRICTION;

BRAIN DEATH; GRAFT REJECTION; HEART TRANSPLANTATION; HORMONE REPLACEMENT THERAPY; HORMONES; HUMANS; RESUSCITATION; TISSUE DONORS;

EID: 40949134175     PISSN: 17439191     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijsu.2006.11.007     Document Type: Editorial

References (17)

1. Novitzky D., Cooper D.K.C., Rosendale J.D., and Kauffman H.M. Hormonal therapy of the brain-dead organ donor: experimental and clinical studies. Transplantation 82 (2006) 1396-1401
2. Novitzky D., Wicomb W.N., Cooper D.K.C., Rose A.G., Fraser R.C., and Barnard C.N. Electrocardiographic, haemodynamic and endocrine changes occurring during experimental brain death in the chacma baboon. J Heart Transplant 4 (1984) 63-69
3. Novitzky D., Horak A., Cooper D.K.C., and Rose A.G. Electrocardiographic and histopathologic changes developing during experimental brain death in the baboon. Transplant Proc 21 (1989) 2567-2569
4. Cooper D.K.C., Novitzky D., and Wicomb W.N. The pathophysiological effects of brain death on potential donor organs, with particular reference to the heart. Ann R Coll Surg Engl 71 (1989) 261-266
5. Novitzky D., Wicomb W.N., Rose A.G., Cooper D.K.C., and Reichart B. Pathophysiology of pulmonary edema following experimental brain death in the chacma baboon. Ann Thorac Surg 43 (1987) 288-294
6. Wicomb W.N., Cooper D.K.C., Lanza R.P., Novitzky D., and Isaacs S. The effects of brain death and 24 hours storage by hypothermic perfusion on donor heart function in the pig. J Thorac Cardiovasc Surg 91 (1986) 896-909
7. Novitzky D., Cooper D.K.C., Morrell D., and Isaacs S. Change from aerobic to anaerobic metabolism after brain death, and reversal following triiodothyronine therapy. Transplantation 45 (1988) 32-36
8. Novitzky D., Wicomb W.N., Cooper D.K.C., and Tjaalgard M.A. Improved cardiac function following hormonal therapy in brain dead pigs: relevance to organ donation. Cryobiology 24 (1987) 1-10
9. Novitzky D., Cooper D.K.C., and Reichart B. Hemodynamic and metabolic responses to hormonal therapy in brain-dead potential organ donors. Transplantation 43 (1987) 852-854
10. Rosengard B.R., Feng S., Alfrey E.J., Zaroff J.G., Emond J.C., Henry M.L., et al. Report of the Crystal City meeting to maximize the use of organs recovered from the cadaver donor. Am J Transplant 2 (2002) 701-711
11. Rosendale J.D., Chabalewski F.L., McBride M.A., Garrity E.R., Rosengard B.R., Delmonica F.L., et al. Increased transplanted organs from the use of a standardized donor management protocol. Am J Transplant 2 (2002) 761-768
12. Rosendale J.D., Kauffman H.M., McBride M.A., Chabalewski F.L., Zaroff J.G.., Garrity E.R., et al. Aggressive pharmacological donor management results in more transplanted organs. Transplantation 75 (2003) 482-487
13. Rosendale J.D., Kauffman H.M., McBride M.A., Chabalewski F.L., Zaroff J.G.., Garrity E.R., et al. Hormonal resuscitation yields more transplanted hearts with improved early function. Transplantation 75 (2003) 1336-1341
14. Novitzky D., Human P.A., and Cooper D.K.C. Inotropic effect of triiodothyronine following myocardial ischaemia and cardiopulmonary bypass: an experimental study in pigs. Ann Thorac Surg 45 (1988) 50-55
15. Novitzky D., Human P.A., and Cooper D.K.C. Effect of triiodothyronine (T3) on myocardial high energy phosphates and lactate following ischemia and cardiopulmonary bypass - an experimental study in baboons. J Thorac Cardiovasc Surg 96 (1988) 600-607
16. Novitzky D., Cooper D.K.C., Human P.A., Reichart B., and Zuhdi N. Triiodothyronine therapy for heart donor and recipient. J Heart Transplant 7 (1988) 370-376
17. Novitzky D., Cooper D.K.C., Chaffin J.S., Greer A.E., Debault L.E., and Zuhdi N. Improved cardiac allograft function following triiodothyronine therapy to both donor and recipient. Transplantation 49 (1990) 311-316