Coenzyme Q10 Depletion: Etiopathogenic or Predisposing Factor in Statin Associated Myopathy?

American Journal of Cardiology

Volumn 101, Issue 7, 2008, Pages 1071-

  Chatzizisis, Yiannis S ^a   Vaklavas, Christos ^a   Giannoglou, George D ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN; UBIDECARENONE;

DIET SUPPLEMENTATION; DISEASE PREDISPOSITION; DRUG MEGADOSE; HUMAN; LETTER; MYOPATHY; PATHOGENESIS; PRIORITY JOURNAL;

COENZYMES; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MUSCULAR DISEASES; TREATMENT OUTCOME; UBIQUINONE; VITAMINS;

EID: 40949131396     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2007.12.005     Document Type: Letter

References (4)

1. Young J.M., Florkowski C.M., Molyneux S.L., McEwan R.G., Frampton C.M., George P.M., and Scott R.S. Effect of coenzyme q(10) supplementation on simvastatin-induced myalgia. Am J Cardiol 100 (2007) 1400-1403
2. Caso G., Kelly P., McNurlan M.A., and Lawson W.E. Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. Am J Cardiol 99 (2007) 1409-1412
3. Marcoff L., and Thompson P.D. The role of coenzyme Q10 in statin-associated myopathy: a systematic review. J Am Coll Cardiol 49 (2007) 2231-2237
4. Paiva H., Thelen K.M., Van Coster R., Smet J., De Paepe B., Mattila K.M., Laakso J., Lehtimaki T., von Bergmann K., Lutjohann D., and Laaksonen R. High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial. Clin Pharmacol Ther 78 (2005) 60-68