From in vitro blood rheology to useful bedside instrumentation for cardiovascular diseases: History and challenges

Annals of Biomedical Engineering

Volumn 36, Issue 4, 2008, Pages 528-533

  Frojmovic, Maurice Mony ^a,b  

^a Scientific Advisory Commitee ^*

^b Drexma Reocito Inc

Author keywords

Antithrombotic drugs; Bedside flow devices; Flow cytometry; In vitro blood rheology; Individualized medicine; Microrheology; Platelet function analyzers; Point of care instrumentation for cardiovascular diseases

Indexed keywords

DISEASES; DRUG DOSAGE; FLOW CYTOMETRY; RHEOLOGY;

ANTITHROMBOTIC DRUGS; BLOOD RHEOLOGY; FLOW DEVICES; MICRORHEOLOGY; PLATELET FUNCTION ANALYZERS;

PLATELETS;

BIOMEDICAL TECHNOLOGY ASSESSMENT; BLOOD; BLOOD RHEOLOGY; CARDIOVASCULAR DISEASE; DRUG MONITORING; EQUIPMENT DESIGN; FLOW CYTOMETRY; HISTORY; HOSPITAL INFORMATION SYSTEM; HUMAN; INSTRUMENTATION; METHODOLOGY; MICROFLUIDIC ANALYSIS; REVIEW;

CARDIOVASCULAR DISEASES; DRUG MONITORING; EQUIPMENT DESIGN; FLOW CYTOMETRY; HEMORHEOLOGY; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; POINT-OF-CARE SYSTEMS; TECHNOLOGY ASSESSMENT, BIOMEDICAL;

EID: 40949118457     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-008-9466-3     Document Type: Article

References (26)

1. Ajzenberg N., Aubry P., Huisse M.-G., Cachier A., ElAmara W., Feldman L., Himbert D., Baruch D., Guillin M.-C., Steg G. (2005) Enhanced shear-induced platelet aggregation in patients who experience subacute stent thrombosis. A case-control study. J. Am. College Cardiol. 45(11):1753
2. Bonnefoy A., Hantgan R., Legrand C., Frojmovic M. M. (2001) A model of platelet aggregation involving multiple ineteractions of thrombospondin-1, fibrinogen and GPIIbIIIa receptor. J. Biol. Chem. 276: 5605-5612
3. Bonnefoy A., Liu Q., Jerome W. G., Legrand C., Frojmovic M. M. (2001) Platelets in suspension require preactivation to adhere to immobilized fibrinogen. Annl. NY Acad. Sci. 936: 459-463
4. Frojmovic M. M. (1975) Rheooptical studies of blood cells. Biorheology 12: 193-202
5. Frojmovic M. M. (1978) Rheooptical studies of platelet structure and function. Progr Hemost. Thromb. 4: 279-319
6. Frojmovic M. M. (1998) Platelet aggregation in flow: differential roles for adhesive receptors and ligands. Am. Heart J. Suppl. 135: 5119-5131
7. Frojmovic M. M., Kasirer-Friede A., Goldsmith H., Brown E. (1997) Surface-secreted von Willebrand factor mediates aggregation of ADP-activated platelets at moderate shear stress: facilitated by GPIb but controlled by GPIIb-IIIa. Thromb. Haemost. 76: 568-576
8. Frojmovic, M. M., G. Nash, and S. L. Diamond. Definitions in biorheology: cell aggregation and cell adhesion in flow. Recommendation of the Scientific Subcommittee on Biorheology of the Scientific and Standardisation Committee (SSC) of the International Society on Thrombosis and Haemostasis (ISTH). Thromb. Haemost. 87(4):771, 2002 (full text at ISTH website: www.unc.edu/isth/subcomm. thm )
9. Frojmovic, M., P. Theroux, M. Angioi, and M.Ghitescu. Inter-individual variability in inhibition of platelet activation and aggregation by clopidogrel. J. Thromb. Haemost. 1(Suppl 1):P0235, 2003
10. Frojmovic M. M., Wong T, van de Ven T. G. M. (1991) Damic measurements of the platelet membrane glycoprotein αIIbβ3 receptor for fibrinogen by flow cytometry. I. Methodology, theory and results for two distinct activators. Biophys. J. 59: 815-827
11. Frojmovic, M., and E. Zolotarova. Both shear and temperature can profoundly alter antithrombotic drug efficacy: demonstration with the P2Y12 ADP receptor antagonist, ARC-69931MX. J. Thromb. Haemost. 1(Suppl 1):1772, 2003
12. Goldsmith H. L., Frojmovic M. M., Braovac S., McIntosh F., Wong T. (1994) Thromb. Haemost. 71: 78-90
13. Goldsmith H. L., McIntosh F. A., Shahin J., Frojmovic M. M. (2000) Time and force dependence of the rupture of glycoprotein IIb-IIIa fibrinogen bonds between latex spheres. Biophys. J. 78:1195-1206
14. Hu D. D., White C. A., Panzer-Knodle S., Page J. D., Nicholson N., Smith J. W. (1999) A new model of dual interacting ligand binding sites on integrin IIb/IIIa. J. Biol. Chem. 274(8):4633-4639
15. Karino T., Goldsmith H. L. (1979) Aggregation of human platelets in an annular vortex distal to a tubular expansion, Microvasc. Res. 17:217-237
16. Kasirer-Friede A., Legrand C., Frojmovic M. M. (2001) Complementary roles for fibrin(ogen), thrombospondin and von Willebrand factor in mediating shear-dependent aggregation of platelets stimulated at threshold thrombin concentrations. Thromb. Haemost. 86: 653-659
17. Labarthe B., Frojmovic M., Legrand C. (2005) Inhibition and reversal of platelet aggregation by αIIbβ3 antagonists depends on flow conditions: differential effects of Abciximab and Lamifiban. Br. J. Haematol. 131:348-355
18. Mason S. G. (1979) How I became interested in Colloid Science. J. Colloid Interf. Sci. 71: 8-10
19. Varki A. (2007) Trousseau's syndrome: multiple definitions and multiple mechanisms. Blood 110(6):1723-1729
20. Verstraete M. (2000) Synthetic inhibitors of Glycoprotein IIb/IIIa in clinical development. Circulation 101:e76
21. Xia Z., Frojmovic M. M. (1994) Aggregation efficiency of activated normal or fixed platelets in a simple shear field: effect of shear and fibrinogen occupancy. Biophys. J. 66: 2110-2201
22. Xiao Z., Théroux P., Frojmovic M. (1999) Modulation of platelet-neutrophil interaction with pharmacological inhibition of fibrinogen binding to platelet GPIIb/IIIa receptor. Thromb. Haemost. 81: 281-285
23. Yung, W., and M. Frojmovic. Platet aggregation in laminar flow. II. Shear rate and ADP-dependent effects of acetylsalicylic acid and indomethacin. Thromb. Res. 28:379-387, 1982
24. Yung W., Frojmovic M. (1982) Platelet aggregation in laminar flow. I. Adenosine diphosphate concentration, time and shear rate dependence. Thromb. Res. 28: 361-377
25. Zwaginga J. J., Nash G., King M. R., Heemskerk J. W. M., Frojmovic M., Hoylaerts M. F., Sakariassen K. S. (2006) Flow-based assays for global assessment of hemostasis. Part 1: biorheologic considerations. Thromb. Haemost. 4(11):2486-2487
26. Zwaginga J. J., Sakariassen K. S., Nash G., King M. R., Heemskerk J. W., Frojmovic M., Hoylaerts M. F. (2006) Flow-based assays for global assessment of hemostasis. Part 2: current methods and considerations for the future. Thromb. Haemost. 4(12): 2716-2717