First-line therapy with latanoprost 0.005% results in improved ocular circulation in newly diagnosed primary open-angle glaucoma patients: A prospective, 6-month, open-label study

Eye

Volumn 22, Issue 3, 2008, Pages 363-369

  Gherghel, D ^a,b   Hosking, S L ^a,b   Cunliffe, I A ^b   Armstrong, R A ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LATANOPROST;

ADULT; AGED; ARTICLE; BLOOD FLOW VELOCITY; BLOOD FLOWMETRY; BLOOD VOLUME; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; EYE BLOOD FLOW; FEMALE; FOLLOW UP; HUMAN; INTRAOCULAR PRESSURE; LONGITUDINAL STUDY; MALE; OPEN ANGLE GLAUCOMA; OPEN STUDY; OPTIC NERVE; OPTICAL TOMOGRAPHY; PRESSURE MEASUREMENT; PRIMARY GLAUCOMA; PROSPECTIVE STUDY; RETINA BLOOD FLOW; SYSTOLIC BLOOD PRESSURE;

EID: 40949113252     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/sj.eye.6702639     Document Type: Article

References (64)

1. Rolanapongpun P, Drance SM, Morrison BJ. Ophthalmic artery flow velocity in glaucomatous and normal subjects. Br J Ophthalmol 1993; 77 25-29.
2. Plange N, Kaup M, Arend O, Remky A. Asymmetric visual field loss and retrobulbar haemodynamics in primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol 2006; 244(8): 978-983.
3. Nicolela MT, Hnik P, Drance SM. Scanning laser Doppler flowmeter study of retinal and optic disk blood flow in glaucomatous patients. Am J Ophthalmol 1996; 122: 775-783.
4. Kaiser HJ, Schötzau A, Stümpfig D, Flammer J. Blood-flow velocities of the extraocular vessels in patients with high-tension and normal-tension primary open-angle glaucoma. Am J Ophthalmol 1997; 123: 320-327.
5. Butt Z, O'Brien C, McKillop G, Aspinall P, Allan P. Color Doppler imaging in untreated high- and normal-pressure open-angle glaucoma. Invest Ophthalmol Vis Sci 1997; 38: 690-696.
6. Findl O, Rainer G, Dallinger S, Dorner G, Polak K, Kiss B et al. Assessment of optic disk blood flow in patients with open-angle glaucoma [In Process Citation]. Am J Ophthalmol 2000; 130: 589-596.
7. Gherghel D, Orgül S, Gugleta K, Gekkieva M, Flammer J. Relationship between ocular perfusion pressure and retrobulbar circulation in glaucoma patients with progressive damage. Am J Ophthalmol 2000; 130: 597-605.
8. Sogano S, Tomita G, Kitazawa Y. Changes in retinal nerve fiber layer thickness after reduction of intraocular pressure in chronic open-angle glaucoma. Ophthalmology 1993; 100: 1253-1258.
9. Emre M, Orgul S, Gugleta K, Flammer J. Ocular blood flow alteration in glaucoma is related to systemic vascular dysregulation. Br J Ophthalmol 2004; 88: 662-666.
10. Susanna R, Basseto FL. Hemorrhage of the optic disc and eurosensorial dysacousia. J Glaucoma 1992; 1: 248-253.
11. Kaiser HJ, Flammer J, Graf T, Stümpfig D. Systemic blood pressure in glaucoma patients. Graefe's Arch Clin Exp Ophthalmol 1993; 231 677-680.
12. Kaiser HJ, Flammer J, Burckhardt D. Silent myocardial ischemia in glaucoma patients. Ophthalmologica 1993; 207: 6-7.
13. Bechetoille A, Bresson-Dumont H. Diurnal and nocturnal blood pressure drops in patients with focal ischemic glaucoma. Graefe's Arch Clin Exp Ophthalmol 1994; 232: 675-679.
14. Weinstein JM, Funsch D, Page RB, Brennan RW. Optic nerve blood flow and its regulation. Invest Ophthalmol Vis Sci 1982; 23: 640-645.
15. Graham SL, Drance SM, Wijsman K, Douglas GR, Mikelberg FS. Ambulatory blood pressure monitoring in glaucoma. The nocturnal dip. Ophthalmology 1995; 102: 61-69.
16. Stroman GA, Stewart WC, Golnik KC, Cure JK, Olinger RE. Magnetic resonance imaging in patients with low-tension glaucoma. Arch Ophthalmol 1995; 113: 168-172.
17. Waldmann E, Gasser P, Dubler B, Huber C, Flammer J. Silent myocardial ischemia in glaucoma and cataract patients. Graefe's Arch Clin Exp Ophthalmol 1996; 234: 595-598.
18. O'Brien C, Butt Z. Blood flow velocity in the peripheral circulation in glaucoma patients. Ophthalmologica 1999; 213: 150-153.
19. Kashiwagi K, Tsumura T, Ishii H, Ijiri H, Tamura K, Tsukahara S. Circadian rhythm of autonomic nervous function in patients with normal-tension glaucoma compared with normal subjects using ambulatory electrocardiography. J Glaucoma 2000, 9: 239-246.
20. Kashiwagi Hosaka O, Kashiwagi F, Taguchi K, Mokiyuki J, Ishii H et al Systemic circulatory parameters comparison between patients with normal tension glaucoma and normal subject using ambulatory monitoring. Jpn J Ophthalmol 2001; 45: 388-396.
21. Harris A, Spaeth GL, Sergott RC, Katz LJ, Cantor LB, Martin BJ. Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma. Am J Ophthalmol 1995; 120: 168-175.
22. Yoshida A, Ogasawara H, Fujio N, Konno S, Ishiko S, Kitaya N et al Comparison of short- and long-term effects of betaxolol and timolol on human retinal circulation. Eye 1998; 12: 848-853.
23. Sponsel WA, Terry S, Khuu HD, Lam KW, Frenzel H. Periocular accumulation of timolol and betaxolol in glaucoma patients under long-term therapy. Surv Ophthalmol 1999; 43(Suppl): S210-S213.
24. Bergstrand IC, Heijl A, Wollmer P, Hansen F, Harris A. Timolol increases retrobulbar flow velocities in untreated glaucoma eyes but not in ocular hypertension. Acta Ophthalmol Scand 2001; 79: 455461.
25. Vetrugno M, Maino A, Cantatore F, Ruggeri G, Cardia L. Acute and chronic effects of brimonidine 0 2 on intraocular pressure and pulsatile ocular blood flow in patients with primary opert-angle glaucoma: An open-label, uncontrolled, prospective study. Clin Ther 2001; 23: 1519-1528.
26. Martinez A, Gonzales F, Capeans C, Perez R, Sanchez-Salorio M. Dorzolamide effect on ocular blod flow. Invest Ophthalmol Vis Sci 1999; 40: 1270-1275.
27. Harris A, Arend O, Kagemann L, Garrett M, Chung HS, Martin B. Dorzolamide, visual function and ocular hemodynamics in J Ocul Pharmacol Ther 1999; 15: 189-197.
28. Bernd AS, Pillunat LE, Bohm AG, Schmidt KG, Richard G. Ocular hemodynamics and visual field in glaucoma treated with dorzolamide. Ophthalmologe 2001; 98: 451-455.
29. Galassi F, Socii A, Rertieri G, Ucci F, Pieri B, Harris A et al. Effects of timolol and dorzolamide on retrobulbar hemodynamics in patients with newly diagnosed primary open-angle glaucoma. Ophthalmologica 2002; 216: 123-128.
30. Ishii K, Tomidokoro A, Nagahara M, Tamaki Y. Kanno M, Fukaya Y et al Effects of topical latanoprost on optic nerve head circulation in rabbits, monkeys and humans. Invest Ophthalmol Vis Sci 2001; 42 2957-2963.
31. Tamaki Y, Nagahara M, Araie M, Tomita K, Sandoh S, Tomidokoro A. Topical latanoprost and optic nerve head and retinal circulation in humans. J Ocular Pharmacol Therap 2001; 17: 403-411.
32. Vetrugno M, Cantatore F, Gigante G, Cardia L. Latanoprost 0.005% in POAG: Effects on IOP and ocular blood flow. Acta Ophthalmol Scand Suppl 1998; 227: 40-41.
33. McKibbin M, Menage MJ. The effect of once-daily latanoprost an intraocular pressure and pulsatile ocular blood flow in normal tension glaucoma. Eye 1999; 13: 31-34.
34. Geyer O, Man O, Weintraub M, Silver DM. Acute effect of latanoprost on pulsatile ocular blood flow in normal eyes. Am J Ophthalmol 2001; 131: 198-202.
35. Georgopoulos GT, Diestelhorst M, Fisher R, Ruokonen P, Krieglstein GK The short-term effect of latanoprost on intraocular pressure and pulstatile ocular blood flow. Acta Ophthalmol Scand 2002; 80 54-58.
36. Michelson G, Schmauss B. Two dimensional mapping of the perfusion of the retina and optic nerve head. Br J Ophthalmol 1995; 79: 1126-1132.
37. Michelson G, Langhans MJ, Groh MJ, Clinical investigation of the combination of a scanning laser ophthalmoscope and laser Doppler flowmeter. Ger J Ophthalmol 1995; 4: 342-349.
38. Burk RO, Rohrschneider K, Noack H, Volcker HE. Are large optic nerve heads susceptible to glaucomatous damage at normal intraocular pressure? A three-dimensional study by laser scanning, tomography. Graefe's Arch Clin Exp Ophthalmol 1992; 230: 552-560.
39. Burk RO, Rohrschneider K, Takamoto T, Volcker HE, Schwartz B. Laser scanning tomography and stereophotogrammetry in three-dimensional optic disc analysis. Graefe's Arch Clin Exp Ophthalmol 1993; 231: 193-198.
40. Rohrschneider K, Burk RO, Volcker HE. Reproducibility of topometric data acquisition in normal and glaucomatous optic nerve heads with the laser tomographic scanner. Graefe's Arch Clin Exp Ophthalmol 1993; 231: 457-464.
41. Bartz-Schmidt KU, Weber J, Heimann K. Validity of two dimensional data obtained with the Heidelberg retina tomograph as verified by direct measurements in normal optic nerve heads. Ger J Ophthalmol 1994; 3: 400-405.
42. Iester M, Mikelberg FS, Drance SM. The effect of optic disc size on diagnostic precision with the Heidelberg Retina Tomograph. Ophthalmology 1997; 104: 545-548.
43. Iester M, Broadway DC, Mikelberg FS, Drance SM. A comparison of healthy, ocular hypertensive, and glaucomatous optic disc topographic parameters. J Glaucoma 1997; 6: 363-370.
44. Jonescu-Cuypers CP, Thumann G, Hilgers RD, Batz-Schmidt KU, Krott R, KriegIstein GK. Long-term fluctuations of the normalised rim/disc area ratio quotient in normal eyes. Graefe's Arch Clin Exp Ophthalmol 1999; 237: 181-186.
45. Weinreb RN, Lusky M, Bartsch DU, Morsman D. Effect of repetitive imaging on topographic measurements of the optic nerve head. Arch Ophthalmol 1993; 111: 636-638.
46. Saruhan A, Orgul S, Kocak I, Prunte C, Flammer J. Descriptive information of topographic parameters computed at the optic nerve head with the Heidelberg retina tomograph. J Glaucoma 1998; 7: 420-429.
47. Jonescu-Cuypers CP, Chung HS, Kagemenn L, Ishii Y, Zarfati D, Harris A. New neuroretinal rim blood flow evaluation method combining Heidelberg retina flowmetry and tomography. Br J Ophthalmol 2001; 85: 304-309.
48. Kagemann L, Harris A, Chung HS, Evans D, Buck S, Martin B. Heidelberg retinal flowmetry: Factors affecting blood flow measurement. Br J Ophthalmol 1998; 82: 131-136.
49. Hosking SL, Embleton S, Cunliffe IA. Application of a local search strategy improves the detection of blood flow deficits in the neuroretinal rim of glaucoma patients using scanning laser Doppler flowmetry. Br J Ophthalmol 2001; 85: 1298-1302.
50. Sehi M, Flanagan JG. The effect of image alignement on capillary blood flow measurement of the neuroretinal rim using the Heidelberg retina flowmeter. Br J Ophthalmol 2004; 88: 204-206.
51. Alm A, Villumsen J, Tornquist P, Mandahl A, Airaksinen J, Tuulonen A et al. Intraocular pressure-reducing effect of PhXA41 in patients with increased eye pressure. A one-month study [see comments]. Ophthalmology 1993; 100: 1312-1316.
52. Camras CB. The United States Latanoprost Study Group: Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: A six-month masked, multicenter trial in the United States. Ophthalmology 1996; 103: 138-147.
53. Drance SM, Crichton A, Mills RP Comparison of the effect of latanoprost 0.005% and timolol 0.5% on the calculated ocular perfusion pressure in patients with normal-tension glaucoma. Am J Ophthalmol 1998; 125: 585-592.
54. Liu CJ, Ko YC, Cheng CY, Chou JC, Hsu WM, Liu JH. Effect of latanoprost 0.005% and brimonidine tartrate 0.2% on pulsatile ocular blood flow in normal tension glaucoma. Br J Ophthalmol 2002; 86: 1236-1239.
55. Liu CJ, Ko YC, Cheng CY, Chiu AW, Chou JC, Hsu WM et al. Changes in intraocular pressure and ocular perfusion pressure after latanoprost 0.005 or brimonidine tartrate 0.2% in normal-tension glaucoma patients. Ophthalmology 2002; 109: 2241-2247.
56. Sugiyama K, Bacon DR, Cioffi GA, Fahrenback WH, Van Buskirk EM. The effects of phenylephrine on the ciliary body and optic nerve head microvasculature in rabbits. J Glaucoma 1992; 1: 156-164.
57. Inan UU, Ermis SS, Yucel A, Ozturk F. The effects of latanoprost and brimonidine on blood flow velocities of the retrobulbar vessels a 3-month clinical trial. Acta Ophthalmol Scand 2003; 81: 155-160.
58. Erkin EF, Tarhan S, Kaykcioglu OR, Devici H, Guler C, Goktan C. Effects of betaxolol and latanoprost on ocular blood flow and visual field in patients with primary open-angle glaucoma. Eur J Ophthalmol 2004; 14: 211-219.
59. Kaley G, Hintze TH, Panenbeck M, Messina EJ. Role of prostaglandins in microcirculatory function. Adv Prostaglandin Thromboxane Leukot Res 1985; 13: 27-35.
60. Astin M, Stjernschantz J, Selen G. Role of nitric oxide in PGF2 alpha-induced ocular hyperemia. Exp Eye Res 1994; 59: 401-407.
61. Stjernschantz J, Selen G, Astin M, Resul B. Microvascular affects of selective prostaglandin analogues in the eye with special reference to latanoprost and glaucoma treatment. Prog Ret Eye Res 2000; 19 459-496.
62. Michelson G, Schmauss B, Langhans MJ, Harazny J, Groh MJM. Principle, validity, and reliability of scanning laser Doppler flowmetry. J Glaucoma 1996; 5: 99-105.
63. Chauhan BC, Smith FM. Confocal scanning laser Doppler flowmetryexperiments in a model flow system. J Glaucoma 1997; 6 237-245.
64. Bohdanecka Z, Orgul S, Prunte C, Flammmer J. Influence of acquisition parameters on hemodynamic measurements with the Heidelberg Retina Flowmeter at the optic disc. J Glaucoma 1998; 7:151-157.