Compelling EPR evidence that the alternative oxidase is a diiron carboxylate protein

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1777, Issue 4, 2008, Pages 327-330

  Moore, Anthony L ^a   Carré, Jane E ^b   Affourtit, Charles ^c   Albury, Mary S ^a   Crichton, Paul G ^c   Kita, Kiyoshi ^d   Heathcote, Peter ^e  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF TOKYO   (Japan)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Alternative oxidase; Diiron; Electron transfer; Monotopic integral membrane protein; Respiration

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; IRON DERIVATIVE; OXIDOREDUCTASE; PROTEIN DERIVATIVE;

ARTICLE; BACTERIAL MEMBRANE; ELECTRON SPIN RESONANCE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ESCHERICHIA COLI; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY CHAIN; TRYPANOSOMA;

ANIMALS; BINDING SITES; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRON TRANSPORT; IRON; MITOCHONDRIAL MEMBRANES; OXIDOREDUCTASES; TRYPANOSOMA;

ESCHERICHIA COLI; FUNGI;

EID: 40949110571     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2008.01.004     Document Type: Article

References (23)

1. Finnegan P.M., Soole K.L., and Umbach A.L. Alternative mitochondrial electron transport proteins in higher plants. In: Day D.A., Millar A.H., and Whelan J. (Eds). Plant Mitochondria: From Genome to Function (2004), Kluwer Academic Publishers, London 163-20l
2. Berthold D.A., and Stenmark P. Membrane-bound di-iron carboxylate proteins. Annu. Rev. Plant Biol. 54 (2003) 497-517
3. Affourtit C., Albury M.S., Crichton P.G., and Moore A.L. Exploring the molecular nature of alternative oxidase regulation and catalysis. FEBS Lett. 510 (2002) 121-126
4. Moore A.L., Albury M.S., Crichton P.G., and Affourtit C. Function of the alternative oxidase: is it still a scavenger?. Trends Plant Sci. 7 (2002) 478-481
5. McDonald A.E., and Vanlerberghe G.C. Origins, evolutionary history, and taxonomic distribution of alternative oxidase and plastoquinol terminal oxidase. Compar. Biochem. Physiol. 1 (2006) 357-364
6. Chaudhuri M., Ott R.D., and Hill G.C. Trypanosome alternative oxidase: from molecule to function. Trends in Parasit. 22 (2006) 484-491
7. Roberts C.W., Roberts F., Henriquez F.L., Akiyoshi D., Samuel B.U., Richards T.A., Milhous W., Kyle D., McIntosh L., Hill G.C., Chaudhuri M., Tzipori S., and McLeod R. Evidence for mitochondrial-derived alternative oxidase in the apicomplexan parasite Cryptosporidium parvum: a potential anti-microbial agent target. Int. J. Parasitol. 34 (2004) 297-308
8. Suzuki T., Hashimoto T., Yabu Y., Kido Y., Sakamoto K., Nihei C., Hato M., Suzuki S., Amano Y., Nagai K., Hosokawa T., Minagawa N., Ohta N., and Kita K. Direct evidence for cyanide-insensitive quinol oxidase (alternative oxidase) in apicomplexan parasite Cryptosporidium parvum: phylogenetic and therapeutic implications. Biochem. Biophys. Res. Commun. 313 (2004) 1044-1052
9. McDonald A.E., and Vanlerberghe G.C. Branched mitochondrial electron transport in the animalia: presence of alternative oxidase in several animal phyla. IUBMB Life 56 (2004) 333-341
10. Andersson M.E., and Nordlund P. A revised model of the active site of alternative oxidase. FEBS Lett. 449 (1999) 17-22
11. Berthold D.A., Andersson M.E., and Nordlund P. New insight into the structure and function of the alternative oxidase. Biochim. Biophys. Acta 1460 (2000) 241-254
12. Minagawa N., Sakajo S., Komiyama T., and Yoshimoto A. Essential role of ferrous iron in cyanide-resistant respiration in Hansenula anomala. FEBS Lett. 267 (1990) 114-116
13. Ajayi W., Chaudhuri M., and Hill G.C. Site-directed mutagenesis reveals the essentiality of the conserved residues in the putative diiron active site of the trypanosome alternative oxidase. J. Biol. Chem. 277 (2002) 8187-8193
14. Berthold D.A., Voevodskaya N., Stenmark P., Graslund A., and Nordlund P. EPR studies of the mitochondrial alternative oxidase - evidence for a diiron carboxylate center. J. Biol. Chem. 277 (2002) 43608-43614
15. Affourtit C., and Moore A.L. Purification of the plant alternative oxidase from Arum maculatum: measurement, stability and metal requirement. Biochim. Biophys. Acta 1608 (2004) 181-189
16. Rich P.R. Quinol oxidation in Arum maculatum mitochondria and its application to the assay, solubilisation and partial purification of the alternative oxidase. FEBS Lett. 96 (1978) 252-256
17. Berthold D.A., and Siedow J.N. Partial purification of the cyanide-resistant alternative oxidase of skunk cabbage (Symplocarpus foetidus) mitochondria. Plant Physiol. 101 (1993) 113-119
18. Hendrich M.P., Munck E., Fox B.G., and Lipscomb J.D. Integer-spin EPR studies of the fully reduced methane monooxygenase hydroxylase component. J. Am. Chem. Soc. 112 (1990) 5861-5865
19. III] clusters formed in the R2 subunit of ribonucleotide reductase from mouse or Herpes simplex virus: mild chemical reduction of the diferric centres. J. Am. Chem. Soc. 116 (1994) 6429-6430
20. Solomon E.I., Brunold T.C., Davis M.I., Kemsley J.N., Lee S.-K., Lehnert N., Neese F., Skulan A.J., Yang Y.-S., and Zhou J. Geometric and electronic structure/function correlations in non-heme iron enzymes. Chem. Rev. 100 (2000) 235-349
21. Fukai Y., Amino H., Hirawake H., Yabu Y., Ohta N., Minagawa N., Sakajo S., Yoshimoto A., Nagai K., Takamiya S., Kojima S., and Kita K. Functional expression of the ascofuranone-sensitive Trypanosoma brucei brucei alternative oxidase in the cytoplasmic membrane of Escherichia coli. Comp. Biochem. Physiol. 124 (1999) 141-148
22. Fukai Y., Nihei C., Kawai K., Yabu Y., Suzuki T., Ohta N., Minagawa N., Nagai K., and Kita K. Overproduction of highly active trypanosome alternative oxidase in Escherichia coli heme-deficient mutant. Parasitol. Int. 52 (2003) 237-241
23. Woodland M.P., Patil D.S., Cammack R., and Dalton H. ESR studies of protein A of the soluble methane monooxygenase from Methylococcus capsulatus (Bath). Biochim. Biophys. Acta 873 (1986) 237-242