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15
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Odaka, H.5
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Effects of combination treatment with alogliptin (SYR-322), a novel dipeptidyl peptidase-IV inhibitor, and pioglitazone on glycemic control in ob/ob mice
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June 22-26, Chicago, Abst 2151-PO
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Moritoh, Y., Takeuchi, K., Kataoka, O., Asakawa, T., Odaka, H. Effects of combination treatment with alogliptin (SYR-322), a novel dipeptidyl peptidase-IV inhibitor, and pioglitazone on glycemic control in ob/ob mice. 67th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 22-26, Chicago) 2007, Abst 2151-PO.
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Moritoh, Y.1
Takeuchi, K.2
Kataoka, O.3
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Odaka, H.5
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18
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A novel dipeptidyl peptidase-IV inhibitor, alogliptin (SYR-322), is effective in a new rat model of sulfonylurea-induced secondary failure
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June 22-26, Chicago, Abst 2149-PO
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Asakawa, T., Suzuki, N., Moritoh, Y., Kataoka, O., Takeuchi, K., Odaka, H. A novel dipeptidyl peptidase-IV inhibitor, alogliptin (SYR-322), is effective in a new rat model of sulfonylurea-induced secondary failure. 67th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 22-26, Chicago) 2007, Abst 2149-PO.
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Suzuki, N.2
Moritoh, Y.3
Kataoka, O.4
Takeuchi, K.5
Odaka, H.6
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19
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June 9-13, Washington, D.C, Abst 2010-PO
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Takeuchi, K., Moritoh, Y., Asakawa, T., Kataoka, O., Zhang, Z., Odaka, H. Effects of SYR-322, a novel inhibitor of dipeptidyl peptidase-IV, alone or in combination with pioglitazone in obese and non-obese type 2 diabetes model rats and rice. 66th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 9-13, Washington, D.C.) 2006, Abst 2010-PO.
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66th Annu Meet Sci Sess Am Diabetes Assoc (ADA)
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Takeuchi, K.1
Moritoh, Y.2
Asakawa, T.3
Kataoka, O.4
Zhang, Z.5
Odaka, H.6
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20
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40949116810
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Pharmacokinetics, pharmacodynamics, and tolerability of single rising doses of the dipeptidyl peptidase-IV inhibitor alogliptin benzoate (SYR-322) in healthy male subjects
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June 22-26, Chicago, Abst 495-P
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Christopher, R., Covington, P., Davenport, M. et al. Pharmacokinetics, pharmacodynamics, and tolerability of single rising doses of the dipeptidyl peptidase-IV inhibitor alogliptin benzoate (SYR-322) in healthy male subjects. 67th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 22-26, Chicago) 2007, Abst 495-P.
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67th Annu Meet Sci Sess Am Diabetes Assoc (ADA)
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Christopher, R.1
Covington, P.2
Davenport, M.3
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21
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40949106978
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Single-rising-dose pharmacokinetic, pharmacodynamics, and tolerability of alogliptin benzoate (SYR-322), a novel, dipeptidyl peptidase-IV inhibitor, in healthy male subjects
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Sept 17-21, Amsterdam, Abst 0891
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Christopher, R., Covington, P., Davenport, M., Fleck, P., Mekki, Q., Wann, E., Karim, A. Single-rising-dose pharmacokinetic, pharmacodynamics, and tolerability of alogliptin benzoate (SYR-322), a novel, dipeptidyl peptidase-IV inhibitor, in healthy male subjects. 43rd Annu Meet Eur Assoc Study Diabetes (EASD) (Sept 17-21, Amsterdam) 2007, Abst 0891.
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43rd Annu Meet Eur Assoc Study Diabetes (EASD)
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Christopher, R.1
Covington, P.2
Davenport, M.3
Fleck, P.4
Mekki, Q.5
Wann, E.6
Karim, A.7
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22
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42649142880
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Pharmacokinetics, pharmacodynamics, and tolerability of multiple doses of alogliptin benzoate (SYR-322), a dipeptidyl peptidase-IV inhibitor, in patients with type 2 diabetes
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June 22-26, Chicago, Abst 499-P
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Christopher, R., Covington, P., Davenport, M., Fleck, P., Mekki, Q., Wann, E., Karim, A. Pharmacokinetics, pharmacodynamics, and tolerability of multiple doses of alogliptin benzoate (SYR-322), a dipeptidyl peptidase-IV inhibitor, in patients with type 2 diabetes. 67th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 22-26, Chicago) 2007, Abst 499-P.
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Christopher, R.1
Covington, P.2
Davenport, M.3
Fleck, P.4
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Wann, E.6
Karim, A.7
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23
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70549089727
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Single dose pharmacokinetics of alogliptin benzoate (SYR-322), a highly selective dipeptidyl peptidase-4 inhibitor, in subjects with moderate hepatic impairment
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Sept 9-11, San Francisco, Abst 107
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Karim, A., Fleck, P., Dorsey, D., Zhang, W., Mekki, Q., Preston, RA. Single dose pharmacokinetics of alogliptin benzoate (SYR-322), a highly selective dipeptidyl peptidase-4 inhibitor, in subjects with moderate hepatic impairment. 36th Annu Meet Am Coll Clin Pharmacol (ACCP) (Sept 9-11, San Francisco) 2007, Abst 107.
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36th Annu Meet Am Coll Clin Pharmacol (ACCP)
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Karim, A.1
Fleck, P.2
Dorsey, D.3
Zhang, W.4
Mekki, Q.5
Preston, R.A.6
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A study to evaluate SYR-322 25 plus pioglitazone HCl (ACTOS®) for the treatment of subjects with inadequately controlled type 2 diabetes (NCT00432276). ClinicalTrials.gov Web site, January 9, 2008.
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32
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A study to evaluate SYR-322 plus pioglitazone HCl (Actos®), SYR-322 alone, or pioglitazone alone for the treatment of type 2 diabetes (NCT00395512). ClinicalTrials.gov Web site, January 9, 2008.
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No pharmacokinetic interaction between alogliptin benzoate (SYR-322) and pioglitazone hydrochloride
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June 22-26, Chicago, Abst 2117-PO
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Karim, A., Fleck, P., Joseph, M., Laurent, A., Munsaka, M., Wann, E., Mekki, Q. No pharmacokinetic interaction between alogliptin benzoate (SYR-322) and pioglitazone hydrochloride. 67th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 22-26, Chicago) 2007, Abst 2117-PO.
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67th Annu Meet Sci Sess Am Diabetes Assoc (ADA)
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Karim, A.1
Fleck, P.2
Joseph, M.3
Laurent, A.4
Munsaka, M.5
Wann, E.6
Mekki, Q.7
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35
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67649320615
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Lack of effect of multiple doses of alogliptin benzoate (SYR-322) on the pharmacokinetics of glyburide in healthy subjects
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June 22-26, Chicago, Abst 2135-PO
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Fleck, P., Karim, A., Harris, S., Moore, R., Munsaka, M., Wann, E., Mekki, Q. Lack of effect of multiple doses of alogliptin benzoate (SYR-322) on the pharmacokinetics of glyburide in healthy subjects. 67th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 22-26, Chicago) 2007, Abst 2135-PO.
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(2007)
67th Annu Meet Sci Sess Am Diabetes Assoc (ADA)
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Fleck, P.1
Karim, A.2
Harris, S.3
Moore, R.4
Munsaka, M.5
Wann, E.6
Mekki, Q.7
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36
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41649085328
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Lack of pharmacokinetic interaction between alogliptin benzoate (SYR-322) and metformin in healthy subjects
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June 22-26, Chicago, Abst 2136-PO
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Covington, P., Christopher, R., Davenport, M., Fleck, P., Mekki, Q., Wann, E., Karim, A. Lack of pharmacokinetic interaction between alogliptin benzoate (SYR-322) and metformin in healthy subjects. 67th Annu Meet Sci Sess Am Diabetes Assoc (ADA) (June 22-26, Chicago) 2007, Abst 2136-PO.
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(2007)
67th Annu Meet Sci Sess Am Diabetes Assoc (ADA)
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Covington, P.1
Christopher, R.2
Davenport, M.3
Fleck, P.4
Mekki, Q.5
Wann, E.6
Karim, A.7
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37
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40949126208
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Assessment of drug interaction between alogliptin benzoate (SYR-322): A highly selective dipeptidyl peptidase-1 inhibitor, and warfarin at steady state
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Sept 9-11, San Francisco, Abst 106
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Karim, A., Harris, S., Fleck, P., Moore, R., Zhang, W., Mekki, Q. Assessment of drug interaction between alogliptin benzoate (SYR-322): A highly selective dipeptidyl peptidase-1 inhibitor, and warfarin at steady state. 36th Annu Meet Am Coll Clin Pharmacol (ACCP) (Sept 9-11, San Francisco) 2007, Abst 106.
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(2007)
36th Annu Meet Am Coll Clin Pharmacol (ACCP)
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Karim, A.1
Harris, S.2
Fleck, P.3
Moore, R.4
Zhang, W.5
Mekki, Q.6
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