Commercially Available Gas-Permeable Cell Culture Bags May Not Prevent Anoxia in Cultured or Shipped Islets

Transplantation Proceedings

Volumn 40, Issue 2, 2008, Pages 395-400

  Avgoustiniatos, E S ^a   Hering, B J ^a   Rozak, P R ^a   Wilson, J R ^b   Tempelman, L A ^c   Balamurugan, A N ^a   Welch, D P ^b   Weegman, B P ^a   Suszynski, T M ^a   Papas, K K ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b Wilson Wolf Manufacturing Corporation   (United States)

^c Giner Incorporated and Giner Electrochemical Systems LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SILASTIC;

ARTICLE; CELL CULTURE; CELL DENSITY; CELL HYPOXIA; CELL SIZE; CELL VOLUME; CONTAMINATION; DEVICE; GAS PERMEABILITY; HUMAN; MEMBRANE PERMEABILITY; OXYGEN DIFFUSION; OXYGENATION; PANCREAS ISLET CELL; PRIORITY JOURNAL; SHIPPING; TEMPERATURE; THICKNESS;

ANOXIA; CELL CULTURE TECHNIQUES; CELL HYPOXIA; DIFFUSION; EQUIPMENT DESIGN; HUMANS; ISLETS OF LANGERHANS; ORGAN PRESERVATION; OXYGEN; OXYGEN CONSUMPTION; SOLUBILITY;

EID: 40949093600     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.01.059     Document Type: Article

References (18)

1. Jijakli H., Rasschaert J., Nadi A.B., et al. Relevance of lactate dehydrogenase activity to the control of oxidative glycolysis in pancreatic islet β-cells. Arch Biochem Biophys 327 (1996) 260
2. Papas K.K., Colton C.K., Gounarides J.S., et al. NMR spectroscopy in β cell engineering and islet transplantation. Ann NY Acad Sci 944 (2001) 96
3. Ichii H., Inverardi L., Pileggi A., et al. A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations. Am J Transplant 5 (2005) 1635
4. Papas K.K., Bauer A.C., Avgoustiniatos E.S., et al. Vitamin E homologs protect cultured islets from anoxia-induced death: implications in islet processing and engraftment. Diabetologia 48 Suppl 1 (2005) A185
5. Papas K.K., Avgoustiniatos E.S., Tempelman L.A., et al. High-density culture of human islets on top of silicone rubber membranes. Transplant Proc 37 (2005) 3412
6. Olsson R., and Carlsson P.-O. Oxygenation of cultured pancreatic islets. Adv Exp Med Biol 578 (2006) 263
7. Papas K.K., Hering B.J., Rozak P.R., et al. Improved islet culture on top of gas-permeable membranes. Am J Transplant 7 Suppl 2 (2007) 568
8. Avgoustiniatos E.S., Hering B.J., Rozak P.R., et al. Islet culture at high surface densities on top of silicone rubber membranes compares favorably to standard culture. Xenotransplantation 14 (2007) 489
9. Ma N., Chalmers J.J., Aunins J.G., et al. Quantitative studies of cell-bubble interactions and cell damage at different pluronic F-68 and cell concentrations. Biotechnol Prog 20 (2004) 1183
10. Avgoustiniatos E.S., and Colton C.K. Design considerations in immunoisolation. In: Lanza R.P., Langer R., and Chick W.L. (Eds). Principles of tissue engineering (1997), RG Landes, Austin, Tex 333
11. Avgoustiniatos E.S. Oxygen diffusion limitations in pancreatic islet culture and immunoisolation (2002), PhD Thesis, Massachusetts Institute of Technology, Cambridge, Mass
12. Fraker C.A., Álvarez S., Papadopoulos P., et al. Enhanced oxygenation promotes beta cell differentiation in vitro. Stem Cells (2007) [Epub ahead of print]
13. Avgoustiniatos E.S., and Colton C.K. Effect of external oxygen mass transfer resistances on viability of immunoisolated tissue. Ann N Y Acad Sci 831 (1997) 145
14. Avgoustiniatos E.S., Dionne K.E., Wilson D.F., et al. Measurements of the effective diffusion coefficient of oxygen in pancreatic islets. Ind Eng Chem Res 46 (2007) 6157
15. Teflon FEP Film. DuPont Bulletin E-80412.
16. Ichii H., Sakuma Y., Pileggi A., et al. Shipment of human islets for transplantation. Am J Transplant 7 (2007) 1010
17. Papas K.K., Avgoustiniatos E.S., Rozak P.R., et al. Seven-day culture enhances potency and reduces immunogenicity of porcine islets. Xenotransplantation 14 (2007) 420
18. Rozak P.R., Avgoustiniatos E.S., Weegman B.P., et al. Phase change material maintains temperature control in an islet shipping container. Xenotransplantation 14 (2007) 489