Long-Term Survival and Function of Intraportal Porcine and Human Islet Xenografts in Nondiabetic Nude Mice

Transplantation Proceedings

Volumn 40, Issue 2, 2008, Pages 584-586

  Xu, B Y ^a   Yu, Y ^a   Al Abdullah, I H ^b   Kandeel, F ^b   Hering, B ^c   Wright Jr , J R ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CORRELATION ANALYSIS; GRAFT SURVIVAL; HUMAN; HUMAN TISSUE; INFLAMMATION; INSULIN BLOOD LEVEL; LIVER HISTOLOGY; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS DUCT; PANCREAS FUNCTION; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SURVIVAL TIME; SWINE; TILAPIA; TOXICITY; TRANSPLANTATION TOLERANCE; XENOGRAFT;

ANIMALS; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, NUDE; PORTAL SYSTEM; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 40949089019     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.02.002     Document Type: Article

References (4)

1. Goto M., Groth C., Nilsson B., et al. Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction. Xenotransplantation 11 (2004) 195
2. Al-Jazaeri A., Xu B.-Y., Yang H., et al. Effect of glucose toxicity on intraportal tilapia islet xenotransplantation in nude mice. Xenotransplantation 12 (2005) 189
3. Bennet W., Sundberg B., Groth C., et al. Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?. Diabetes 48 (1999) 1907
4. Bennet W., Sundberg B., Lundgren T., et al. Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin. Transplantation 69 (2000) 711