The effect of three-dimensional matrix-embedding of endothelial cells on the humoral and cellular immune response

Seminars in Immunology

Volumn 20, Issue 2, 2008, Pages 117-122

  Methe, Heiko ^a,b   Hess, Shmuel ^a,c   Edelman, Elazer R ^a,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Endothelial cells; Extracellular matrix; Immunity; Tissue engineering

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ADAPTIVE IMMUNITY; ARTERY INTIMA PROLIFERATION; BLOOD VESSEL INJURY; CELLULAR IMMUNITY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOGENICITY; IMMUNOLOGICAL MEMORY; IMMUNOREACTIVITY; IMMUNOSTIMULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; REVIEW; THROMBOSIS; TISSUE ENGINEERING;

ANIMALS; ANTIBODY FORMATION; CELL MOVEMENT; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; HUMANS; IMMUNITY, CELLULAR; IMMUNOLOGIC FACTORS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTE ACTIVATION; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 40849137622     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2007.12.005     Document Type: Review

References (55)

1. Luscher T.F., and Barton M. Biology of the endothelium. Clin Cardiol 20 November (11 Suppl. 2) (1997) II-3-II-10
2. Ross R. Atherosclerosis-an inflammatory disease. New Engl J Med 340 January (2) (1999) 115-126
3. Schwartz R.S. Pathophysiology of restenosis: interaction of thrombosis, hyperplasia, and/or remodeling. Am J Cardiol 81 April (7A) (1998) 7E-14E
4. Middleton J., Americh L., Gayon R., Julien D., Aguilar L., Amalric F., et al. Endothelial cell phenotypes in the rheumatoid synovium: activated, angiogenic, apoptotic and leaky. Arthritis Res Ther 6 2 (2004) 60-72
5. Szekanecz Z., and Koch A.E. Vascular endothelium and immune responses: implications for inflammation and angiogenesis. Rheum Dis Clin N Am 30 February (1) (2004) 97-114
6. Lowe P.M., Lee M.L., Jackson C.J., To S.S., Cooper A.J., and Schrieber L. The endothelium in psoriasis. Br J Dermatol 132 April (4) (1995) 497-505
7. Andjelkovic A.V., and Pachter J.S. Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease. J Neurosci Res 51 February (4) (1998) 423-430
8. Hatoum O.A., Binion D.G., Otterson M.F., and Gutterman D.D. Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation. Gastroenterology 125 July (1) (2003) 58-69
9. Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. New Engl J Med 352 April (16) (2005) 1685-1695
10. Danese S., Dejana E., and Fiocchi C. Immune regulation by microvascular endothelial cells: directing innate and adaptive immunity, coagulation, and inflammation. J Immunol 178 May (10) (2007) 6017-6022
11. Edfeldt K., Swedenborg J., Hansson G.K., and Yan Z.Q. Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation 105 March (10) (2002) 1158-1161
12. Methe H., Zimmer E., Grimm C., Nabauer M., and Koglin J. Evidence for a role of toll-like receptor 4 in development of chronic allograft rejection after cardiac transplantation. Transplantation 78 November (9) (2004) 1324-1331
13. Dunzendorfer S., Lee H.K., Soldau K., and Tobias P.S. Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses. FASEB J 18 July (10) (2004) 1117-1119
14. Heidemann J., Domschke W., Kucharzik T., and Maaser C. Intestinal microvascular endothelium and innate immunity in inflammatory bowel disease: a second line of defense?. Infect Immun 74 October (10) (2006) 5425-5432
15. Faure E., Thomas L., Xu H., Medvedev A., Equils O., and Arditi M. Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation. J Immunol 166 February (3) (2001) 2018-2024
16. Tissari J., Siren J., Meri S., Julkunen I., and Matikainen S. IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. J Immunol 174 April (7) (2005) 4289-4294
17. Zeuke S., Ulmer A.J., Kusumoto S., Katus H.A., and Heine H. TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS. Cardiovasc Res 56 October (1) (2002) 126-134
18. Marelli-Berg F.M., and Jarmin S.J. Antigen presentation by the endothelium: a green light for antigen-specific T cell trafficking?. Immunol Lett 93 May (2-3) (2004) 109-113
19. Matzinger P. Friendly and dangerous signals: is the tissue in control?. Nat Immunol 8 January (1) (2007) 11-13
20. Weaver V.M., Petersen O.W., Wang F., Larabell C.A., Briand P., Damsky C., et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 137 April (1) (1997) 231-245
21. Lukashev M.E., and Werb Z. ECM signalling: orchestrating cell behaviour and misbehaviour. Trends Cell Biol 8 November (11) (1998) 437-441
22. Sasaki T., Takagi M., Soma T., and Yoshida T. 3D culture of murine hematopoietic cells with spatial development of stromal cells in nonwoven fabrics. Cytotherapy 4 3 (2002) 285-291
23. Edelman D.B., and Keefer E.W. A cultural renaissance: in vitro cell biology embraces three-dimensional context. Exp Neurol 192 March (1) (2005) 1-6
24. Griffith L.G., and Swartz M.A. Capturing complex 3D tissue physiology in vitro. Nat Rev 7 March (3) (2006) 211-224
25. Knight B., Laukaitis C., Akhtar N., Hotchin N.A., Edlund M., and Horwitz A.R. Visualizing muscle cell migration in situ. Curr Biol 10 May (10) (2000) 576-585
26. Roskelley C.D., Desprez P.Y., and Bissell M.J. Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc Natl Acad Sci USA 91 December (26) (1994) 12378-12382
27. Centra M., Ratych R.E., Cao G.L., Li J., Williams E., Taylor R.M., et al. Culture of bovine pulmonary artery endothelial cells on Gelfoam blocks. FASEB J 6 September (12) (1992) 3117-3121
28. Nathan A., Nugent M.A., and Edelman E.R. Tissue engineered perivascular endothelial cell implants regulate vascular injury. Proc Natl Acad Sci USA 92 August (18) (1995) 8130-8134
29. Nugent H.M., and Edelman E.R. Endothelial implants provide long-term control of vascular repair in a porcine model of arterial injury. J Surg Res 99 August (2) (2001) 228-234
30. Nugent H.M., Groothuis A., Seifert P., Guerraro J.L., Nedelman M., Mohanakumar T., et al. Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. J Vasc Res 39 November-December (6) (2002) 524-533
31. Nugent H.M., Rogers C., and Edelman E.R. Endothelial implants inhibit intimal hyperplasia after porcine angioplasty. Circ Res 84 March (4) (1999) 384-391
32. Methe H., Nugent H.M., Groothuis A., Seifert P., Sayegh M.H., and Edelman E.R. Matrix embedding alters the immune response against endothelial cells in vitro and in vivo. Circulation 112 August (9 Suppl.) (2005) I89-I95
33. Stupack D.G., and Cheresh D.A. ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands. Sci STKE 2002 February (119) (2002) PE7
34. Wheatley E.M., McKeown-Longo P.J., Vincent P.A., and Saba T.M. Incorporation of fibronectin into matrix decreases TNF-induced increase in endothelial monolayer permeability. Am J Physiol 265 August (2 Pt 1) (1993) L148-L157
35. Mocsai A., Abram C.L., Jakus Z., Hu Y., Lanier L.L., and Lowell C.A. Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs. Nat Immunol 7 December (12) (2006) 1326-1333
36. Davies P.F. Flow-mediated endothelial mechanotransduction. Physiol Rev 75 July (3) (1995) 519-560
37. Orr A.W., Ginsberg M.H., Shattil S.J., Deckmyn H., and Schwartz M.A. Matrix-specific suppression of integrin activation in shear stress signaling. Mol Biol Cell 17 November (11) (2006) 4686-4697
38. Orr A.W., Sanders J.M., Bevard M., Coleman E., Sarembock I.J., and Schwartz M.A. The subendothelial extracellular matrix modulates NF-kappaB activation by flow: a potential role in atherosclerosis. J Cell Biol 169 April (1) (2005) 191-202
39. Pauli B.U., and Lee C.L. Organ preference of metastasis. The role of organ-specifically modulated endothelial cells. Laboratory investigation. J Tech Methods Pathol 58 April (4) (1988) 379-387
40. Aird W.C. Phenotypic heterogeneity of the endothelium. I: Structure, function, and mechanisms. Circ Res 100 February (2) (2007) 158-173
41. Hoshiga M., Alpers C.E., Smith L.L., Giachelli C.M., and Schwartz S.M. Alpha-v beta-3 integrin expression in normal and atherosclerotic artery. Circ Res 77 December (6) (1995) 1129-1135
42. Methe H., and Edelman E.R. Tissue engineering of endothelial cells and the immune response. Transplant Proc 38 December (10) (2006) 3293-3299
43. Kern A., Liu K., and Mansbridge J. Modification of fibroblast gamma-interferon responses by extracellular matrix. J Invest Dermatol 117 July (1) (2001) 112-118
44. Stegemann J.P., and Nerem R.M. Altered response of vascular smooth muscle cells to exogenous biochemical stimulation in two- and three-dimensional culture. Exp Cell Res 283 February (2) (2003) 146-155
45. Mohtashami M., and Zuniga-Pflucker J.C. Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development. J Immunol 176 January (2) (2006) 730-734
46. Methe H., and Edelman E.R. Cell-matrix contact prevents recognition and damage of endothelial cells in states of heightened immunity. Circulation 114 July (1 Suppl.) (2006) I233-I238
47. Bobryshev Y.V. Dendritic cells in atherosclerosis: current status of the problem and clinical relevance. Eur Heart J 26 September (17) (2005) 1700-1704
48. Schlichting C.L., Schareck W.D., and Weis M. Dendritic cell endothelium interaction in autoimmunity. Curr Pharm Des 10 2 (2004) 171-181
49. Weis M., Schlichting C.L., Engleman E.G., and Cooke J.P. Endothelial determinants of dendritic cell adhesion and migration: new implications for vascular diseases. Arterioscler Thromb Vasc Biol 22 November (11) (2002) 1817-1823
50. Methe H., Hess S., and Edelman E.R. Endothelial cell-matrix interactions determine maturation of dendritic cells. Eur J Immunol 37 July (7) (2007) 1773-1784
51. Lan Y.Y., Wang Z., Raimondi G., Wu W., Colvin B.L., de Creus A., et al. Alternatively activated" dendritic cells preferentially secrete IL-10, expand Foxp3+CD4+ T cells, and induce long-term organ allograft survival in combination with CTLA4-Ig. J Immunol 177 November (9) (2006) 5868-5877
52. Morelli A.E., and Thomson A.W. Tolerogenic dendritic cells and the quest for transplant tolerance. Nat Rev Immunol 7 (2007) 610-621
53. Methe H., Groothuis A., Sayegh M.H., and Edelman E.R. Matrix adherence of endothelial cells attenuates immune reactivity: induction of hyporesponsiveness in allo- and xenogeneic models. FASEB J 21 May (7) (2007) 1515-1526
54. Ruegg C., and Mariotti A. Vascular integrins: pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis. Cell Mol Life Sci 60 June (6) (2003) 1135-1157
55. Hehlgans S., Haase M., and Cordes N. Signalling via integrins: implications for cell survival and anticancer strategies. Biochim Biophys Acta 1775 January (1) (2007) 163-180