Effect of acute lindane and alcohol intoxication on serum concentration of enzymes and fatty acids in rats

Food and Chemical Toxicology

Volumn 46, Issue 5, 2008, Pages 1739-1743

  Radosavljevic T ^a   Mladenovic D ^a   Vucevic D ^a   Petrovic J ^a   Hrncic D ^a   Djuric, D ^a   Loncar Stevanovic H ^a   Stanojlovic O ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Ethanol; Fatty acids; Lindane; Liver injury; Rats

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; FATTY ACID; GAMMA GLUTAMYLTRANSFERASE; LACTATE DEHYDROGENASE; LINDANE; LINOLEIC ACID; LIVER ENZYME; PALMITIC ACID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL INTOXICATION; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FATTY ACID BLOOD LEVEL; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER INJURY; MALE; NONHUMAN; RAT;

ALCOHOLIC INTOXICATION; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; FATTY ACIDS; INSECTICIDES; LINDANE; LIVER; MALE; RATS; RATS, WISTAR;

RATTUS; RATTUS NORVEGICUS;

EID: 40849119669     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.01.011     Document Type: Article

References (24)

1. Boll M., Weber L.W., and Stampfl A. The effect of gamma-hexachlorocyclohexane (lindane) on the activities of liver lipogenic enzymes and on serum lipids in rats. Z. Naturforsch. [C] 50 (1995) 135-142
2. Boll M., Weber L.W., and Stampfl A. The response of rat serum lipids to diets of varying composition or contaminated with organochlorine pesticides. Z. Naturforsch. [C] 51 (1996) 91-100
3. Caballeria J. Current concepts in alcohol metabolism. Ann. Hepatol. 2 (2003) 60-68
4. Cohen J.A., and Kaplan M.M. The SGOT/SGPT ratio -- an indicator of alcoholic liver disease. Dig. Dis. Sci. 24 (1979) 835-838
5. Gutierrez A.M., Reboredo G.R., Arcemis C.J., and Catala A. The effect of lindane on the lipid peroxidation of microsomes and mitochondria isolated from liver and heart of Columba livia. Pest. Biochem. Physiol. 68 (2000) 119-126
6. Hoyer A., Grandjean P., Jorgensen T., Brock J.W., and Hartvig H.B. Organochlorine exposure and risk of breast cancer. Lancet 352 (1998) 1816-1820
7. Joy R., and Albertson T. Lindane and limbic system excitability. Neurotoxicology 6 (1985) 193-214
8. Joy R. Mode of action of lindane, dieldrin, and related insecticides in the central nervous system. Neurobehav. Toxicol. Teratol. 4 (1982) 813-823
9. Joy R.M., Stark L.G., and Albertson T.E. Proconvulsant effects of lindane: enhancement of amygdaloid kindling in the rat. Neurobehav. Toxicol. Teratol. 4 (1982) 347-354
10. Kashyap S.K., Nigam S.K., Gupta R.C., Karnik A.B., and Chatterjee S.K. Carcinogenicity of hexachlorocyclohexane (BHC) in pure inbred Swiss mice. J. Environ. Sci. Health B 14 (1979) 305-318
11. Kashyap S.K. Health surveillance and biological monitoring of pesticide formulators in India. Toxicol. Lett. 33 (1986) 107-114
12. Kutz F.W., Wood P.H., and Bottimore D.P. Organochlorine pesticides and polychlorinated biphenyls in human adipose tissue. Rev. Environ. Contam. Toxicol. 120 (1991) 1-82
13. Li Y.M., Chen S.H., Yu C.H., Zhang Y., and Xu G.Y. Effect of acute alcoholism on hepatic enzymes and oxidation/antioxidation in rats. Hepatobiliary Pancreat. Dis. Int. 3 (2004) 241-244
14. Lieber C.S. Hepatic metabolism and toxic effects of ethanol: 1991 up-date. Alcohol Clin. Exp. Res. 15 (1991) 573-592
15. Mladenović D., Hrnčić D., Vučević D., Radosavljević T., Lončar-Stevanović H., Petrović J., Šušić V., Djuric D., and Stanojlović O. Ethanol suppressed seizures in lindane-treated rats. Electroencephalographic and behavioral studies. J. Physiol. Pharmacol. 58 (2007) 641-656
16. Parmar D., Yadav S., Dayal M., Johri A., Dhawan A., and Seth P.K. Effect of lindane on hepatic and brain cytochrome P450s and influence of P450 modulation in lindane-induced neurotoxicity. Food Chem. Toxicol. 41 (2003) 1077-1087
17. Prabhakaran S., and Devi K.S. Impact of protein deficiency and exposure to hexachlorocyclohexane or malathion on lipid metabolism in pregnant rats. Indian J. Biochem. Biophys. 30 (1993) 234-238
18. Ravinder P., Srinivasan K., and Radhakrishnamurty R. Dietary hexachlorocyclohexane induced changes in blood and liver lipids in albino mice. Indian J. Exp. Biol. 28 (1990) 155-157
19. Renner E.L., and Dalenbach A. Increased liver enzymes: what should be done?. Ther. Umsch. 49 (1992) 281-286
20. Schulteis G., and Liu J. Brain reward deficits accompany withdrawal (hangover) from acute ethanol in rats. Alcohol 39 (2006) 21-28
21. Srinivasan K., and Radhakrishnamurty R. Biochemical changes produced by β- and γ-hexachlorocyclohexane isomers in albino rats. J. Environ. Sci. Health 23 (1988) 367-386
22. Videla L.A., Simizu K., Barros S.B.M., and Junqueira V.B.C. Mechanisms of lindane-induced hepatotoxicity: alterations of the respiratory activity and sinusoidal glutathione efflux in the isolated perfused rat liver. Xenobiotica 21 (1991) 1023-1032
23. Wang F., Xu Z.R., and Su J.H. Effect of HCH Contamination of diet on the growth performance and immune and antioxidant ability in growing/finishing pigs. Vet. Res. Commun. 30 (2006) 645-654
24. Yue M., Ni Q., Yu C.H., Ren K.M., Chen W.X., and Li Y.M. Transient elevation of hepatic enzymes in volunteers after intake of alcohol. Hepatobiliary Pancreat. Dis. Int. 5 (2006) 52-55