Reimplantation of the ureter after unilateral ureteral obstruction provides a model that allows functional evaluation

Kidney International

Volumn 73, Issue 7, 2008, Pages 885-889

  Tapmeier, T T ^a   Brown, K L ^a   Tang, Z ^a,b   Sacks, S H ^a   Sheerin, N S ^c   Wong, W ^a,d  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d GUY S HOSPITAL   (United Kingdom)

Author keywords

Inflammation; Reimplantation; Renal fibrosis; UUO

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; EVALUATION; FEMALE; FUNCTIONAL ASSESSMENT; INFLAMMATION; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY INJURY; LIVER FIBROSIS; LONGITUDINAL STUDY; MACROPHAGE; MEASUREMENT; MOUSE; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN URINE LEVEL; REIMPLANTATION; T LYMPHOCYTE; UREA NITROGEN BLOOD LEVEL; URETER OBSTRUCTION;

EID: 40849118171     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002797     Document Type: Article

References (11)

1. Harris RC, Neilson EG. Toward a unified theory of renal progression. Annu Rev Med 2006; 57: 365-380.
2. Klahr S, Morrissey J. Obstructive nephropathy and renal fibrosis. Am J Physiol Renal Physiol 2002; 283: F861-F875.
3. Thornhill BA, Forbes MS, Marcinko ES et al. Glomerulotubular disconnection in neonatal mice after relief of partial ureteral obstruction. Kidney Int 2007; 72: 1103-1112.
4. Cochrane AL, Kett MM, Samuel CS et al. Renal structural and functional repair in a mouse model of reversal of ureteral obstruction. J Am Soc Nephrol 2005; 16: 3623-3630.
5. Chevalier RL, Kim A, Thornhill BA et al. Recovery following relief of unilateral ureteral obstruction in the neonatal rat. Kidney Int 1999; 55: 793-807.
6. Chevalier RL, Thornhill BA, Chang AY. Unilateral ureteral obstruction in neonatal rats leads to renal insufficiency in adulthood. Kidney Int 2000; 58: 1987-1995.
7. Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med 1998; 339: 1448-1456.
8. Kaneto H, Morrissey J, Klahr S. Increased expression of TGF-beta 1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation. Kidney Int 1993; 44: 313-321.
9. Robson MG, Cook HT, Botto M et al. Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice. J Immunol 2001; 166: 6820-6828.
10. Vielhauer V, Berning E, Eis V et al. CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome. Kidney Int 2004; 66: 2264-2278.
11. Brown K, Moxham V, Karegli J et al. Ultra-localization of Foxp3+ T cells within renal allografts shows infiltration of tubules mimicking rejection. Am J Pathol 2007; 171: 1915-1922.