A new approach for drug discovery from glycobiology and phage-displayed peptide library technology

Biochimica et Biophysica Acta - General Subjects

Volumn 1780, Issue 3, 2008, Pages 497-503

  Taki, Takao ^a   Ishikawa, Dai ^a   Ogino, Koichi ^a   Tanaka, Michinori ^a   Oku, Naoto ^b   Asai, Tomohiro ^b   Popa, Iuliana ^c,d   Portoukalian, Jacques ^c  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c UNIVERSITÉ LYON 1   (France)

^d PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

Author keywords

Angiogenesis; Drug discovery; Ganglioside; Glyco replica peptide; Glycobiology; Glycolipid; Melanoma; Metastasis; Molecular mimicry; Phage displayed peptide library

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; GANGLIOSIDE GD 1A; GANGLIOSIDE GD3; GLYCOSPHINGOLIPID; MONOCLONAL ANTIBODY; PEPTIDE; PEPTIDE LIBRARY;

ADHESION; AMINO ACID SEQUENCE; ANGIOGENESIS; ANTIBODY PRODUCTION; BINDING AFFINITY; BIOPANNING; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; GLYCOBIOLOGY; HEAVY CHAIN; HUMAN; IMMUNE RESPONSE; LIGHT CHAIN; LIVER; LIVER SINUSOID; LUNG; LYMPHOSARCOMA; MELANOMA; METASTASIS; MOLECULAR RECOGNITION; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; REVIEW; THIN LAYER CHROMATOGRAPHY; TUMOR CELL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CELL ADHESION; DRUG DESIGN; G(M1) GANGLIOSIDE; GANGLIOSIDES; GLYCOMICS; GLYCOSPHINGOLIPIDS; HUMANS; MELANOMA; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDE LIBRARY; PEPTIDES;

MUS;

EID: 40849106336     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2008.01.005     Document Type: Review

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