The cost of community-managed viral respiratory illnesses in a cohort of healthy preschool-aged children

Respiratory Research

Volumn 9, Issue , 2008, Pages

  Lambert, Stephen B ^a,b   Allen, Kelly M ^a,c   Carter, Robert C ^a,d   Nolan, Terence M ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d DEAKIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMBULATORY CARE; ARTICLE; AUSTRALIA; COHORT ANALYSIS; COMPARATIVE STUDY; COST OF ILLNESS; ECONOMICS; FEMALE; HEALTH CARE COST; HUMAN; INFANT; INFLUENZA; MALE; MEDICAL RECORD; PRESCHOOL CHILD; RESPIRATORY TRACT INFECTION; SELF CARE; VIROLOGY; VIRUS INFECTION;

AMBULATORY CARE; AUSTRALIA; CHILD, PRESCHOOL; COHORT STUDIES; COST OF ILLNESS; FEMALE; HEALTH CARE COSTS; HUMANS; INFANT; INFLUENZA, HUMAN; MALE; MEDICAL RECORDS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY TRACT INFECTIONS; SELF CARE; VIRUS DISEASES;

EID: 40849105660     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-9-11     Document Type: Article

References (66)

1. Fendrick AM, Monto AS, Nightengale B, Sarnes M. The economic burden of non-influenza-related viral respiratory tract infection in the United States. Arch Intern Med 2003, 163:487-494. 10.1001/archinte.163.4.487, 12588210.
2. Principi N, Esposito S, Marchisio P, Gasparini R, Crovari P. Socioeconomic impact of influenza on healthy children and their families. Pediatr Infect Dis J 2003, 22:S207-210.
3. Principi N, Esposito S, Gasparini R, Marchisio P, Crovari P. Burden of influenza in healthy children and their households. Arch Dis Child 2004, 89:1002-1007. 10.1136/adc.2003.045401, 15499051.
4. Esposito S, Gasparini R, Bosis S, Marchisio P, Tagliabue C, Tosi S, Bianchi C, Crovari P, Principi N. Clinical and socio-economic impact of influenza and respiratory syncytial virus infection on healthy children and their households. Clin Microbiol Infect 2005, 11:933-936. 10.1111/j.1469-0691.2005.01270.x, 16216113.
5. Esposito S, Marchisio P, Bosis S, Lambertini L, Claut L, Faelli N, Bianchi C, Colombo GL, Principi N. Clinical and economic impact of influenza vaccination on healthy children aged 2-5 years. Vaccine 2006, 24:629-635. 10.1016/j.vaccine.2006.03.059, 16157429.
6. Cohen GM, Nettleman MD. Economic impact of influenza vaccination in preschool children. Pediatrics 2000, 106:973-976. 10.1542/peds.106.5.973, 11061762.
7. Weycker D, Edelsberg J, Halloran ME, Longini IM, Nizam A, Ciuryla V, Oster G. Population-wide benefits of routine vaccination of children against influenza. Vaccine 2005, 23:1284-1293. 10.1016/j.vaccine.2004.08.044, 15652671.
8. Skowronski DM, Woolcott JC, Tweed SA, Brunham RC, Marra F. Potential cost-effectiveness of annual influenza immunization for infants and toddlers: experience from Canada. Vaccine 2006, 24:4222-4232. 10.1016/j.vaccine.2005.12.036, 16423432.
9. Marchetti M, Kuhnel UM, Colombo GL, Esposito S, Principi N. Cost-effectiveness of adjuvanted influenza vaccination of healthy children 6 to 60 months of age. Hum Vaccin 2007, 3:14-22.
10. Fedson DS, Nichol KL. Influenza vaccination: policy versus evidence: no gap between policy and evidence. BMJ 2006, 333:1020. 1635630, 17095789, 10.1136/bmj.39024.451389.FA.
11. Coleman MS, Washington ML, Orenstein WA, Gazmararian JA, Prill MM. Interdisciplinary epidemiologic and economic research needed to support a universal childhood influenza vaccination policy. Epidemiol Rev 2006, 28:41-46. 10.1093/epirev/mxj008, 16740584.
12. Kaiser J. A one-size-fits-all flu vaccine?. Science 2006, 312:380-382. 10.1126/science.312.5772.380, 16627732.
13. Hall CB. Respiratory syncytial virus and parainfluenza virus. N Engl J Med 2001, 344:1917-1928. 10.1056/NEJM200106213442507, 11419430.
14. Bitko V, Musiyenko A, Shulyayeva O, Barik S. Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 2005, 11:50-55. 10.1038/nm1164, 15619632.
15. World Health Organization Writing Group Nonpharmaceutical interventions for pandemic influenza, international measures. Emerg Infect Dis 2006, 12:81-87. World Health Organization Writing Group.
16. World Health Organization Writing Group Nonpharmaceutical interventions for pandemic influenza, national and community measures. Emerg Infect Dis 2006, 12:88-94. World Health Organization Writing Group.
17. Lo JY, Tsang TH, Leung YH, Yeung EY, Wu T, Lim WW. Respiratory infections during SARS outbreak, Hong Kong, 2003. Emerg Infect Dis 2005, 11:1738-1741.
18. Markel H, Lipman HB, Navarro JA, Sloan A, Michalsen JR, Stern AM, Cetron MS. Nonpharmaceutical interventions implemented by US cities during the 1918-1919 influenza pandemic. JAMA 2007, 298:644-654. 10.1001/jama.298.6.644, 17684187.
19. Lambert S, Allen K, Druce J, Birch C, Mackay I, Carlin J, Carapetis J, Sloots T, Nissen M, Nolan T. Community epidemiology of human metapneumovirus, human coronavirus NL63, and other respiratory viruses in healthy pre-school aged children using parent-collected specimens. Pediatrics 2007, 120:e929-e937. 10.1542/peds.2006-3703, 17875651.
20. O'Grady K, O'Sullivan J, Gabriel S, Lambert S, Kefford M, Nolan T. Child and adolescent vaccine studies in Melbourne. Victorian Infectious Diseases Bulletin 2004, 7:33-36.
21. Australian Bureau of Statistics: Household Income and Income Distribution, Australia, 2003-04. Volume 6523.0. , http://www.abs.gov.au/AUSSTATS/abs@.nsf/DetailsPage/6523.02003-04?OpenDocument
22. Belshe RB, Mendelman PM, Treanor J, King J, Gruber WC, Piedra P, Bernstein DI, Hayden FG, Kotloff K, Zangwill K, Iacuzio D, Wolff M. The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children. N Engl J Med 1998, 338:1405-1412. 10.1056/NEJM199805143382002, 9580647.
23. Lambert S, O'Grady K-A, Gabriel S, Carter R, Nolan T. The cost of seasonal respiratory illnesses in Australian children: the dominance of patient and family costs and implications for vaccine use. Commun Dis Intell 2004, 28:510-516.
24. Lambert SB, O'Grady KF, Gabriel SH, Nolan TM. Respiratory illness during winter: a cohort study of urban children from temperate Australia. J Paediatr Child Health 2005, 41:125-129. 10.1111/j.1440-1754.2005.00561.x, 15790323.
25. Australian Bureau of Statistics: Australian Economic Indicators: May 2004. Volume 1350.0. , http://www.ausstats.abs.gov.au/ausstats/subscriber.nsf/0/AE8854FC4CF8E64DCA256E86000072C6/$File/13500_may%202004.pdf
26. Australian Bureau of Statistics: Average weekly earnings Australia: May 2004. Volume 6032.0. , http://www.ausstats.abs.gov.au/ausstats/subscriber.nsf/0/F83D0C063BC688AECA256EF40076CA77/$File/63020_may%202004.pdf
27. Briggs A, Gray A. The distribution of health care costs and their statistical analysis for economic evaluation. J Health Serv Res Policy 1998, 3:233-245.
28. Jordan WS, Badger GF, Dingle JH. A study of illness in a group of Cleveland families. XVI. The epidemiology of influenza, 1948-1953. Am J Hyg 1958, 68:169-189.
29. Monto AS, Davenport FM, Napier JA, Francis T. Modification of an outbreak of influenza in Tecumseh, Michigan by vaccination of schoolchildren. J Infect Dis 1970, 122:16-25.
30. Taber LH, Paredes A, Glezen WP, Couch RB. Infection with influenza A/Victoria virus in Houston families, 1976. J Hyg (Lond) 1981, 86:303-313.
31. Fox JP, Hall CE, Cooney MK, Foy HM. Influenzavirus infections in Seattle families, 1975-1979. I. Study design, methods and the occurrence of infections by time and age. Am J Epidemiol 1982, 116:212-227.
32. Izurieta HS, Thompson WW, Kramarz P, Shay DK, Davis RL, DeStefano F, Black S, Shinefield H, Fukuda K. Influenza and the rates of hospitalization for respiratory disease among infants and young children. N Engl J Med 2000, 342:232-239. 10.1056/NEJM200001273420402, 10648764.
33. Neuzil KM, Mellen BG, Wright PF, Mitchel EF, Griffin MR. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. N Engl J Med 2000, 342:225-231. 10.1056/NEJM200001273420401, 10648763.
34. Hurwitz ES, Haber M, Chang A, Shope T, Teo S, Ginsberg M, Waecker N, Cox NJ. Effectiveness of influenza vaccination of day care children in reducing influenza-related morbidity among household contacts. JAMA 2000, 284:1677-1682. 10.1001/jama.284.13.1677, 11015798.
35. Esposito S, Marchisio P, Cavagna R, Gironi S, Bosis S, Lambertini L, Droghetti R, Principi N. Effectiveness of influenza vaccination of children with recurrent respiratory tract infections in reducing respiratory-related morbidity within the households. Vaccine 2003, 21:3162-3168. 10.1016/S0264-410X(03)00253-6, 12804844.
36. Ghendon YZ, Kaira AN, Elshina GA. The effect of mass influenza immunization in children on the morbidity of the unvaccinated elderly. Epidemiol Infect 2006, 134:71-78. 10.1017/S0950268805005650, 16316494.
37. Nokso-Koivisto J, Kinnari TJ, Lindahl P, Hovi T, Pitkaranta A. Human picornavirus and coronavirus RNA in nasopharynx of children without concurrent respiratory symptoms. J Med Virol 2002, 66:417-420. 10.1002/jmv.2161, 11793396.
38. van Benten I, Koopman L, Niesters B, Hop W, van Middelkoop B, de Waal L, van Drunen K, Osterhaus A, Neijens H, Fokkens W. Predominance of rhinovirus in the nose of symptomatic and asymptomatic infants. Pediatr Allergy Immunol 2003, 14:363-370. 10.1034/j.1399-3038.2003.00064.x, 14641606.
39. Hall JL, Katz BZ. Cost of influenza hospitalization at a tertiary care children's hospital and its impact on the cost-benefit analysis of the recommendation for universal influenza immunization in children age 6 to 23 months. J Pediatr 2005, 147:807-811. 10.1016/j.jpeds.2005.06.031, 16356436.
40. Ampofo K, Gesteland PH, Bender J, Mills M, Daly J, Samore M, Byington C, Pavia AT, Srivastava R. Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection. Pediatrics 2006, 118:2409-2417. 10.1542/peds.2006-1475, 17142526.
41. Keren R, Zaoutis TE, Saddlemire S, Luan XQ, Coffin SE. Direct medical cost of influenza-related hospitalizations in children. Pediatrics 2006, 118:e1321-1327. 10.1542/peds.2006-0598, 17079533.
42. Meltzer MI, Cox NJ, Fukuda K. The economic impact of pandemic influenza in the United States: priorities for intervention. Emerg Infect Dis 1999, 5:659-671.
43. Luce BR, Zangwill KM, Palmer CS, Mendelman PM, Yan L, Wolff MC, Cho I, Marcy SM, Iacuzio D, Belshe RB. Cost-effectiveness analysis of an intranasal influenza vaccine for the prevention of influenza in healthy children. Pediatrics 2001, 108:e24. 10.1542/peds.108.2.e24, 11483834.
44. Meltzer MI, Neuzil KM, Griffin MR, Fukuda K. An economic analysis of annual influenza vaccination of children. Vaccine 2005, 23:1004-1014. 10.1016/j.vaccine.2004.07.040, 15620473.
45. Nichol KL, Mendelman P. Influence of clinical case definitions with differing levels of sensitivity and specificity on estimates of the relative and absolute health benefits of influenza vaccination among healthy working adults and implications for economic analyses. Virus Res 2004, 103:3-8. 10.1016/j.virusres.2004.02.005, 15163481.
46. Keren R, Wheeler A, Coffin SE, Zaoutis T, Hodinka R, Heydon K. ICD-9 codes for identifying influenza hospitalizations in children. Emerg Infect Dis 2006, 12:1603-1604.
47. Kusel MM, de Klerk NH, Holt PG, Kebadze T, Johnston SL, Sly PD. Role of respiratory viruses in acute upper and lower respiratory tract illness in the first year of life: a birth cohort study. Pediatr Infect Dis J 2006, 25:680-686. 10.1097/01.inf.0000226912.88900.a3, 16874165.
48. Legg JP, Warner JA, Johnston SL, Warner JO. Frequency of detection of picornaviruses and seven other respiratory pathogens in infants. Pediatr Infect Dis J 2005, 24:611-616. 10.1097/01.inf.0000168747.94999.aa, 15999002.
49. Heikkinen T, Silvennoinen H, Peltola V, Ziegler T, Vainionpaa R, Vuorinen T, Kainulainen L, Puhakka T, Jartti T, Toikka P, Lehtinen P, Routi T, Juven T. Burden of influenza in children in the community. J Infect Dis 2004, 190:1369-1373. 10.1086/424527, 15378427.
50. Bosis S, Esposito S, Niesters HG, Crovari P, Osterhaus AD, Principi N. Impact of human metapneumovirus in childhood: comparison with respiratory syncytial virus and influenza viruses. J Med Virol 2005, 75:101-104. 10.1002/jmv.20243, 15543589.
51. Ehlken B, Ihorst G, Lippert B, Rohwedder A, Petersen G, Schumacher M, Forster J. Economic impact of community-acquired and nosocomial lower respiratory tract infections in young children in Germany. Eur J Pediatr 2005, 164:607-615. 10.1007/s00431-005-1705-0, 15965766.
52. Turner J, Tran T, Birch C, Kelly H. Higher than normal seasonal influenza activity in Victoria, 2003. Commun Dis Intell 2004, 28:175-180.
53. Sculpher MJ. The role and estimation of productivity costs in economic evaluation. Economic evaluation in health care: merging theory with practice 2001, Oxford: Oxford University Press, Drummond MF, McGuire AE, 2.
54. Salo H, Kilpi T, Sintonen H, Linna M, Peltola V, Heikkinen T. Cost-effectiveness of influenza vaccination of healthy children. Vaccine 2006, 24:4934-4941. 10.1016/j.vaccine.2006.03.057, 16678945.
55. Johannesson M. Avoiding double-counting in pharmacoeconomic studies. Pharmacoeconomics 1997, 11:385-388.
56. Zambon M, Hays J, Webster A, Newman R, Keene O. Diagnosis of influenza in the community: relationship of clinical diagnosis to confirmed virological, serologic, or molecular detection of influenza. Arch Intern Med 2001, 161:2116-2122. 10.1001/archinte.161.17.2116, 11570941.
57. Nichol KL. The efficacy, effectiveness and cost-effectiveness of inactivated influenza virus vaccines. Vaccine 2003, 21:1769-1775. 10.1016/S0264-410X(03)00070-7, 12686092.
58. Piedra PA, Gaglani MJ, Kozinetz CA, Herschler G, Riggs M, Griffith M, Fewlass C, Watts M, Hessel C, Cordova J, Glezen WP. Herd immunity in adults against influenza-related illnesses with use of the trivalent-live attenuated influenza vaccine (CAIV-T) in children. Vaccine 2005, 23:1540-1548. 10.1016/j.vaccine.2004.09.025, 15694506.
59. Centers for Disease Control and Prevention Direct and indirect effects of routine vaccination of children with 7-valent pneumococcal conjugate vaccine on incidence of invasive pneumococcal disease - United States, 1998-2003. MMWR Morb Mortal Wkly Rep 2005, 54:893-897. Centers for Disease Control and Prevention.
60. Medicare statistics: average patient contribution per service, September 2004. Patient and bulk billed services out-of-hospital only. Table B6. , http://www.health.gov.au/internet/wcms/publishing.nsf/Content/medstat-sep04-tables-b/$file/tableb6.pdf
61. Medicare statistics: explanatory notes and definitions, September 2004. , http://www6.health.gov.au/internet/wcms/publishing.nsf/Content/medstat-sep04-exp-def
62. Medicare Benefits Schedule Book operating from 1 November 2002. , http://www.health.gov.au/internet/wcms/publishing.nsf/Content/16A60E2104172E3ACA25729E007B413B/$File/MBSNov2002..pdf
63. Medicare Benefits Schedule Book operating from 1 November 2003. , http://www.health.gov.au/internet/wcms/publishing.nsf/Content/16A60E2104172E3ACA25729E007B413B/$File/MBSNov03.pdf
64. Manual of Resource Items and their Associated Costs for use in submissions to the Pharmaceutical Benefits Advisory Committee involving economic evaluation. , http://www.health.gov.au/internet/wcms/Publishing.nsf/Content/health-pbs-general-pubs-manual-appendix3.htm
65. National Hospital Cost Data Collection. Hospital Reference Manual, Round 6, for the 2002-2003 financial year. , http://www.health.gov.au/internet/wcms/publishing.nsf/Content/D255D3332CCE8231CA256F480012F2DF/$File/_R7CWVICEst.pdf
66. National Hospital Cost Data Collection. Hospital Reference Manual, Round 6, for the 2003-2004 financial year. , http://www.health.gov.au/internet/wcms/publishing.nsf/Content/BB918453BBAB7AB0CA2570C1000230B0/$File/_R8CWVICEst.pdf