A Zn(II)-glycine complex suppresses UVB-induced melanin production by stimulating metallothionein expression

International Journal of Cosmetic Science

Volumn 30, Issue 2, 2008, Pages 105-112

  Ochiai, Y ^a   Kaburagi, S ^a   Okano, Y ^a   Masaki, H ^a   Ichihashi, M ^b   Funasaka, Y ^c   Sakurai, H ^d  

^a NIKKOL Group Cosmos Technical Center Co   (Japan)

^b Sun Care Institute   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Keratinocytes; Melanocytes; Metallothionein; Reactive oxygen species; Ultraviolet

Indexed keywords

GLYCINE; MELANOCORTIN; METALLOTHIONEIN; PROSTAGLANDIN E2; ZINC;

ARTICLE; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; KERATINOCYTE; MELANOGENESIS; OXIDATIVE STRESS; PROTEIN EXPRESSION; ULTRAVIOLET B RADIATION;

CATIONS, DIVALENT; CELL LINE; DINOPROSTONE; GLYCINE; HUMANS; KERATINOCYTES; MELANINS; MELANOCYTES; METALLOTHIONEIN; ORGANOMETALLIC COMPOUNDS; PRO-OPIOMELANOCORTIN; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; ULTRAVIOLET RAYS; ZINC COMPOUNDS;

EID: 40849085418     PISSN: 01425463     EISSN: 14682494     Source Type: Journal    
DOI: 10.1111/j.1468-2494.2007.00423.x     Document Type: Article

References (26)

1. Kligman, L.H. Kligman, A.M. The nature of photo-aging: its prevention and repair. Photodermatology 3, 215 227 (1986).
2. Hachiya, A., Kobayashi, A., Yoshida, Y., Kitahara, T., Takema, Y. Imokawa, G. Biphasic expression of two paracrine melanogenic cytokines, stem cell factor and endothelin-1, in ultraviolet B-induced human melanogenesis. Am. J. Pathol. 165, 2099 2109 (2004).
3. 2 on the configuration of normal human melanocytes in vitro. J. Invest. Dermatol. 89, 299 301 (1987).
4. Bolognia, J., Murray, M. Pawelek, J. UVB-induced melanogenesis may be mediated through the MSH-receptor system. J. Invest. Dermatol. 92, 651 656 (1989).
5. Kiritoshi, S., Nishikawa, T., Sonoda, K. et al. Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. Diabetes 52, 2570 2577 (2003).
6. Chakraborty, A.K., Funasaka, Y., Slominski, A., Ermak, G., Hwang, J., Pawelek, J.M. Ichihashi, M. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B. Biochim. Biophys. Acta 1313, 130 138 (1996).
7. Romero-Graillet, C., Aberdam, E., Biagoli, N., Massabni, W., Ortonne, J-P. Ballotti, R. Ultraviolet B radiation acts through the nitric oxide and cGMP signal transduction pathway to stimulate melanogenesis in human melanocytes. J. Biol. Chem. 271, 28052 28056 (1996).
8. Ochiai, Y., Kaburagi, S., Obayashi, K. et al. A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties. J. Dermatol. Sci. 44, 37 44 (2006).
9. Funasaka, Y., Komoto, M. Ichihashi, M. Depigmenting effect of alpha-tocopheryl ferulate on normal human melanocytes. Pigment Cell Res. 13, 170 174 (2000).
10. Kagi, J.H. Overview of metallothionein. Methods Enzymol. 205, 613 626 (1991).
11. Sato, M. Bremner, I. Oxygen free radicals and metallothionein. Free Radic. Biol. Med. 14, 325 337 (1993).
12. 3-induced metallothionein in photoprotection against UVB injury in mouse skin and cultured rat keratinocytes. J. Dermatol. Sci. 9, 203 208 (1995).
13. Baba, T., Nakano, H., Tamai, K., Sawamura, D., Hanada, K., Hashimoto, I. Arima, Y. Inhibitory effect of beta-thujaplicin on ultraviolet B-induced apoptosis in mouse keratinocytes. J. Invest. Dermatol. 110, 24 28 (1998).
14. Ota, T., Hanada, K. Hashimoto, I. The effect of cold stress on UVB injury in mouse skin and cultured keratinocytes. Photochem. Photobiol. 64, 984 987 (1996).
15. Sasaki, M., Kizawa, K., Igarashi, S., Horikoshi, T., Uchiwa, H. Miyachi, Y. Suppression of melanogenesis by induction of endogenous intracellular metallothionein in human melanocytes. Exp. Dermatol. 13, 465 471 (2004).
16. Masaki, H., Ochiai, Y., Obayashi, K. et al. A zinc (II) complex of glycine reduces oxidative stress of epidermal cells, HaCaT keratinocytes and normal human keratinocytes by inducing metallothionein. J. Dermatol. Sci. 45, 73 75 (2007).
17. Boukamp, P., Petrussevska, R.T., Breitkreutz, D., Hornung, J., Markham, A. Fusenig, N.E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 106, 761 771 (1988).
18. 2) coordination mode. Chem. Pharm. Bull. 49, 652 654 (2001).
19. 2 but not MSH stimulate the proliferation of pigment cells in the pinnal epidermis of the DBA/2 mouse. J. Invest. Dermatol. 86, 433 437 (1986).
20. Masaki, H. Sakurai, H. Increased generation of hydrogen peroxide possibly from mitochondrial respiratory chain after UVB irradiation of murine fibroblasts. J. Dermatol. Sci. 14, 207 216 (1997).
21. Beak, S.M., Lee, Y.S. Kim, J.A. NADPH oxidase and cyclooxygenase mediate the ultraviolet B-induced generation of reactive oxygen species and activation of nuclear factor-kappaB in HaCaT human keratinocytes. Biochimie 86, 425 429 (2004).
22. Tobin, D. Thody, A.J. The superoxide anion may mediate short- but not long-term effects of ultraviolet radiation on melanogenesis. Exp. Dermatol. 3, 99 105 (1994).
23. Thornalley, P.J. Vasak, M. Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. Biochim. Biophys. Acta 21, 36 44 (1985).
24. 2 production in the photosensitivity in xeroderma pigmentosum group A model mice. J. Invest. Dermatol. 114, 241 246 (2000).
25. Levadouz-Martin, M., Hesketh, J.E., Beattie, J.H. Wallace, H.M. Influence of metallothionein-1 localization on its function. Biochem. J. 355, 473 479 (2001).
26. Jourdan, E., Marie Jeanne, R., Regine, S. Pascale, G. Zinc-metallothionein genoprotective effect is independent of the glutathione depletion in HaCaT keratinocytes after solar light irradiation. J. Cell. Biochem. 92, 631 640 (2004).