Association Between Abnormal Autofluorescence and Photoreceptor Disorganization in Retinitis Pigmentosa

American Journal of Ophthalmology

Volumn 145, Issue 4, 2008, Pages 687-694

  Murakami, Tomoaki ^a   Akimoto, Masayuki ^b   Ooto, Sotaro ^a   Suzuki, Takuya ^a   Ikeda, Hanako ^a   Kawagoe, Naoaki ^a   Takahashi, Masayo ^b   Yoshimura, Nagahisa ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; AUTOFLUORESCENCE; CLINICAL ARTICLE; ELECTRORETINOGRAPHY; EYE FUNDUS; FEMALE; HUMAN; MALE; OPTICAL COHERENCE TOMOGRAPHY; PERIMETRY; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA FOVEA; RETINA PIGMENT EPITHELIOPATHY; RETINITIS PIGMENTOSA; RETROSPECTIVE STUDY; STATISTICAL ANALYSIS; VISUAL FIELD;

DISEASE PROGRESSION; ELECTRORETINOGRAPHY; FEMALE; FLUORESCENCE; HUMANS; MALE; MIDDLE AGED; PERIMETRY; PHOTORECEPTORS, VERTEBRATE; PIGMENT EPITHELIUM OF EYE; RETINITIS PIGMENTOSA; RETROSPECTIVE STUDIES; TOMOGRAPHY, OPTICAL COHERENCE; VISION DISORDERS; VISUAL ACUITY; VISUAL FIELDS;

EID: 40849083512     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2007.11.018     Document Type: Article

References (31)

1. Szamier R.B., and Berson E.L. Retinal ultra-structure in advanced retinitis pigmentosa. Invest Ophthalmol Vis Sci 16 (1977) 947-962
2. Kolb H., and Gouras P. Electron microscopic observations of human retinitis pigmentosa, dominantly inherited. Invest Ophthalmol 13 (1974) 487-498
3. Rodrigues M.M., Wiggert B., T'So M.O., and Chader G.J. Retinitis pigmentosa: immunohistochemical and biochemical studies of the retina. Can J Ophthalmol 21 (1986) 79-83
4. Tamai M. [Progress in pathogenesis and therapeutic research in retinitis pigmentosa and age-related macular degeneration]. Nippon Ganka Gakkai Zasshi 108 (2004) 750-768 discussion 769
5. von Ruckmann A., Fitzke F.W., and Bird A.C. Distribution of fundus autofluorescence with a scanning laser ophthalmoscope. Br J Ophthalmol 79 (1995) 407-412
6. Kennedy C.J., Rakoczy P.E., and Constable I.J. Lipofuscin of the retinal pigment epithelium: a review. Eye 9 (1995) 763-771
7. von Ruckmann A., Fitzke F.W., and Bird A.C. Distribution of pigment epithelium autofluorescence in retinal disease state recorded in vivo and its change over time. Graefes Arch Clin Exp Ophthalmol 237 (1999) 1-9
8. Robson A.G., El-Amir A., Bailey C., et al. Pattern ERG correlates of abnormal fundus autofluorescence in patients with retinitis pigmentosa and normal visual acuity. Invest Ophthalmol Vis Sci 44 (2003) 3544-3550
9. Robson A.G., Saihan Z., Jenkins S.A., et al. Functional characterization and serial imaging of abnormal fundus autofluorescence in patients with retinitis pigmentosa and normal visual acuity. Br J Ophthalmol 90 (2006) 472-479
10. Popovic P., Jarc-Vidmar M., and Hawlina M. Abnormal fundus autofluorescence in relation to retinal function in patients with retinitis pigmentosa. Graefes Arch Clin Exp Ophthalmol 243 (2005) 1018-1027
11. Costa R.A., Calucci D., Skaf M., et al. Optical coherence tomography 3: automatic delineation of the outer neural retinal boundary and its influence on retinal thickness measurements. Invest Ophthalmol Vis Sci 45 (2004) 2399-2406
12. Eandi C.M., Chung J.E., Cardillo-Piccolino F., and Spaide R.F. Optical coherence tomography in unilateral resolved central serous chorioretinopathy. Retina 25 (2005) 417-421
13. Sandberg M.A., Brockhurst R.J., Gaudio A.R., and Berson E.L. The association between visual acuity and central retinal thickness in retinitis pigmentosa. Invest Opht Sci 46 (2005) 3349-3354
14. Lorenz B., Wabbels B., Wegscheider E., Hamel C.P., Drexler W., and Preising M.N. Lack of fundus autofluorescence to 488 nanometers from childhood on in patients with early-onset severe retinal dystrophy associated with mutations in RPE65. Ophthalmology 111 (2004) 1585-1594
15. Cunha-Vaz J.G., and Travassos A. Breakdown of the blood-retinal barriers and cystoid macular edema. Surv Ophthalmol 28 (1984) S485-S492
16. Hamada S., Yoshida K., and Chihara E. Optical coherence tomography images of retinitis pigmentosa. Ophthalmic Surg Lasers 31 (2000) 253-256
17. Li Q., Timmers A.M., Hunter K., et al. Noninvasive imaging by optical coherence tomography to monitor retinal degeneration in the mouse. Invest Ophthalmol Vis Sci 42 (2001) 2981-2989
18. Jacobson S.G., Aleman T.S., Cideciyan A.V., et al. Identifying photoreceptors in blind eyes caused by RPE65 mutations: prerequisite for human gene therapy success. Proc Natl Acad Sci U S A 102 (2005) 6177-6182
19. Nathans J. Rhodopsin: structure, function, and genetics. Biochemistry 31 (1992) 4923-4931
20. Dryja T.P., McGee T.L., Reichel E., et al. A point mutation of the rhodopsin gene in one form of retinitis pigmentosa. Nature 343 (1990) 364-366
21. Farrar G.J., Kenna P., Redmond R., et al. Autosomal dominant retinitis pigmentosa: absence of the rhodopsin proline-histidine substitution (codon 23) in pedigrees from Europe. Am J Hum Genet 47 (1990) 941-945
22. McLaughlin M.E., Sandberg M.A., Berson E.L., and Dryja T.P. Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa. Nat Genet 4 (1993) 130-134
23. Farber D.B. From mice to men: the cyclic GMP phosphodiesterase gene in vision and disease. The Proctor Lecture. Invest Ophthalmol Vis Sci 36 (1995) 263-275
24. Wada Y., and Tamai M. [Molecular genetic analysis for Japanese patients with autosomal dominant retinitis pigmentosa]. Nippon Ganka Gakkai Zasshi 107 (2003) 687-694
25. Auricchio A., and Rolling F. Adeno-associated viral vectors for retinal gene transfer and treatment of retinal diseases. Curr Gene Ther 5 (2005) 339-348
26. Bennett J. Strategies for delivery of rod-derived cone viability factor. Retina 25 (2005) S47
27. Li L.X., and Turner J.E. Inherited retinal dystrophy in the RCS rat: prevention of photoreceptor degeneration by pigment epithelial cell transplantation. Exp Eye Res 47 (1988) 911-917
28. Rezai K.A., Lappas A., Farrokh-siar L., Kohen L., Wiedemann P., and Heimann K. Iris pigment epithelial cells of long evans rats demonstrate phagocytic activity. Exp Eye Res 65 (1997) 23-29
29. Lappas A., Weinberger A.W., Foerster A.M., Kube T., Rezai K.A., and Kirchhof B. Iris pigment epithelial cell translocation in exudative age-related macular degeneration. A pilot study in patients. Graefes Arch Clin Exp Ophthalmol 238 (2000) 631-641
30. Haruta M., Sasai Y., Kawasaki H., et al. In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells. Invest Ophthalmol Vis Sci 45 (2004) 1020-1025
31. Ikeda H., Osakada F., Watanabe K., et al. Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells. Proc Natl Acad Sci U S A 102 (2005) 11331-11336