Pyrophosphate and tripolyphosphate affect firefly luciferase luminescence because they act as substrates and not as allosteric effectors

FEBS Journal

Volumn 275, Issue 7, 2008, Pages 1500-1509

  Fontes, Rui ^a   Fernandes, Diogo ^a,b   Peralta, Filipe ^b   Fraga, Hugo ^b,c   Maio, Inês ^a   Esteves Da Silva, Joaquim C G ^b  

^a University of Porto   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Dehydroluciferyl adenylate; Dinucleoside polyphosphates; Firefly luciferase; Pyrophosphate; Tripolyphosphate

Indexed keywords

ADENOSINE PHOSPHATE; CYTIDINE TRIPHOSPHATE; DEHYDROLUCIFERYL ADENYLATE; FIREFLY LUCIFERASE; NUCLEOSIDE TRIPHOSPHATE; PYROPHOSPHATE; TRIPOLYPHOSPHATE; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ALLOSTERISM; ARTICLE; BIOLUMINESCENCE; CONCENTRATION (PARAMETERS); ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; LUMINESCENCE; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ANIMALS; DIPHOSPHATES; FIREFLIES; LUCIFERASES, FIREFLY; LUMINESCENCE; LUMINESCENT AGENTS; POLYPHOSPHATES; PYROPHOSPHATASES; SUBSTRATE SPECIFICITY;

EID: 40749153596     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06309.x     Document Type: Article

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