In vivo pharmacokinetic studies of prodrugs of ibuprofen

Indian Journal of Pharmaceutical Sciences

Volumn 69, Issue 6, 2007, Pages 824-827

  Doshi, Abha ^a,b   Deshpande, S ^a  

^a SNDT WOMEN S UNIVERSITY   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDASE; IBUPROFEN; N (MORPHOLINOMETHYL)IBUPROFENAMIDE; N (PIPERIDINOMETHYL)IBUPROFENAMIDE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG HALF LIFE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IN VIVO STUDY; NONHUMAN; RABBIT;

EID: 40749130499     PISSN: 0250474X     EISSN: None     Source Type: Journal    
DOI: 10.4103/0250-474X.39444     Document Type: Article

References (7)

1. Doshi A, Samant SD, Deshpande SG. Prodrus of Ibuprofen I. Preparation and Physico-chemical propertes. Indian J Pharm Sci 2002;64:440-4.
2. Doshi A, Deshpande SG. Prodrugs of Ibuprofen II-Kinetics of decomposition of N-Mannich bases prodrugs. Indian J Pharm Sci 2002;64:445-8.
3. Johansen M, Bundgaard H. Pro-drugs as drug delivery systems XIII: Kinetics of decomposition of N-Mannich bases of salicylamide and assessment of their suitability as possible pro-drugs for amines. Int J Pharm 1980;7:119-27.
4. Bundgaard H, Johansen M. Prodrugs as drug delivery systems IV: N-mannich bases as potential novel prodrugs for amides, ureides, amines, and other NH-acidic compounds. J Pharm Sci 1980;69:44-6.
5. Bundgaard H, Johansen M. Pro-drugs as drug delivery systems XIX: Bioreversiblf derivatization of aromatic amines by formation of N-Mannich bases with succinimide. Int J Pharm 1981;8:183-92.
6. Bundgaard H, Johansen M. Hydrolysis of N-Mannich bases and its consequences for the biological testing of such agents. Int J Pharm 1981;9:7-16.
7. Bundgaard H, Johansen M. Prodrugs as drug delivery systems XXIV. Arch Pharm Chem Sci Ed 1982;10:111-21.