Swellable matrices with carbopols for benzydamine-HCl delivery from bioadhesive oromucosal tablets

Farmacia

Volumn 56, Issue 1, 2008, Pages 83-91

  Popovici, Iuliana ^a   Ochiuz, Lǎcrm̌ioara ^a   Popa, Emanuela Antoneta ^b   Saramet G ^b   Dorneanu, V ^a   Spac A ^a   Lupuleasa, D ^b  

^a GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

"In vitro" release; Carbopols; Oromucosal bioadhesive tablets; Physico chemical characteristics

Indexed keywords

BENZYDAMINE; CARBOMER; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; POLYCARBOPHIL CALCIUM; STARCH;

ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DETERMINATION; DRUG RELEASE; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; PH; PHYSICAL CHEMISTRY; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS;

EID: 40749129620     PISSN: 00148237     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Italian Patent Application, Ser. No. 16898/6, File august 9, 1963
2. US Patent 630, 0358
3. The Merck Index, vol. I, ed. III, Merck Inc., N.Y., 2001: 1121
4. Index Nominum International Drug Directory, 18th ed., Ed. by Swiss Pharmaceutical Society, Medpharm. Scientific Publishers, Stuttgart, 2004: 133
5. Reynold J.E.F., Martindale - The Complete Drug Reference, ed. 32, Ed. K. Parfitt, Pharmaceutical Press, London, 1999: 21
6. Tantum verde. Clorhidrat de benzidaminǎ, CSC Pharmaceuticals, 2005
7. Calda P., Kellnerova R., Vanecek D., Bohnicek F., Hedejova H. - Tantum Rosa. Product monography, CSC Pharmaceuticals 2004: 1-17
8. Sweja Z. - The use of benzydamine·HCl in otolaryngology, Otolaryngology Pol. 2001, 55, 2: 217-221
9. Burgalassi S., Panichi L., Saetone M.F., Jacobsen J., Rassing M.R. - A novel mucoadhesive buccal drug delivery systems, Proc. 1st Meeting APGI/ APV, Budapest, 9-11 May 1995: 839-840
10. Machida J., Nagai T. - Bioadhesive preparations as topical dosage forms, in: Mathiowitz E., Cickering D.E. III, Lehr C.M.: Bioadhesive Drug Delivery Systems, Ed. A Dekker Inc., New York, 1999: 641-657
11. Colombo P., Bettini R., Sand P. - Swellable matrices for controlled drug delivery: gel-layer behavior, mechanisms and optimal performance, P. ST. T. 2000, 3, 6: 198-204
12. Popa E. A., Diug E., Popovici I., Śaramet G., Lupuliasa D., Arseni V. - 'Studiul fizic al comprimatelor biomucoadezive cu clorhidrat de benzidaminá Rev. Farmaceuticǎ a Moldovei (Chişinǔ), 2005, 4: 7-13