Independent predictors of cardiac parasympathetic dysfunction in type 2 diabetes mellitus

Singapore Medical Journal

Volumn 49, Issue 2, 2008, Pages 121-128

  Subbalakshmi, N K ^a   Adhikari, P M R ^a   Rajeev, A ^a   Asha, K ^a   Jeganathan, P S ^a  

^a KASTURBA MEDICAL COLLEGE   (India)

Author keywords

Diabetes mellitus; Heart rate variation; Parasympathetic dysfunction; Somatic neuropathy; Type 2 diabetes mellitus

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; AUTONOMIC NEUROPATHY; BREATHING; CHOLINERGIC SYSTEM; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETIC FOOT; DIABETIC NEUROPATHY; FEMALE; HEART RATE VARIABILITY; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; RETINOPATHY; SEX DIFFERENCE; VALSALVA MANEUVER; AGE; BODY POSTURE; CASE CONTROL STUDY; HEART FUNCTION TEST; HEART RATE; MIDDLE AGED; ORTHOSTATIC HYPOTENSION; PATHOPHYSIOLOGY; PHYSIOLOGY;

BIOLOGICAL MARKER;

ADULT; AGE FACTORS; AGED; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC NEUROPATHIES; FEMALE; HEART FUNCTION TESTS; HEART RATE; HUMANS; HYPOTENSION, ORTHOSTATIC; MALE; MIDDLE AGED; PARASYMPATHETIC NERVOUS SYSTEM; POSTURE; RESPIRATION; SEX FACTORS; VALSALVA MANEUVER;

EID: 40749116934     PISSN: 00375675     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Ewing DJ, Clarke BF. Diagnosis and management of diabetic autonomic neuropathy. Br Med J (Clin Res Ed) 1982; 285:916-8.
2. O'Brien IA, McFadden JP, Corrall RJ. The influence of autonomic neuropathy on mortality in insulin-dependent diabetes. Q J Med 1991; 79:495-502.
3. Navarro X, Kennedy WR, Sutherland DE. Autonomic neuropathy and survival in diabetes mellitus: effects of pancreas transplantation. Diabetologia 1991; 34(suppl 1):S108-12.
4. Watkins PJ, Edmonds ME. Sympathetic nerve failure in diabetes. Diabetologia 1983; 25:73-7.
5. Talman WT, Benaroch EE. Neural control of cardiac function. In: Dyck PJ, Thomas PK, Lambert EH, Bunge R, eds. Peripheral Neuropathy. Vol 1. 3rd ed. Philadelphia: W.B Saunders, 1992: 177-85.
6. Kennedy WR, Navarro X, Sakuta M, et al. Physiological and clinical correlates of cardiorespiratory reflexes in diabetes mellitus. Diabetes Care 1989; 12:399-408.
7. Wheeler T, Watkins PJ. Cardiac denervation in diabetics. Br Med J 1973; 4:584-6.
8. Weimer LH. Autonomic function. In: Evans RW, ed. Diagnostic Testing in Neurology. Philadelphia: W.B Saunders, 1999: 337-65.
9. Engstrom JW, Martin JB. Disorders of the autonomic nervous system. In: Braunwald E, Hauser SL, Fauci AS, et al, eds. Harrison's Principles of Internal Medicine. Vol 2. 15th ed. New York: McGraw-Hill, 2001: 2416-21.
10. O'Brien IA, O'Hare JP, Lewin IG, Corrall RJ. The prevalence of autonomic neuropathy in insulin-dependent diabetes mellitus: a controlled study based on heart rate variability. Q J Med 1986; 61:957-67.
11. Smith SA. Reduced sinus arrhythmia in diabetic autonomic neuropathy: diagnostic value of an age-related normal range. Br Med J (Clin Res Ed) 1982; 285:1599-601.
12. Low PA, Opfer-Gehrking TL, Proper CJ, Zimmerman I. The effect of aging on cardiac autonomic and postganglionic sudomotor function. Muscle Nerve 1990; 13:152-7.
13. Hilsted J, Jensen SB. A simple test for autonomic neuropathy in juvenile diabetics. Acta Med Scand 1979; 205:385-7.
14. Factors in development of diabetic neuropathy. Baseline analysis of neuropathy in feasibility phase of Diabetes Control and Complications Trial (DCCT). The DCCT Research Group. Diabetes 1988; 37:476-81.
15. Jaffe RS, Aoki TT, Rohatsch PL, Disbrow EA, Fung DL. Predicting cardiac autonomic neuropathy in type 1 (insulin-dependent) diabetes mellitus. Clin Auton Res 1995; 5:155-8.
16. Maser RE, Pfeifer MA, Dorman JS, et al. Diabetic autonomic neuropathy and cardiovascular risk. Pittsburgh epidemiology of diabetes complications study III. Arch Intern Med 1990; 150:1218-22.
17. Töyry JP, Niskanen LK, Mäntysaari MJ, Länsimies EA, Uusitupa MI. Occurrence, predictors, and clinical significance of autonomic neuropathy in NIDDM. Ten-year follow-up from the diagnosis. Diabetes 1996; 45:308-15.
18. Gundersen HJ, Neubauer B. A long-term diabetic autonomic nervous abnormality. Reduced variations in resting heart rate measured by a simple and sensitive method. Diabetologia 1977; 13:137-40.
19. Dyrberg T, Benn J, Christiansen SJ, Hilsted J, Nerup J. Prevalence of diabetic autonomic neuropathy measured by simple bedside tests. Diabetologia 1981; 20:190-4.
20. Straub RH, Zietz B, Palitzsch KD, Schölmerich J. Impact of disease duration on cardiovascular and pupillary autonomic nervous function in IDDM and NIDDM patients. Diabetes Care 1996; 19:960-7.
21. Veglio M, Carpano-Maglioli P, Tonda L, et al. Autonomic neuropathy in non-insulin-dependent diabetic patients: correlation with age, sex, duration and metabolic control of diabetes. Diabete Metab 1990; 16:200-6.
22. Lehtinen JM, Uustiupa M, Siitonen O, Pyörälä K. Prevalence of neuropathy in newly diagnosed NIDDM and nondiabetic control subjects. Diabetes 1989; 38:1307-13.
23. Pfeifer MA, Weinberg CR, Cook DL, et al. Autonomic neural dysfunction in recently diagnosed diabetic subjects. Diabetes Care 1984; 7:447-53.
24. Takahashi N, Nakagawa M, Saikawa T, et al. Effect of essential hypertension on cardiac autonomic function in type 2 diabetic patients. J Am Coll Cardiol 2001; 38:232-7.
25. Sima AA, Sugimoto K. Experimental diabetic neuropathy: an update. Diabetologia 1999; 42:773-88.
26. Airaksinen KE, Koistinen MJ, Ikäheimo MJ, et al. Effect of coronary artery disease on parasympathetic cardiovascular reflexes in NIDDM patients. Diabetes Care 1990; 13:83-6.
27. Krönert K, Holder K, Kuschmierz G, et al. Influence of cardiovascular diseases upon the results of the cardiovascular reflex tests in diabetic and nondiabetic subjects. Acta Diabetol Lat 1990; 27:1-10.
28. Valensi P, Huard JP, Giroux C, Attali JR. Factors involved in cardiac autonomic neuropathy in diabetic patients. J Diabetes Complications 1997; 11:180-7.
29. Mehta S, Mathur D, Chaturvedi M, Verma K. Incidence of cardiac autonomic neuropathy and its correlation with retinopathy, microalbuminuria and glycated haemoglobin in non-insulin dependent diabetes mellitus. J Indian Med Assoc 2002; 100:141-3.
30. Spallone V, Maiello MR, Cicconetti E, Menzinger G. Autonomic neuropathy and cardiovascular risk factors in insulin-dependent and non insulin-dependent diabetes. Diabetes Res Clin Pract 1997; 34:169-79.
31. Sundkvist G. Autonomic nervous function in asymptomatic diabetic patients with signs of peripheral neuropathy. Diabetes Care 1981; 4:529-34.
32. Weinberg CR, Pfeifer MA. Development of a predictive model for symptomatic neuropathy in diabetes. Diabetes 1986; 35:873-80.
33. Young RJ, Zhou YQ, Rodriguez E, et al. Variable relationship between peripheral somatic and autonomic neuropathy in patients with different syndromes of diabetic polyneuropathy. Diabetes 1986; 35:192-7.