메뉴 건너뛰기




Volumn 10, Issue 1, 2008, Pages 45-52

Pleiotropic effects: Should statins be considered an essential component in the treatment of dyslipidemia?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIBIOTIC AGENT; ATORVASTATIN; BETA CAROTENE; BILE ACID SEQUESTRANT; COLESTIPOL; FENOFIBRATE; GEMFIBROZIL; GLITAZONE DERIVATIVE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOVASTATIN PLUS NICOTINIC ACID; MEVINOLIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIOGLITAZONE; PLACEBO; PRAVASTATIN; ROSIGLITAZONE; ROSUVASTATIN; SIMVASTATIN;

EID: 40749104579     PISSN: 15233804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11883-008-0008-0     Document Type: Review
Times cited : (11)

References (50)
  • 1
    • 0023930868 scopus 로고
    • Report of the National Cholesterol Educational Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
    • The Expert Panel
    • The Expert Panel: Report of the National Cholesterol Educational Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Arch Intern Med 1988, 148:36-69.
    • (1988) Arch Intern Med , vol.148 , pp. 36-69
  • 2
    • 0028154543 scopus 로고
    • Second report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
    • National Cholesterol Education Program
    • National Cholesterol Education Program. Second report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). Circulation 1994, 89:1329-445.
    • (1994) Circulation , vol.89 , pp. 1329-1445
  • 3
    • 0030945777 scopus 로고    scopus 로고
    • The clinical-therapeutic implications of the Scandinavian Simvastatin Survival Study
    • Dujovne CA: The clinical-therapeutic implications of the Scandinavian Simvastatin Survival Study. Am J Cardiol 1997, 79:1387-1388.
    • (1997) Am J Cardiol , vol.79 , pp. 1387-1388
    • Dujovne, C.A.1
  • 4
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/ TexCAPS
    • for the AFCAPS/TexCAPS Research Group
    • Downs JR, Learfield M, Weis S, et al., for the AFCAPS/TexCAPS Research Group: Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/ TexCAPS. JAMA 1998, 279:1615-1622.
    • (1998) JAMA , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Learfield, M.2    Weis, S.3
  • 5
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • for the West of Scotland Coronary Prevention Study Group
    • Shepherd J, Cobbe SM, Ford I, et al., for the West of Scotland Coronary Prevention Study Group: Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995, 333:1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 6
    • 0037126729 scopus 로고    scopus 로고
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report
    • Third Report National Cholesterol Education Program NCEP
    • Third Report National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report. Circulation 2002, 106:3143.
    • (2002) Circulation , vol.106 , pp. 3143
  • 7
    • 26844564725 scopus 로고    scopus 로고
    • The potential relevance of the multiple lipid-independent (pleiotropic) effects of statins in the management of acute coronary syndromes
    • Ray KK, Cannon CP: The potential relevance of the multiple lipid-independent (pleiotropic) effects of statins in the management of acute coronary syndromes. J Am Coll Cardiol 2005, 46:1425-1433.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1425-1433
    • Ray, K.K.1    Cannon, C.P.2
  • 8
    • 0037164314 scopus 로고    scopus 로고
    • Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomized controlled trial. PROspective Study of Pravastatin in the Elderly at Risk
    • PROSPER study group
    • Shepherd J, Blauw GJ, Murphy MB, et al, PROSPER study group: Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomized controlled trial. PROspective Study of Pravastatin in the Elderly at Risk. Lancet 2002, 360:1623-1630.
    • (2002) Lancet , vol.360 , pp. 1623-1630
    • Shepherd, J.1    Blauw, G.J.2    Murphy, M.B.3
  • 9
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
    • ASCOT investigators
    • Sever PS, Dahlof B, Poulter NR, et al., ASCOT investigators: Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003, 361:1149-1158.
    • (2003) Lancet , vol.361 , pp. 1149-1158
    • Sever, P.S.1    Dahlof, B.2    Poulter, N.R.3
  • 10
    • 33645524176 scopus 로고    scopus 로고
    • Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: The ASTEROID trial
    • for the ASTEROID Investigators
    • Nissen SE, Nicholls SJ, Sipahi I, et al., for the ASTEROID Investigators: Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 2006, 295:1556-1565.
    • (2006) JAMA , vol.295 , pp. 1556-1565
    • Nissen, S.E.1    Nicholls, S.J.2    Sipahi, I.3
  • 11
    • 0036382099 scopus 로고    scopus 로고
    • Clinical significance of pleiotropic effects of statins: Lipid reduction and beyond
    • Auer J, Berent R, Weber T, et al.: Clinical significance of pleiotropic effects of statins: lipid reduction and beyond. Curr Med Chem 2002, 9:1831-1850.
    • (2002) Curr Med Chem , vol.9 , pp. 1831-1850
    • Auer, J.1    Berent, R.2    Weber, T.3
  • 12
    • 22144475853 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-mehtylglutaryl-coenzyme A reductase inhibitors: Candidate mechanisms for anti-lipid deposition in blood vessels
    • Kamai T, Metsumoto N, Koitabashi Y, et al.: Pleiotropic effects of 3-hydroxy-3-mehtylglutaryl-coenzyme A reductase inhibitors: candidate mechanisms for anti-lipid deposition in blood vessels. Curr Med Chem 2005, 3:195-201.
    • (2005) Curr Med Chem , vol.3 , pp. 195-201
    • Kamai, T.1    Metsumoto, N.2    Koitabashi, Y.3
  • 13
    • 23944445364 scopus 로고    scopus 로고
    • Effects of statins on HMG-CoA reductase inhibition beyond low-density lipoprotein cholesterol
    • Liao JK: Effects of statins on HMG-CoA reductase inhibition beyond low-density lipoprotein cholesterol. Am J Cardiol 2005, 96(suppl):24F-33F.
    • (2005) Am J Cardiol , vol.96 , Issue.SUPPL.
    • Liao, J.K.1
  • 14
    • 0022595639 scopus 로고
    • Platelet function in hypercholesterolemics before end after hypolipidemic drug therapy
    • Zucker ML, Trowbridge C, Krehbeil P, et al.: Platelet function in hypercholesterolemics before end after hypolipidemic drug therapy. Haemostasis 1986, 16:57-64.
    • (1986) Haemostasis , vol.16 , pp. 57-64
    • Zucker, M.L.1    Trowbridge, C.2    Krehbeil, P.3
  • 15
    • 33947497258 scopus 로고    scopus 로고
    • Ongoing clinical trials of the pleiotropic effects of statins
    • Davignon J, Leiter LA: Ongoing clinical trials of the pleiotropic effects of statins. Vasc Health Risk Manag 2005, 1:29-40.
    • (2005) Vasc Health Risk Manag , vol.1 , pp. 29-40
    • Davignon, J.1    Leiter, L.A.2
  • 16
    • 33751180331 scopus 로고    scopus 로고
    • Beyond lipid lowering what have we learned about the benefits of statins from the acute coronary syndromes trials?
    • Ray KK, Cannon CP, Ganz P: Beyond lipid lowering what have we learned about the benefits of statins from the acute coronary syndromes trials? Am J Cardiol 2006, 98(Suppl):18P-25P.
    • (2006) Am J Cardiol , vol.98 , Issue.SUPPL.
    • Ray, K.K.1    Cannon, C.P.2    Ganz, P.3
  • 17
    • 0032554333 scopus 로고    scopus 로고
    • Effect of atorvastatin on plasma fibrinogen
    • Wierzbicki AS, Lumb PJ, Semra YK, et al.: Effect of atorvastatin on plasma fibrinogen. Lancet 1998, 351:569-570.
    • (1998) Lancet , vol.351 , pp. 569-570
    • Wierzbicki, A.S.1    Lumb, P.J.2    Semra, Y.K.3
  • 19
    • 0036771113 scopus 로고    scopus 로고
    • Pleiotropic effects of HMG-CoA reductase inhibitors
    • Bocan TM: Pleiotropic effects of HMG-CoA reductase inhibitors. Curr Opin Invest Drugs 2002, 3:1312-1317.
    • (2002) Curr Opin Invest Drugs , vol.3 , pp. 1312-1317
    • Bocan, T.M.1
  • 20
    • 0037432305 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis
    • Solomon DH, Karlson EW, Rimm EB, et al.: Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation 2003, 107:1303-1307.
    • (2003) Circulation , vol.107 , pp. 1303-1307
    • Solomon, D.H.1    Karlson, E.W.2    Rimm, E.B.3
  • 21
    • 0035676529 scopus 로고    scopus 로고
    • High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors
    • del Rincon ID, Williams K, Stern MP, et al.: High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 2001, 44:2737-2745.
    • (2001) Arthritis Rheum , vol.44 , pp. 2737-2745
    • del Rincon, I.D.1    Williams, K.2    Stern, M.P.3
  • 22
    • 23944446113 scopus 로고    scopus 로고
    • Early time to benefit with intensive statin treatment: Could it be the pleiotropic effects?
    • Ray KK, Cannon CP: Early time to benefit with intensive statin treatment: could it be the pleiotropic effects? Am J Cardiol 2005, 96(Suppl):54F-60F.
    • (2005) Am J Cardiol , vol.96 , Issue.SUPPL.
    • Ray, K.K.1    Cannon, C.P.2
  • 23
    • 11344279659 scopus 로고    scopus 로고
    • C-reactive protein levels and outcomes after statin therapy
    • Ridker PM, Cannon CP, Morrow D, et al.: C-reactive protein levels and outcomes after statin therapy. N Engl J Med 2005, 352:20-28.
    • (2005) N Engl J Med , vol.352 , pp. 20-28
    • Ridker, P.M.1    Cannon, C.P.2    Morrow, D.3
  • 24
    • 0037027478 scopus 로고    scopus 로고
    • Reduced progression of early carotid atherosclerosis after antibiotic treatment and Chlamydia pneumoniae seropositivity
    • Sander D, Winbeck K, Klingelhofer J, et al.: Reduced progression of early carotid atherosclerosis after antibiotic treatment and Chlamydia pneumoniae seropositivity. Circulation 2002, 106:2428-2433.
    • (2002) Circulation , vol.106 , pp. 2428-2433
    • Sander, D.1    Winbeck, K.2    Klingelhofer, J.3
  • 25
    • 34248641015 scopus 로고    scopus 로고
    • C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: Moving an inflammatory hypothesis toward consensus
    • Ridker PM: C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus. J Am Coll Cardiol 2007, 49:2129-2138.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2129-2138
    • Ridker, P.M.1
  • 26
    • 34248342266 scopus 로고    scopus 로고
    • Low-density lipoprotein-dependent and -independent effects of cholesterol-lowering therapies on C-reactive protein
    • Kinlay S: Low-density lipoprotein-dependent and -independent effects of cholesterol-lowering therapies on C-reactive protein. J Am Coll Cardiol 2007, 49:2003-2009.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2003-2009
    • Kinlay, S.1
  • 27
    • 33751171875 scopus 로고    scopus 로고
    • Oxidative biomarkers in the diagnosis and prognosis of cardiovascular disease
    • Tsimikas S: Oxidative biomarkers in the diagnosis and prognosis of cardiovascular disease. Am J Cardiol 2006, 98(Suppl):9P-17P.
    • (2006) Am J Cardiol , vol.98 , Issue.SUPPL.
    • Tsimikas, S.1
  • 28
    • 33751183978 scopus 로고    scopus 로고
    • Molecular basis of differences among statins and a comparison with antioxidant vitamins
    • Mason RP: Molecular basis of differences among statins and a comparison with antioxidant vitamins. Am J Cardiol 2006, 98(Suppl):34P-41P.
    • (2006) Am J Cardiol , vol.98 , Issue.SUPPL.
    • Mason, R.P.1
  • 29
    • 33751191849 scopus 로고    scopus 로고
    • Plaque stabilization: Can we turn theory into evidence?
    • Libby P, Sasiela W: Plaque stabilization: can we turn theory into evidence? Am J Cardiol 2006, 98(Suppl):26P-33P.
    • (2006) Am J Cardiol , vol.98 , Issue.SUPPL.
    • Libby, P.1    Sasiela, W.2
  • 30
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • Brown G, Albers J, Fisher L, et al.: Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med 1990, 323:1289-1298.
    • (1990) N Engl J Med , vol.323 , pp. 1289-1298
    • Brown, G.1    Albers, J.2    Fisher, L.3
  • 31
    • 0037235657 scopus 로고    scopus 로고
    • Pleiotropic effects of statins: How important are they in the prevention of vascular disease?
    • Mehta JL: Pleiotropic effects of statins: how important are they in the prevention of vascular disease? Endothelium 2003, 10:3-4.
    • (2003) Endothelium , vol.10 , pp. 3-4
    • Mehta, J.L.1
  • 34
    • 0142012111 scopus 로고    scopus 로고
    • A retrospective analysis of the effect of noncompliance on time to first major adverse cardiac event in LIPS
    • Lesaffre E, Kocmanova D, Lemos PA, et al.: A retrospective analysis of the effect of noncompliance on time to first major adverse cardiac event in LIPS. Clin Ther 2003, 25:2431-2447.
    • (2003) Clin Ther , vol.25 , pp. 2431-2447
    • Lesaffre, E.1    Kocmanova, D.2    Lemos, P.A.3
  • 35
    • 6944240055 scopus 로고    scopus 로고
    • Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: National registry of myocardial infarction
    • Spencer FA, Fonarow GC, Frederick PD, et al.: Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction. Arch Intern Med 2004, 164:2162-2168.
    • (2004) Arch Intern Med , vol.164 , pp. 2162-2168
    • Spencer, F.A.1    Fonarow, G.C.2    Frederick, P.D.3
  • 36
    • 6444234849 scopus 로고    scopus 로고
    • Group: There is no evidence for an increase in acute coronary syndromes after short-term abrupt discontinuation of statins in stable cardiac patients
    • McGowan MP; TNT Study Group: There is no evidence for an increase in acute coronary syndromes after short-term abrupt discontinuation of statins in stable cardiac patients. Circulation 2004, 110:2280-2282.
    • (2004) Circulation , vol.110 , pp. 2280-2282
    • McGowan, M.P.1    Study, T.N.T.2
  • 37
    • 10744228675 scopus 로고    scopus 로고
    • Platelet hyperactivity after statin treatment discontinuation
    • Puccetti L, Pasqui AL, Pastorelli, et al.: Platelet hyperactivity after statin treatment discontinuation. Thromb Haemost 2003, 90:476-482.
    • (2003) Thromb Haemost , vol.90 , pp. 476-482
    • Puccetti, L.1    Pasqui, A.L.2    Pastorelli3
  • 38
    • 33745759751 scopus 로고    scopus 로고
    • Effects of atorvastatin and atorvastatin withdrawal on soluble DC40L and adipocytokines in patients with hypercholeserolaemia
    • Chu CS, Lee KT, Lee MY, et al.: Effects of atorvastatin and atorvastatin withdrawal on soluble DC40L and adipocytokines in patients with hypercholeserolaemia. Acta Cardiol 2006, 61:263-269.
    • (2006) Acta Cardiol , vol.61 , pp. 263-269
    • Chu, C.S.1    Lee, K.T.2    Lee, M.Y.3
  • 39
    • 33748100587 scopus 로고    scopus 로고
    • Statin withdrawal: Clinical implications and molecular mechanisms
    • Cubeddu LX, Seamon MJ: Statin withdrawal: clinical implications and molecular mechanisms. Pharmacotherapy 2006, 26:1288-1296.
    • (2006) Pharmacotherapy , vol.26 , pp. 1288-1296
    • Cubeddu, L.X.1    Seamon, M.J.2
  • 40
    • 33645046407 scopus 로고    scopus 로고
    • Early effects on endothelial function of atorvastatin 40 mg twice daily and its withdrawal
    • Taneva E, Borucki K, Wiens L, et al.: Early effects on endothelial function of atorvastatin 40 mg twice daily and its withdrawal. Am J Cardiol 2006, 97:1002-1006.
    • (2006) Am J Cardiol , vol.97 , pp. 1002-1006
    • Taneva, E.1    Borucki, K.2    Wiens, L.3
  • 41
    • 0035913126 scopus 로고    scopus 로고
    • Measurement of endothelial function by brachial artery flow-mediated vasodilation
    • Vogel RA: Measurement of endothelial function by brachial artery flow-mediated vasodilation. Am J Cardiol 2001, 88:31E-34E.
    • (2001) Am J Cardiol , vol.88
    • Vogel, R.A.1
  • 42
    • 4344665253 scopus 로고    scopus 로고
    • Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: The role of nicotinic acid? A position paper developed by the European Consensus Panel on HDL-C
    • Chapman MJ, Assmann G, Fruchart JC, et al.: Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: the role of nicotinic acid? A position paper developed by the European Consensus Panel on HDL-C. Curr Med Res Opin 2004, 20:1253-1268.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1253-1268
    • Chapman, M.J.1    Assmann, G.2    Fruchart, J.C.3
  • 43
    • 33747038067 scopus 로고    scopus 로고
    • Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus
    • Lakshman MR, Gottipati CS, Narasimhan SJ, et al.: Inverse correlation of serum paraoxonase and homocysteine thiolactonase activities and antioxidant capacity of high-density lipoprotein with the severity of cardiovascular disease in persons with type 2 diabetes mellitus. Metabolism 2006, 55:1201-1206.
    • (2006) Metabolism , vol.55 , pp. 1201-1206
    • Lakshman, M.R.1    Gottipati, C.S.2    Narasimhan, S.J.3
  • 44
    • 0141570968 scopus 로고    scopus 로고
    • Mechanisms of high-density lipoprotein cholesterol effects on the endothelial function in hyperlipemia
    • Lupattelli G, Marchesi S, Lombardini R, et al.: Mechanisms of high-density lipoprotein cholesterol effects on the endothelial function in hyperlipemia. Metabolism 2003, 52:1191-1195.
    • (2003) Metabolism , vol.52 , pp. 1191-1195
    • Lupattelli, G.1    Marchesi, S.2    Lombardini, R.3
  • 45
    • 33750981853 scopus 로고    scopus 로고
    • Extralipid effects of micronized fenofibrate in dyslipidemic patients
    • Okopie AB, Haberka M, Madej A, et al.: Extralipid effects of micronized fenofibrate in dyslipidemic patients. Pharmacol Rep 2006, 58:729-735.
    • (2006) Pharmacol Rep , vol.58 , pp. 729-735
    • Okopie, A.B.1    Haberka, M.2    Madej, A.3
  • 46
    • 18744373337 scopus 로고    scopus 로고
    • High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: Results from the MIRACL trial
    • Olsson AG, Schwartz GG, Szarek M, et al.: High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACL trial. Eur Heart J 2005, 26:890-896.
    • (2005) Eur Heart J , vol.26 , pp. 890-896
    • Olsson, A.G.1    Schwartz, G.G.2    Szarek, M.3
  • 47
    • 0141928147 scopus 로고    scopus 로고
    • PPAR inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes
    • Mendez M, LaPointe MC: PPAR inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. Hypertension 2003, 42:844-850.
    • (2003) Hypertension , vol.42 , pp. 844-850
    • Mendez, M.1    LaPointe, M.C.2
  • 48
    • 40749144156 scopus 로고    scopus 로고
    • The vascular effects of TZDs: Stabilizing plaque in an unstable environment
    • Released April 26, 2006. Available at, Accessed on September 13, 2007
    • Nesto RW, Plutzky J: The vascular effects of TZDs: stabilizing plaque in an unstable environment. Online CME presentation by the University of Wisconsin School of Medicine and Public Health. Released April 26, 2006. Available at http://www.medscape.com/viewprogram/5173. Accessed on September 13, 2007.
    • Online CME presentation by the University of Wisconsin School of Medicine and Public Health
    • Nesto, R.W.1    Plutzky, J.2
  • 49
    • 0037097447 scopus 로고    scopus 로고
    • Side effects of statins: Hepatitis vs transaminitis, myositis vs CPKitis
    • Dujovne CA: Side effects of statins: hepatitis vs transaminitis, myositis vs CPKitis. Am J Cardiol 2002, 89:1411-1413.
    • (2002) Am J Cardiol , vol.89 , pp. 1411-1413
    • Dujovne, C.A.1
  • 50
    • 33748534819 scopus 로고    scopus 로고
    • Who should receive a statin these days?
    • Shepherd J: Who should receive a statin these days? J Intern Med 2006, 260:305-319.
    • (2006) J Intern Med , vol.260 , pp. 305-319
    • Shepherd, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.