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Volumn 62, Issue 3, 2008, Pages 173-178
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Synthesis of 4-butyl-1-substituted-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-ones as new class of H1-antihistaminic agents
a
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Author keywords
H1 Antihistaminic agents; Quinazolin 5 ones; Sedation
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Indexed keywords
4 BUTYL 1 (MORPHOLINYL METHYL) 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 1 (PIPERAZINYL METHYL) 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 1 (PIPERIDYL METHYL) 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 1 (PYRROLIDYL METHYL) 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 1 [(4 METHYLPIPERAZINYL) METHYL] 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 1 CHLOROMETHYL 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 1 METHYL 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 1 PROPYL 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
4 BUTYL ETHYL 4H [1,2,4] TRIAZOLO [4,3 A] QUINAZOLIN 5 ONE;
ANTIHISTAMINIC AGENT;
CHLORPHENIRAMINE MALEATE;
PHENIRAMINE AMINOSALICYLATE;
QUINAZOLINONE DERIVATIVE;
UNCLASSIFIED DRUG;
ADVERSE OUTCOME;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTICHOLINERGIC EFFECT;
ANTIHISTAMINIC ACTIVITY;
ARTICLE;
BRONCHOSPASM;
COMPARATIVE STUDY;
CONTROLLED STUDY;
CYCLIZATION;
DRUG ACTIVITY;
DRUG POTENCY;
DRUG SYNTHESIS;
GUINEA PIG;
IN VIVO STUDY;
MOUSE;
NONHUMAN;
PRIORITY JOURNAL;
SEDATION;
STATISTICAL SIGNIFICANCE;
ALGORITHMS;
ANIMALS;
BRONCHIAL SPASM;
CHLORPHENIRAMINE;
GUINEA PIGS;
HISTAMINE;
HISTAMINE H1 ANTAGONISTS;
HYPNOTICS AND SEDATIVES;
MAGNETIC RESONANCE SPECTROSCOPY;
MALE;
MASS SPECTROMETRY;
MICE;
MOTOR ACTIVITY;
QUINAZOLINES;
SPECTROPHOTOMETRY, INFRARED;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 40749097325
PISSN: 07533322
EISSN: None
Source Type: Journal
DOI: 10.1016/j.biopha.2007.08.025 Document Type: Article |
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Times cited : (20)
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References (12)
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