Increased platelet cholesterol and decreased percentage volume of platelets as a secondary risk factor for coronary artery disease

Pathophysiology of Haemostasis and Thrombosis

Volumn 36, Issue 1, 2008, Pages 45-51

  Ravindran, Resmi ^a,b   Krishnan, Lissy K ^a  

^a SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atherosclerosis; Cholesterol; Platelet indices

Indexed keywords

ADENOSINE DIPHOSPHATE; CHOLESTEROL; COLLAGEN;

ADULT; ARTICLE; CARDIOVASCULAR RISK; CELL LEVEL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; FEMALE; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; HYPERTENSION; LIPID BLOOD LEVEL; MALE; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; THROMBOCYTE VOLUME;

ADENOSINE DIPHOSPHATE; ATHEROSCLEROSIS; BLOOD PLATELETS; CELL SIZE; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; COLLAGEN; CORONARY DISEASE; DIABETES COMPLICATIONS; FEMALE; HUMANS; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIAS; HYPERTENSION; MALE; MEMBRANE LIPIDS; MIDDLE AGED; PLATELET AGGREGATION; PLATELET COUNT; RISK FACTORS; SMOKING; TRIGLYCERIDES;

EID: 40649126569     PISSN: 14248832     EISSN: None     Source Type: Journal    
DOI: 10.1159/000112639     Document Type: Article

References (35)

1. Castelli WP, Garrison RJ, Wilson PW, Abbott RD, Kalousdian S, Kannel WB: Incidence of coronary artery disease and lipoprotein cholesterol levels: the Framingham Study. J Am Med Assoc 1986;256:2835-2838.
2. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486-2497.
3. Korporaal SJ, Akkerman JW: Platelet activation by low density lipoprotein and high density lipoprotein. Pathophysiol Haemost Thromb 2006;35:270-280.
4. Aviram M, Brook JG: Platelet activation by plasma lipoproteins. Prog Cardiovasc Dis 1987;30:61-72.
5. Naqvi TZ, Shah PK, Ivey PA, Molloy MD, Thomas AM, Panicker S, Ahmed A, Cercek B, Kaul S: Evidence that high-density lipoprotein cholesterol is an independent predictor of acute platelet-dependent thrombus formation. Am J Cardiol 1999;84:1011-1017.
6. Schick BP, Schick PK: The effect of hypercholesterolemia on guinea pig platelets, erythrocytes and megakaryocytes. Biochim Biophys Acta 1985;833:291-302.
7. Martin JF, Slater DN, Kishk YT, Trowbridge EA: Platelet and megakaryocyte changes in cholesterol-induced experimental atherosclerosis. Atherosclerosis 1985;5:604-612.
8. Shattil SJ, Anaya-Galindo R, Bennett J, Colman RW, Cooper RA: Platelet hypersensitivity induced by cholesterol incorporation. J Clin Invest 1975;55:636-643.
9. Hochgraf E, Levy Y, Aviram M, Brook JG, Cogan U: Lovastatin decreases plasma and platelet cholesterol levels and normalizes elevated platelet fluidity and aggregation in hypercholesterolemic patients. Metabolism 1994;43:11-17.
10. Winocour PD: Platelet abnormalities in diabetes mellitus. Diabetes 1992;41:26-31.
11. Winocour PD, Kinlough-Rathbone RL, Morazain R, Mustard JF: The effect of dietary saturated fat and cholesterol in platelet function, platelet survival and response to continuous aortic injury in rats. Atherosclerosis 1987;65:37-50.
12. Dalal KB, Ebbe S, Mazoyer E, Carpenter D, Yee T: Biochemical and functional abnormalities in hypercholesterolemic rabbit platelets. Lipids 1990;25:86-92.
13. Tandon NN, Hoeg JM, Jamieson GA: Perfusion studies on the formation of mural thrombi with cholesterol-modified and hypercholesterolemic platelets. J Lab Clin Med 1985;105:157-163.
14. Dupont H, Dupont MA, Larrue J, Boisseau MR, Bricaud H: Megakaryopoiesis disturbances in atherosclerotic rabbits. Atherosclerosis 1987;63:15-26.
15. Stuart MJ, Gerrard JM, White JG: Effect of cholesterol on production of thromboxane B 2 by platelets in vitro. N Engl J Med 1980;302:6-10.
16. Giacomini A, Legovini P, Gessoni G, Antico F, Valverde S, Salvadego MM, Manoni F: Platelet count and parameters determined by the Bayer ADVIA 120 in reference subjects and patients. Clin Lab Haematol 2001;23:181-186.
17. Boos CJ, Beevers GD, Lip GY: Assessment of platelet activation indices using the ADVIA™ 120 amongst 'high-risk' patients with hypertension. Ann Med 2007;39:72-78.
18. Patrick CH, Lazarchick J, Stubbs T, Pittard WB: Mean platelet volume and platelet distribution width in the neonate. Am J Pediatr Hematol Oncol 1987;9:130-132.
19. Born GVR: Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature (London) 1962;194:927-929.
20. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502.
21. Gogstad GO, Krutnes MB, Hetland O, Solum NO: Comparison of protein and lipid composition of the human platelet alphagranule membrane and glycerol lysis membranes. Biochim Biophys Acta 1983;732:519-530.
22. Opper C, Clement C, Schwarz H, Krappe J, Steinmetz A, Schneider J, Wesemann W: Increased number of high sensitive platelets in hypercholesterolemia, cardiovascular diseases, and after incubation with cholesterol. Atherosclerosis 1995;113:211-217.
23. Kowalska MA, Tuzynski GP, Capuzzi DM: Plasma lipoproteins mediate platelet adhesion. Biochem Biophys Res Commun 1990;172:113-118.
24. Kruth HS: Platelet mediated cholesterol accumulation in cultured aortic smooth muscle cells. Science 1985;227:1243-1245.
25. Le Quan Sang KH, Mazeaud M, Astarie C, Duranthon V, Driss F, Devynck MA: Plasma lipids and platelet membrane fluidity in essential hypertension. Thromb Haemost 1993;69:70-76.
26. Nadar SK, Blann AD, Kamath S, Beevers DG, Lip GY: Platelet indexes in relation to target organ damage in high-risk hypertensive patients: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). J Am Coll Cardiol 2004;44:415-422.
27. Kjeldsen SE, Gjesdal K, Eide I, Aakesson I, Amundsen R, Foss OP, Leren P: Increased beta-thromboglobulin in essential hypertension: interactions between arterial plasma adrenaline, platelet function and blood lipids. Acta Med Scand 1983;213:369-373.
28. Pathansali R, Smith NM, Bath PM: Prothrombotic megakaryocyte and platelet changes in hypertension are reversed following treatment: a pilot study. Platelets 2001;12:144-149.
29. Andrioli G, Ortolani R, Fontana L, Gaino S, Bellavite P, Lechi C, Minuz P, Manzato F, Tridente G, Lechi A: Study of platelet adhesion in patients with uncomplicated hypertension. J Hypertens 1996;14:1215-1221.
30. Moser L, Callahan KS, Cheung AK, Stoddard GJ, Munger MA: ACE inhibitor effects on platelet function in stages I-II hypertension. J Cardiovasc Pharmacol 1997;30:461-467.
31. Preston RA, Jy W, Jimenez JJ, Mauro LM, Horstman LL, Valle M, Aime G, Ahn YS: Effects of severe hypertension on endothelial and platelet microparticles. Hypertension 2003;41:211-217.
32. van Oost BA, van Hien-Hagg IH, Veldhuyzen BF, Timmermans AP, Sixma JJ: Determination of the density distribution of human platelets - methodological aspects and comparison with other tests for platelet activation. Thromb Haemost 1982;47:239-243.
33. van Oost BA, Timmermans AP, Sixma JJ: Evidence that platelet density depends on the alpha-granule content in platelets. Blood 1984;63:482-485.
34. Vivic WJ, Weiss HJ: Evidence that platelet alpha-granules are a major determinant of platelet density: studies in storage pool deficiency. Thromb Haemost 1983;50:878-880.
35. Boneu B, Corberand J, Plante J, Bierme R: Evidence that platelet density and volume are not related to aging. Thromb Res 1977;10:475-486.