Extensive chromoblastomycosis caused by Fonsecaea pedrosoi successfully treated with a combination of amphotericin B and itraconazole

Medical Mycology

Volumn 46, Issue 2, 2008, Pages 179-184

  Paniz Mondolfi, A E ^a   Colella, M T ^b   Negrin D C ^b   Aranzazu, N ^c   Oliver, M ^c   Reyes Jaimes, O ^c   Perez Alvarez A M ^a  

^a Ministerio del Poder Popular para el Trabajo y Seguridad Social Venezuela   (Venezuela)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^c INSTITUTO DE BIOMEDICINA   (Venezuela)

Author keywords

Amphotericin B; Chromoblastomycosis; Chronic fungal infection; Extensive; Fonsecaea pedrosoi; Itraconazole

Indexed keywords

AMPHOTERICIN B; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; POTASSIUM CHLORIDE;

ADULT; ANAMNESIS; ARTICLE; CASE REPORT; CHROMOMYCOSIS; CLINICAL FEATURE; COLONY FORMING UNIT; COMBINATION CHEMOTHERAPY; CULTURE MEDIUM; DOSE RESPONSE; DRUG DOSE REDUCTION; DRUG TREATMENT FAILURE; FONSECAEA PEDROSOI; HUMAN; HUMAN TISSUE; HYPOKALEMIA; MALE; MICROSCOPY; MONOTHERAPY; PATHOGENESIS; SKIN BIOPSY; SKIN EXAMINATION; SPECIES IDENTIFICATION; SPOROGENESIS; TREATMENT DURATION;

ADULT; AMPHOTERICIN B; ANTIFUNGAL AGENTS; ASCOMYCOTA; CHROMOBLASTOMYCOSIS; DRUG THERAPY, COMBINATION; HUMANS; ITRACONAZOLE; MALE; MITOSPORIC FUNGI;

FONSECAEA PEDROSOI; FUNGI;

EID: 40649118793     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1080/13693780701721856     Document Type: Article

References (42)

1. Pang, KR, Wu, JJ, Huang, DB and Tyring, S. (2004) Subcutaneous fungal infections. Dermatol Ther, 17, pp. 523-531.
2. McGinnis, MR. (1983) Chromoblastomycosis and phaeohyphomycosis. New concepts, diagnosis, and mycology. J Am Acad Dermatol, 8, pp. 1-16.
3. De Hoog, GS, Atilli-Angelis, D. and Vicente, VA (2004) Molecular ecology and pathogenic potencial of Fosecaea species. Med Mycol, 42, pp. 406-416.
4. Queiroz-Telles, F., McGinnis, MR, Salkin, I. and Graybill, JR. (2003) Subcutaneous mycoses. Infect Dis Clin N Am, 17, pp. 59-85.
5. Padhye, AA, Hampton, AA and Hampton, MT (1996) Chromoblastomycosis caused by Exophiala spinifera. Clin Infect Dis, 22, pp. 331-335.
6. Rivitti, EA and Aoki, V. (1999) Deep fungal infections in tropical countries. Clin Dermatol, 17, pp. 171-190.
7. Yegres, JF, De Yegres, NR and Blanco, M. Perez (1996) Temas de Micologia Medica, pp. 87-102.
8. Queiroz-Telles, F., Purin, K. and Fillus, JN. (1992) Itraconazole in the treatment of chromoblastomycosis due to Fonsecaea pedrosoi. Int J Dermatol, 31, pp. 805-812.
9. Bayles, M. (1992) Tropical mycoses. Chemotherapy, 38, pp. 27-34.
10. Park, SG, Oh, SH and Suh, SB (2005) A case of chromoblastomycosis with an unusual clinical manifestation caused by Phialophora verrucosa on an unexposed area: Treatment with a combination of amphotericin B and 5-flucytosine. Br J Dermatol, 152, pp. 560-564.
11. Kinbara, T., Fukushiro, R. and Eryu, Y. (1982) Chromomycosis: Report of two cases successfully treated with topical heat therapy. Mykosen, 25, pp. 689-694.
12. Tagami, H., Ginoza, M. and Imaizumi, S. (1984) Successful treatment of chromoblastomycosis with topical heat therapy. J Am Acad Dermatol, 10, pp. 615-619.
13. Yanase, K. and Yamada, M. (1978) Pocket-warmer therapy of chromomycosis. Arch Dermatol, 114, p. 1095.
14. Bonifaz, A., Paredes-Solís, V. and Saul, A. (2004) Treating chromoblastomycosis with systemic antifungals. Expert Opin Pharmacother, 5, pp. 247-254.
15. Tanuma, H., Hiramutsu, M. and Mukai, H. (1999) Case report: A case of chromoblastomycosis effectively treated with terbinafine. Mycoses, 43, pp. 79-83.
16. Pérez-Blanco, M., Valles, R Hernández and Zeppenfeldt, G Fernández (2003) Ajoene and 5-fluorouacil in the topical treatment of Cladophialophora carrionii chromoblastomycosis in humans: A comparative open study. Med Mycol, 41, pp. 517-520.
17. Borelli, D. (1987) A clinical trial of itraconazole in the treatment of deep mycoses and leishmaniasis. Rev Infect Dis, 9, p. S57.
18. Bopp, C. (1976) Cura da cromoblastomicose por novo tratamento. Med Cut ILA, 4, pp. 285-292.
19. Astorga, E., Bonilla, E. and Martinez, C. (1981) Tratamiento de la cromoblastomicosis com la anfotericina-B y 5-fluorcitosina. Med Cut ILA, pp. 125-128.
20. Cucé, LC, Wroclawski, EL and Sampaio, SAP. (1980) Treatment of paracoccidioidomycosis, candidiasis, chromomycosis, lobomycosis and mycetoma with ketoconazole. Int J Dermatol, 19, pp. 405-408.
21. Kumar, B., Kaur, I. and Chaklraberti, A. (1991) Treatment of deep mycosis with itraconazole. Mycopathologia, 115, pp. 169-174.
22. Ungpakron, R. and Reangchainam, S. (2006) Pulse itraconazole 400 mg daily in the treatment of chromoblastomycosis. Clin Exp Dermatol, 31, pp. 245-247.
23. Restrepo, A., Gonzalez, A. and Gomez, I. (1998) Treatment of chromoblastomycosis with itraconazole. Ann NY Acad Sci, 544, pp. 504-516.
24. Franco, I., Gomes, I. and Restrepo, A. (1992) Saperconazole in the treatment in systemic and subcutaneous mycosis. Int J Dermatol, 31, pp. 725-729.
25. Cardona-Castro, N., Agudelo-Florez, P. and Restrepo-Molina, R. (1996) Chromoblastomycosis murine model and in vitro test to evaluate the sensitivity of Fonsecaea pedrosoi to ketoconazole, itraconazole and saperconazole. Mem Inst Oswaldo Cruz, 91, pp. 779-784.
26. Valle, AC, Wanke, B. and Lazera, MS (2001) Entomophtothoramycosis by Conidiobolus coronatus. Report of a case successfully treated with the combination of itraconazole and fluconazole. Rev Inst Med Trop Sao Paulo, 43, pp. 233-236.
27. Herbrecht, R. (2004) Posaconazole: A potent, extended-spectrum triazole anti-fungal for the treatment of serious fungal infections. Int J Clin Pract, 58, pp. 612-624.
28. Torres, HA, Hachem, RY and Chemaly, RF (2005) Posaconazole: A broad-spectrum triazole antifungal. Lancet Infect Dis, 5, pp. 775-785.
29. Espinel-Ingroff, A. (1998) Comparison of in vitro activities of the new triazole SCH56592 and the echinocandins MK-0991 (L-743,872) and LY303366 against opportunistic filamentous and dimorphic fungi and yeasts. J Clin Microbiol, 36, pp. 2950-2956.
30. Marco, F., Pfaller, MA and Messer, AF (1998) Antifungal activity of a new triazole, voriconazole (UK-109,496) compared with three other antifungal agents against clinical isolates of filamentous fungi. Med Mycol, 36, pp. 433-461.
31. Negroni, R., Tobon, A. and Bustamante, B. (2005) Posaconazole treatment of refractory eumycetoma and chromoblastomycosis. Rev Inst Med Trop Sao Paulo, 47, pp. 339-346.
32. Paugam, A. (2007) The latest data on posaconazole. Med Mal Infect, 37, pp. 71-76.
33. McClellan, KJ, Wiseman, LR and Markham, A. (1999) Terbinafine. An update of its use in superficial mycoses. Drugs, 58, pp. 179-202.
34. Loo, DS. (2006) Systemic antifungal agents: An update of established and new therapies. Adv Dermatol, 22, pp. 101-124.
35. Esterre, P., Inzan, CK and Ramarcel, ER. (2001) Treatment of chromoblastomycosis with terbinafine: Preliminary results of an open pilot study. Br J Dermatol, 134, pp. 33-36.
36. Sevigny, GM and Ramos-Caro, FA. (2000) Treatment of chromoblastomycosis due to Fonsecaea pedrosoi with low-dose terbinafine. Cutis, 66, pp. 45-46.
37. Bonifaz, A., Martínez-Soto, E. and Carrasco-Gerard, E. (1997) Treatment of chromoblastomycosis with itraconazole, cryosurgery, and a combination of both. Int J Dermatol, 36, pp. 542-547.
38. Bonifaz, A., Carrasco-Gerard, E. and Saul, A. (2001) Chromoblastomycosis: Clinical and mycologic experience of 51 cases. Mycoses, 44, pp. 1-7.
39. Gupta, AK, Taborda, PR and Sanzovo, AD. (2002) Alternate week and combination itraconazole and terbinafine therapy for chromoblastomycosis caused by Fonsecaea pedrosoi in Brazil. Med Mycol, 40, pp. 529-534.
40. Andrade, TS, Castro, LG and Nunes, RS (2004) Susceptibility of sequential Fonsecaea pedrosoi isolates from chromoblastomycosis patients to antifungal agents. Mycoses, 47, pp. 216-221.
41. Hardman, JG and Limbird, LE. (1996) Antimicrobial agents: Antifungal agents. Goodman and Gilman's: The Pharmacological Basis of Therapeutics, pp. 1175-1190. McGraw-Hill, New York
42. Odds, FC, Brown, AJ and Gow, NA. (2003) Antifungal agents: Mechanisms of action. Trends Microbiol, 11, pp. 272-279.