Poor performance associated with equine gastric ulceration syndrome in four Thoroughbred racehorses

Equine Veterinary Education

Volumn 20, Issue 3, 2008, Pages 119-124

  Franklin, S H ^a   Brazil, T J ^a   Allen, K J ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Equine gastric ulceration; Gastroscopy; Horse; Omeprazole; Performance; Racehorse

Indexed keywords

CONGIOPODIDAE; EQUIDAE;

EID: 40649111438     PISSN: 09577734     EISSN: None     Source Type: Journal    
DOI: 10.2746/095777308X282363     Document Type: Article

References (34)

1. Andrews, F.M., Sifferman, R.L., Bernard, W., Hughes, F.E., Holste, J.E., Daurio, C.P., Alva, R. and Cox, J.L. (1999) Efficacy of omeprazole paste in the treatment and prevention of gastric ulcers in horses. Equine vet. J., Suppl. 29, 81-86.
2. Anon (1999) The Equine Gastric Ulcer Council: Recommendations for the diagnosis and treatment of equine gastric ulcer syndrome (EGUS). Equine vet. Educ 11, 262-272.
3. Begg, L.M. and O'Sullivan, C.B. (2003) The prevalence and distribution of gastric ulceration in 345 racehorses. Aust. vet. J. 81, 199-201.
4. Bell, R.J.W., Kingston, J.K., Mogg, T.D. and Perkins, N.R. (2007) The prevalence of gastric ulceration in racehorses in New Zealand. N. Z. vet. J. 55, 13-18.
5. Borne, A.T. and MacAllister, C.G. (1993) Effect of sucralfate on healing of subclinical gastric ulcers in foals. J. Am. vet. med. Ass. 202, 1465-1468.
6. Chung, E.W., Ho, E.N.M., Leung, D.K.K., Tang, F.P.W., Yiu, K.C.H. and Wan, T.S.M. (2004) Detection of anti-ulcer drugs and their metabolites in horse urine by liquid chromatography - mass spectrometry. Chromatographia, Suppl. 59, S29-S38.
7. Collier, D.S. and Stoneham, S.J. (1997) Gastro-oesophageal ulceration in man and in horse: Semblance and dissemblance. Equine vet. J. 29, 410-412.
8. Daurio, C.P., Holste, J.E., Andrews, F.M., Merritt, A.M., Blackford, J.T., Dolz, F. and Thompson, D.R. (1999) Effect of omeprazole paste on gastric acid secretion in horses. Equine vet. J., Suppl. 29, 59-62.
9. Dionne, R.M., Vrins, A., Doucet, M.Y. and Pare, J. (2003) Gastric ulcers in Standardbred racehorses: prevalence, lesion description and risk factors. J. vet intern. Med. 17, 218-222.
10. Doucet, M.Y., Vrins, A.A., Dionne, R., Alva, R. and Ericsson, G. (2003) Efficacy of a paste formulation of omeprazole for the treatment of naturally occurring gastric ulcers in training Standardbred racehorses. Can. vet. J. 44, 581-585.
11. Hammond, C.J., Mason, D.K. and Watkins, K.L. (1988) Gastric ulceration in mature Thoroughbred horses. Equine vet. J. 18, 284-287.
12. Johnson, J.H., Vatistas, N., Castro, L., Fischer, T., Pipers, F.S. and Maye, D. (2001) Field survey of the prevalence of gastric ulcers in Thoroughbred racehorses and on response to treatment of affected horses with omeprazole. Equine vet. Educ. 13, 221-224.
13. Jensen, S.L. and Funch Jensen, P. (1992) Role of sucralfate in peptic disease. Dig. Dis. 10, 153-161.
14. Jonsson, H. and Egenvall, A. (2006) Prevalence of gastric ulceration in Swedish Standardbreds in race training. Equine vet. J. 38, 209-213.
15. Lane, J.G., Bladon, B., Little, D.R.M., Naylor, J.R.J., and Franklin, S.H. (2006) Dynamic obstructions of the equine upper respiratory tract Part 1: observations during high-speed treadmill endoscopy in 600 Thoroughbred racehorses. Equine vet. J. 38, 393-399.
16. Lester, G.D., Smith, R.L. and Robertson, I.D. (2005) Effects of treatment with omeprazole or ranitidine on gastric squamous ulceration in racing Thoroughbreds. J. Am. vet. med. Ass. 227, 1636-1639.
17. Martin, B.B. Jr., Reef, V.B., Parente, E.J. and Sage, A.D. (2000) Causes of poor performance of horses during training, racing, or showing: 348 cases (1992-1996). J. Am. vet. med. Ass. 216, 554-558.
18. MacAllister, C.G. (1999) A review of medical treatment for peptic ulcer disease. Equine vet. J., Suppl. 29, 45-49.
19. McClure, S.R., Glickman, L.T. and Glickman, N.W. (1999) Prevalence of gastric ulcers in show horses. J. Am. vet. med. Ass. 215, 1130-1133.
20. McClure, S.R., White, G.W., Sifferman, R.L., Bernard, W., Doucet, M.Y., Vrins, A., Holste, J.E., Fleishman, C., Alva, R. and Cramer, L.G. (2005) Efficacy of omeprazole paste for prevention of gastric ulcers in horses in race training. J. Am. vet. med. Ass. 226, 1681-1684.
21. McKeever, J.M., McKeever, K.H., Albeirci, J.M., Gordon, M.E. and Manso, H.C. (2006) Effect of omeprazole on markers of performance in gastric ulcer-free Standardbred horses. Equine vet. J., Suppl. 36, 668-671.
22. Merritt, A.M., Sanchez, L.C., Burrow, J.A., Church, M. and Ludzia, S. (2003) Effect of GastroGard and three compounded oral omeprazole preparations on 24h intragastric pH in gastrically canulated mature horses. Equine vet. J. 35, 691-695.
23. Morris, E.A. and Seeherman, H.J. (1991) Clinical evaluation of poor performance in the racehorse: the results of 275 evaluations. Equine vet. J. 23, 169-174.
24. Murray, M.J. (1991) The pathogenesis and prevalence of gastric ulceration in foals and horses. Vet. Med. 86, 815-819.
25. Murray, M.J. (1992) Gastric ulceration in horses - 91 cases (1987-1990). J. Am. vet. med. Ass. 201, 117-120.
26. Murray, M.J. and Schusser, G.F. (1993) Measurement of 24-h gastric pH using an indwelling pH electrode in horses unfed, fed and treated with ranitidine. Equine vet. J. 25, 417-421.
27. Murray, M.J. and Eichorn, E.S. (1996) Effects of intermittent feed deprivation, intermittent feed deprivation with ranitidine administration, and stall confinement with ad libitum access to hay on gastric ulceration in horses. Am. J. vet. Res. 57, 1599-1603.
28. Murray, M.J., Schusser, G.F., Pipers, R.S. and Gross, S.J. (1996) Factors associated with gastric lesions in Thoroughbred racehorses. Equine vet. J. 28, 368-374.
29. Murray, M.J., Grodinsky, C., Anderson, C.W., Radue, R.F. and Schmidt, G.R. (1989) Gastric ulcers in horses: a comparison of endoscopic findings in horses with and without clinical signs. Equine vet. J., Suppl. 7, 68-72.
30. Nadau J.A., Andrews F.M., Mathew A.G., Argenzio R.A., Blackford J.T., Sohtell M. and Saxton A.M. (2000) Evaluation of diet as a cause of gastric ulcers in horses. Am. J. vet. Res. 61, 784-790.
31. Orsini, J. (2000) Gastric ulceration in the mature horse: a review. Equine vet. Educ. 12, 24-27.
32. Orsini, J.A., Haddock, M., Stine, L., Sullivan, E.K., Rabuffo, T.S. and Smith, G. (2003) Odds of moderate or severe ulceration in racehorses receiving anti-ulcer medications. J. Am. vet. med. Ass. 223, 336-339.
33. Vatistas, N.J., Snyder, J.R., Carlson, G., Johnson, B., Arthur, R.M., Thurmond, M., Zhou, H. and Lloyd, K.L. (1999) Cross-sectional study of gastric ulcers of the squamous mucosa in Thoroughbred racehorses. Equine vet. J., Suppl. 29, 34-39.
34. White, G., McClure, S.R., Sifferman, R., Holste, J.E., Fleishman, C., Murray, M. and Cramer, L.G. (2007) Effects of short-term light to heavy exercise on gastric ulcer development in horses and efficacy of omeprazole paste in preventing gastric ulceration. J. Am. vet. med. Ass. 230, 1680-1682.