Upregulated expression of neuropeptide Y in hypothalamic-pituitary system of rats by chronic dexamethasone administration

Neuroscience Research

Volumn 60, Issue 3, 2008, Pages 259-265

  Konno, Jinko ^a   Yoshida, Sachine ^a   Ina, Ayuka ^a   Ohmomo, Hideki ^a   Shutoh, Fumihiro ^a   Nogami, Haruo ^a   Hisano, Setsuji ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Dexamethasone; Glucocorticoid; Hypothalamus; Median eminence; Neuropeptide Y; Pituitary

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; NEUROPEPTIDE Y; NEUROPHYSIN; NEUROPHYSIN 2; SESAME SEED OIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STAINING; UPREGULATION;

EID: 40649110036     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.11.005     Document Type: Article

References (37)

1. F.L. Bai M. Yamano Y. Shiotani P.C. Emson A.D. Smith J.F. Powess M. Tohyama An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat Brain Res. 331 1985 172 175
2. Y. Ben-Barak J.T. Russell M.H. Whitnall K. Ozato H. Gainer J. Neurosci. 5 1985 81 87
3. P. Ciofi G. Tramu D. Croix Coexistence of hGHRF and NPY immunoreactivities in neurons of the arcuate nucleus of the rat Neuroendocrinology 45 1987 425 428
4. P. Ciofi J.H. Fallon D. Criox J.M. Polak G. Tramu Expression of neuropeptide Y precursor-immunoreactivity in the hypothalamic dopaminergic tubero-infundibular system during lactation in rodents Endocrinology 128 1991 823 834
5. R. Corder F. Pralong D. Turnill P. Saudan A.F. Miller R.C. Gaillard Dexamethasone treatment increases neuropeptide Y levels in rat hypothalamic neurones Life Sci. 43 1988 1879 1886
6. E.L. Dimitrov M.R. DeJoseph M.S. Brownfield J.H. Urban Involvement of neuropeptide Y Y1 receptors in the regulation of neuroendocrine corticotropin-releasing hormone neuronal activity Endocrinology 148 2007 3666 3673
7. C.F. Elias C.B. Saper E. Maratos-Flier N.A. Tritos C. Lee J. Kelly J.B. Tatro G.E. Hoffman M.M. Ollmann G.S. Barsh T. Sakurai M. Yanagisawa J.K. Elmquist Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area J. Comp. Neurol. 402 1998 442 459
8. T. Füzesi G. Wittmann Z. Liposits R.M. Lechan C. Fekete Contribution of noradrenergic and adrenergic cell groups of the brainstem and agouti-related protein (AGRP)-synthesizing neurons of the arcuate nucleus to neuropeptide-Y innervation of corticotropin-releasing hormone neurons in hypothalamic paraventricular nucleus of the rat Endocrinology 148 2007 5442 5450
9. M. Goto H. Arima M. Watanabe M. Hayashi R. Banno I. Sato H. Nagasaki Y. Oiso Ghrelin increases neuropeptide Y and agouti-related peptide gene expression in the arcuate nucleus in rat hypothalamic organotypic cultures Endocrinology 147 2006 5102 5109
10. K.L. Grove R.S. Brogan M.S. Smith Novel expression of neuropeptide Y (NPY) mRNA in hypothalamic regions during development: region-specific effects of maternal deprivation on NPY and agouti-related protein mRNA Endocrinology 142 2001 4771 4776
11. T.M. Hahn J.F. Breininger D.G. Baskin M.W. Schwartz Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons Nat. Neurosci. 4 1998 271 272
12. C. Haskell-Luevano P. Chen C. Li K. Chang M.S. Smith J.L. Cameron R.D. Cone Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat Endocrinology 140 1999 1408 1415
13. S. Hisano Y. Tsuruo S. Katoh S. Daikoku N. Yanaihara T. Shibasaki Intragranular colocalization of arginine vasopressin and methionine-enkephalin-octapeptide in CRF-axons in the rat median eminence Cell Tissue Res. 249 1987 497 507
14. S. Hisano M. Chikamori-Aoyama S. Katoh Y. Kagotani S. Daikoku K. Chihara Suprachiasmatic nucleus neurons immunoreactive for vasoactive intestinal polypeptide have synaptic contacts with axons immunoreactive for neuropeptide Y: an immunoelectron microscopic study in the rat Neurosci. Lett. 88 1988 145 150
15. S. Hisano Y. Kagotani Y. Tsuruo S. Daikoku K. Chihara M.H. Whitnall Localization of glucocorticoid receptor in neuropeptide Y-containing neurons in the arcuate nucleus of the rat hypothalamus Neurosci. Lett. 95 1988 13 18
16. S. Hisano Y. Fukui M. Chikamori-Aoyama T. Aizawa T. Shibasaki Reciprocal synaptic relations between CRF-immunoreactive- and TRH-immunoreactive neurons in the paraventricular nucleus of the rat hypothalamus. Brain Res. 620 1993 343 346
17. A. Ina M. Sugiyama J. Konno S. Yoshida H. Ohmomo H. Nogami F. Shutoh S. Hisano Cajal–Retzius cells and subplate neurons differentially express vesicular glutamate transporter 1 and 2 during development of mouse cortex Eur. J. Neurosci. 26 2007 615 623
18. H. Jamal P.M. Jones J. Byrne K. Suda M.A. Ghatei S.M. Kanse S.R. Bloom Peptide contents of neuropeptide Y, vasoactive intestinal polypeptide, and β-calcitonin gene-related peptide and their messenger ribonucleic acids after dexamethasone treatment in the isolated rat islets of Langerhans Endocrinology 129 1991 3372 3380
19. P.M. Jones M.A. Ghatei J. Steel D. O’Halloran G. Gon S. Legon J.M. Burrin U. Leonhardt J.M. Polak S.R. Bloom Evidence for neuropeptide Y synthesis in the rat anterior pituitary and the influence of thyroid hormone status: comparison with vasoactive intestinal peptide, substance P, and neurotensin Endocrinology 125 1989 334 341
20. A.M. Karssen O.C. Meijer A. Berry R.S. Piñol E.R. de Kloet Low doses of dexamethasone can produce a hypocorticosteroid state in the brain Endocrinology 146 2005 5587 5595
21. M. Kawano A. Kawasaki H. Sakata-Haga Y. Fukui H. Kawano H. Nogami S. Hisano Particular subpopulations of midbrain and hypothalamic dopamine neurons express vesicular glutamate transporter 2 in the rat brain J. Comp. Neurol. 498 2006 581 592
22. A. Kawasaki K. Hoshi M. Kawano H. Nogami H. Yoshikawa S. Hisano Up-regulation of VGLUT2 expression in hypothalamic-neurohypophysial neurons of the rat following osmotic challenge Eur. J. Neurosci. 22 2005 672 680
23. J.I. Koenig Regulation of the hypothalamo–pituitary axis by neuropeptide Y Ann. NY Acad. Sci. 611 1990 317 328
24. R.M. Lechan J.L. Nestler S. Jacobson The tuberoinfundibular system of the rat as demonstrated by immunocytochemical localization of retrogradely transported wheat germ agglutinin (WGA) from the median eminence. Brain Res. 245 1982 1 15
25. C. Li P. Chen S.M. Smith Morphological evidence for direct interaction between arcuate nucleus neuropeptide Y (NPY) neurons and gonadotropin-releasing hormone neurons and the possible involvement of NPY Y1 receptors Endocrinology 140 1999 5382 5390
26. X.-M. Ma G. Aguilera Differential regulation of corticotropin-releasing hormone and vasopressin transcription by glucocorticoids Endocrinology 140 1999 5642 5650
27. J.K. McDonald M.D. Lumpkin W.K. Samson S.M. McCann Neuropeptide Y affects secretion of luteinizing hormone and growth hormone in ovariectomized rats Proc. Natl. Acad. Sci. U.S.A. 82 1985 561 564
28. J.K. McDonald J.I. Koenig D.M. Gibbs P. Collins B.D. Noe High concentrations of neuropeptide Y in pituitary portal blood in rats Neuroendocrinology 46 1987 538 541
29. U. Myrsén B. Ahrén F. Sundler Neuropeptide Y is expressed in subpopulations of insulin- and non-insulin-producing islet cells in the rat after dexamethasone treatment: a combined immunocytochemical and in situ hybridization study Regul. Pept. 60 1995 18 31
30. H. Nogami T. Takeuchi Increased population of nonhormone-producing cells suggests the presence of dysfunctional growth hormone cells in the anterior pituitary gland of the spontaneous dwarf rat Neuroendocrinology 57 1993 374 380
31. M. Park K. Wakabayashi Preparation of a monoclonal antibody to common amino acid sequence of LHRH and its application Endocr. Jpn. 33 1986 257 272
32. I. Sato H. Arima N. Ozaki M. Watanabe M. Goto M. Hayashi R. Banno H. Nagasaki Y. Oiso Insulin inhibits neuropeptide Y gene expression in the arcuate nucleus through GABAergic systems J. Neurosci. 25 2005 8657 8664
33. E. Spinedi R.C. Gaillard A regulatory loop between the hypothalamo–pituitary–adrenal (HPA) axis and circulating leptin: a physiological role of ACTH Endocrinology 139 1998 4016 4020
34. S. Stanley K. Wynne B. McGowan S. Bloom Hormonal regulation of food intake Physiol. Rev. 85 2005 1131 1158
35. C. Wahlestedt G. Skagerberg R. Ekman M. Heilig F. Sundler R. Hakanson Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary–adrenocortical axis in the rat Brain Res. 417 1987 33 38
36. B.D. White R.G. Dean R.J. Martin Adrenalectomy decreases neuropeptide Y mRNA levels in the arcuate nucleus Brain Res. Bull. 25 1990 711 715
37. J.P.H. Wilding S.G. Gilbey P.D. Lambert M.A. Ghatei S.R. Bloom Increase in neuropeptide Y content and gene expression in the hypothalamus of rats treated with dexamethasone are prevented by insulin Neuroendocrinology 57 1993 581 587