Second Stem Cell Transplantation in Patients with Fanconi Anemia Using Antithymocyte Globulin Alone for Conditioning

Biology of Blood and Marrow Transplantation

Volumn 14, Issue 4, 2008, Pages 445-448

  Ayas, Mouhab ^a   Al Jefri, Abdullah ^a   Al Seraihi, Amal ^a   Al Mahr, Mohammed ^a   Al Ahmari, Ali ^a   El Solh, Hassan ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

Antithymocyte globulins; Fanconi anemia; Graft failure; Second stem cell transplantation

Indexed keywords

CD34 ANTIGEN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; GRANULOCYTE COLONY STIMULATING FACTOR; HLA ANTIGEN; THYMOCYTE ANTIBODY;

ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; BLOOD TRANSFUSION; CASE REPORT; DISEASE FREE SURVIVAL; ENGRAFTMENT; FANCONI ANEMIA; FEMALE; FOLLOW UP; GRAFT FAILURE; GRAFT SURVIVAL; GRAFT VERSUS HOST REACTION; HLA MATCHING; HUMAN; MALE; THROMBOCYTE TRANSFUSION; TREATMENT FAILURE; TREATMENT OUTCOME;

ANTILYMPHOCYTE SERUM; CYCLOPHOSPHAMIDE; DRUG THERAPY, COMBINATION; FANCONI ANEMIA; HUMANS; IMMUNOSUPPRESSIVE AGENTS; RETREATMENT; RETROSPECTIVE STUDIES; STEM CELL TRANSPLANTATION; TIME FACTORS; TRANSPLANTATION CHIMERA; TRANSPLANTATION CONDITIONING; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 40649103914     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2008.02.004     Document Type: Article

References (22)

1. Gluckman E. Allogeneic bone marrow transplantation in Fanconi anemia. Bone Marrow Transplant 18 (1996) S33-S35
2. Bonfim C.M., de Medeiros C.R., Bitencourt M.A., et al. HLA-matched related donor hematopoietic cell transplantation in 43 patients with Fanconi anemia conditioned with 60 mg/kg of cyclophosphamide. Biol Blood Marrow Transplant 13 (2007) 1455-1460
3. Tan P.L., Wagner J.E., Auerbach A.D., Defor T.E., Slungaard A., and Macmillan M.L. Successful engraftment without radiation after fludarabine-based regimen in Fanconi anemia patients undergoing genotypically identical donor hematopoietic cell transplantation. Pediatr Blood Cancer 46 (2006) 630-636
4. Socié G., Devergie A., Girinski T., et al. Transplantation for Fanconi's anaemia: long-term follow-up of fifty patients transplanted from a sibling donor after low-dose cyclophosphamide and thoraco-abdominal irradiation for conditioning. Br J Haematol 103 (1998) 249-255
5. Farzin A., Davies S.M., Smith F.O., et al. Matched sibling donor haematopoietic stem cell transplantation in Fanconi anaemia: an update of the Cincinnati Children's experience. Br J Haematol 136 (2007) 633-640
6. Bitan M., Or R., Shapira M.Y., et al. Fludarabine-based reduced intensity conditioning for stem cell transplantation of Fanconi anemia patients from fully matched related and unrelated donor. Biol Blood Marrow Transplant 12 (2006) 712-718
7. Motwani J., Lawson S.E., and Darbyshire P.J. Successful HSCT using nonradiotherapy-based conditioning regimens and alternative donors in patients with Fanconi anaemia-experience in a single UK centre. Bone Marrow Transplant 5 (2005) 405-410
8. Ayas M., Al-Jefri A., Al-Seraihi A., et al. Allogeneic stem cell transplantation in Fanconi anemia patients presenting with myelodysplasia and/or clonal abnormality: update on the Saudi experience. Bone Marrow Transplant 41 (2008) 261-265
9. Ayas M., Al-Jefri A., Al-Mahr M., et al. Stem cell transplantation for patients with Fanconi anemia with low-dose cyclophosphamide and antithymocyte globulins without the use of radiation therapy. Bone Marrow Transplant 35 (2005) 463-466
10. Ayas M., Solh H., Mustafa M.M., et al. Bone marrow transplantation from matched siblings in patients with fanconi anemia utilizing low-dose cyclophosphamide, thoracoabdominal radiation and antithymocyte globulin. Bone Marrow Transplant 27 (2001) 139-143
11. Wolff S.N. Second hematopoietic stem cell transplantation for the treatment of graft failure, graft rejection or relapse after allogeneic transplantation. Bone Marrow Transplant 29 (2002) 545-552
12. Weisdorf D.J., Verfaillie C.M., Davies S.M., et al. Hematopoietic growth factors for graft failure after bone marrow transplantation: a randomized trial of granulocyte-macrophage colony-stimulating factor (GM-CSF) versus sequential GM-CSF plus granulocyte-CSF. Blood 85 (1995) 3452-3456
13. Davies S.M., Weisdorf D.J., Haake R.J., et al. Second infusion of bone marrow for treatment of graft failure after allogeneic bone marrow transplantation. Bone Marrow Transplant 14 (1994) 73-77
14. McCann S.R., Bacigalupo A., Gluckman E., et al. Graft rejection and second bone marrow transplants for acquired aplastic anaemia: a report from the Aplastic Anaemia Working Party of the European Bone Marrow Transplant Group. Bone Marrow Transplant 13 (1994) 233-237
15. Champlin R.E., Horowitz M.M., van Bekkum D.W., et al. Graft failure following bone marrow transplantation for severe aplastic anemia: risk factors and treatment results. Blood 73 (1989) 606-613
16. Gluckman E., Rocha V., Ionescu I., et al. Results of unrelated cord blood transplant in Fanconi anemia patients: risk factor analysis for engraftment and survival. Biol Blood Marrow Transplant 13 (2007) 1073-1082
17. Wagner J.E., Eapen M., MacMillan M.L., et al. Unrelated donor bone marrow transplantation for the treatment of Fanconi anemia. Blood 109 (2007) 2256-2262
18. Hill R.S., Petersen F.B., Storb R., et al. Mixed hematologic chimerism after allogeneic marrow transplantation for severe aplastic anemia is associated with a higher risk of graft rejection and a lessened incidence of acute graft-versus-host disease. Blood 67 (1986) 811-816
19. Stucki A., Leisenring W., Sandmaier B.M., Sanders J., Anasetti C., and Storb R. Decreased rejection and improved survival of first and second marrow transplants for severe aplastic anemia (a 26-year retrospective analysis). Blood 92 (1998) 2742-2749
20. Grandage V.L., Cornish J.M., Pamphilon D.H., et al. Second allogeneic bone marrow transplants from unrelated donors for graft failure following initial unrelated donor bone marrow transplantation. Bone Marrow Transplant 21 (1998) 687-690
21. Guardiola P., Kuentz M., Garban F., et al. Second early allogeneic stem cell transplantations for graft failure in acute leukaemia, chronic myeloid leukaemia and aplastic anaemia. French Society of Bone Marrow Transplantation. Br J Haematol 111 (2000) 292-302
22. Mrsíc M., Horowitz M.M., Atkinson K., et al. Second HLA-identical sibling transplants for leukemia recurrence. Bone Marrow Transplant 9 (1992) 269-275