Effectiveness of co-artemether in an unsupervised outpatient setting for the treatment of falciparum malaria

Travel Medicine and Infectious Disease

Volumn 6, Issue 1-2, 2008, Pages 29-31

  Toovey, S ^a  

^a SAA Netcare Travel Clinics   (South Africa)

Author keywords

Artemether lumefantrine; Artemisinin combination therapy; Falciparum; Late treatment failure; Malaria

Indexed keywords

ARTEMETHER PLUS BENFLUMETOL;

ABSENCE OF SIDE EFFECTS; ADULT; AFRICA; ARTICLE; BLOOD SMEAR; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG TREATMENT FAILURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MOZAMBIQUE; OPEN STUDY; OUTPATIENT CARE; PRIORITY JOURNAL; PROSPECTIVE STUDY;

EID: 40649096381     PISSN: 14778939     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tmaid.2007.08.007     Document Type: Article

References (8)

1. C. Hatz S. Abdulla R. Mull D. Schellenberg I. Gathmann P. Kibatala Efficacy and safety of CGP 56697 (artemether and benflumetol) compared with chloroquine to treat acute falciparum malaria in Tanzanian children aged 1–5 years Trop Med Int Health 3 6 1998 498 504
2. R.D. Newman M.E. Parise L. Slutsker B. Nahlen R.W. Steketee Safety, efficacy and determinants of effectiveness of antimalarial drugs during pregnancy: implications for prevention programmes in Plasmodium falciparum -endemic sub-Saharan Africa Trop Med Int Health 8 6 2003 488 506
3. S.L. von S. Jaffar M. Pinder M. Haywood G. Snounou B. Gemperli Treatment of African children with uncomplicated falciparum malaria with a new antimalarial drug, CGP 56697 J Infect Dis 176 4 1997 1113 1116
4. F. Checchi P. Piola C. Fogg F. Bajunirwe S. Biraro F. Grandesso Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda Malar J 5 2006 59
5. C. Fogg F. Bajunirwe P. Piola S. Biraro F. Checchi J. Kiguli Adherence to a six-dose regimen of artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Uganda Am J Trop Med Hyg 71 5 2004 525 530
6. P. Piola C. Fogg F. Bajunirwe S. Biraro F. Grandesso E. Ruzagira Supervised versus unsupervised intake of six-dose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial Lancet 365 9469 2005 1467 1473
7. F. Ezzet R. Mull J. Karbwang Population pharmacokinetics and therapeutic response of CGP 56697 (artemether+benflumetol) in malaria patients Br J Clin Pharmacol 46 6 1998 553 561
8. F. Ezzet V.M. van F. Nosten S. Looareesuwan N.J. White Pharmacokinetics and pharmacodynamics of lumefantrine (benflumetol) in acute falciparum malaria Antimicrob Agents Chemother 44 3 2000 697 704