Generation of fusion proteins for selective occlusion of tumor vessels

Current Drug Discovery Technologies

Volumn 5, Issue 1, 2008, Pages 1-8

  Kessler, Torsten ^a   Schwöppe, Christian ^a   Liersch, Ruediger ^a   Schliemann, Christoph ^a,c   Hintelmann, Heike ^a   Bieker, Ralf ^a   Berdel, Wolfgang E ^a,b   Mesters, Rolf M ^a,b  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c ETH ZURICH   (Switzerland)

Author keywords

Fusion proteins; Truncated tissue factor; Tumor targeting

Indexed keywords

CD51 ANTIGEN; HYBRID PROTEIN; MICROSOMAL AMINOPEPTIDASE; PEPTIDE DERIVATIVE; THROMBOPLASTIN; TISSUE FACTOR NGR; TISSUE FACTOR RGD; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BLOOD CLOTTING; BREAST ADENOCARCINOMA; CLINICAL STUDY; CONTROLLED STUDY; ENDOTHELIUM CELL; ESCHERICHIA COLI; HISTOLOGY; IMMUNOBLOTTING; IN VIVO STUDY; MALE; MASS SPECTROMETRY; MELANOMA; MOUSE; NONHUMAN; NUDE MOUSE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SCALE UP; SCREENING; THROMBOGENICITY; THROMBOSIS; TUMOR GROWTH;

ADENOCARCINOMA; ANGIOGENESIS INHIBITORS; ANIMALS; BASE SEQUENCE; BREAST NEOPLASMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOTHELIAL CELLS; FACTOR X; FEMALE; HUMANS; INTEGRIN ALPHAVBETA3; INTEGRINS; MELANOMA, EXPERIMENTAL; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; RECEPTORS, VITRONECTIN; RECOMBINANT FUSION PROTEINS; REGIONAL BLOOD FLOW; STREPTAVIDIN;

EID: 40549111932     PISSN: 15701638     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016308783769487     Document Type: Article

References (37)