메뉴 건너뛰기




Volumn 37, Issue 4, 2006, Pages 294-301

Hepatoprotective activities of gomisin A and gomisin N

Author keywords

Gomisin A; Gomisin N; Hepatoprotective activity; Schizandrae fructus

Indexed keywords


EID: 40549111410     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (24)
  • 1
    • 0003462408 scopus 로고
    • China-English Manual of common-used in traditional Chinenese Medicine
    • Guangzhou
    • Ou, M. (1992) China-English Manual of common-used in traditional Chinenese Medicine. Guangdong Science and Technology Press: Guangzhou 69-70.
    • (1992) Guangdong Science and Technology Press , pp. 69-70
    • Ou, M.1
  • 3
    • 0025226535 scopus 로고
    • Antioxidative effects of three components isolated from fruit of Schizandra
    • Huang, Y. S., He, Y. and Zhang, J. T. (1990) Antioxidative effects of three components isolated from fruit of Schizandra. Chinese J. Pharmacol, Toxicol. 4: 275-277.
    • (1990) Chinese J. Pharmacol, Toxicol , vol.4 , pp. 275-277
    • Huang, Y.S.1    He, Y.2    Zhang, J.T.3
  • 4
    • 0002214754 scopus 로고    scopus 로고
    • Antimicrobial effects of Schizandra chinensis extract on pathogenetic microorganism
    • Lee, S. H. and Lim, Y. S. (1998) Antimicrobial effects of Schizandra chinensis extract on pathogenetic microorganism. Kor. J. Food Sci. Nutr. 27: 239-243.
    • (1998) Kor. J. Food Sci. Nutr , vol.27 , pp. 239-243
    • Lee, S.H.1    Lim, Y.S.2
  • 5
    • 0023268618 scopus 로고    scopus 로고
    • Ohkura, Y., Mizoguchi, Y., Yamamoto, S. and Morisawara, S. (1987) Inhibitory effect of TJN-101 ((+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12- tetramethoxy-6,7-dimethyl-l 0,11-methylenedioxy-6-dibenzo [a,c] cyclooctenol) on immuno logically induced liver injuries. Jpn. J. Pharmacol. 44: 179-185.
    • Ohkura, Y., Mizoguchi, Y., Yamamoto, S. and Morisawara, S. (1987) Inhibitory effect of TJN-101 ((+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12- tetramethoxy-6,7-dimethyl-l 0,11-methylenedioxy-6-dibenzo [a,c] cyclooctenol) on immuno logically induced liver injuries. Jpn. J. Pharmacol. 44: 179-185.
  • 6
    • 0027240206 scopus 로고
    • Preventive effect of gomisin A, a lignan component of shizandra fruits, on acetaminophen-induced hepatotoxicity in rats
    • Yamada, S., Murawaki, Y. and Kawasaki, H. (1993) Preventive effect of gomisin A, a lignan component of shizandra fruits, on acetaminophen-induced hepatotoxicity in rats. Biochem. Pharmacol. 46: 1081-1085.
    • (1993) Biochem. Pharmacol , vol.46 , pp. 1081-1085
    • Yamada, S.1    Murawaki, Y.2    Kawasaki, H.3
  • 7
    • 0024946962 scopus 로고
    • Pharmacological action and clinical use of fructus schizandrae
    • Liu, G. T. (1989) Pharmacological action and clinical use of fructus schizandrae. Chin. Med. J. 46: 740-749.
    • (1989) Chin. Med. J , vol.46 , pp. 740-749
    • Liu, G.T.1
  • 8
    • 0026096606 scopus 로고
    • Effect of dibenzo[a,c]cyclooctene lignans isolated from Fructus Schizandrae on lipid peroxidation and anti-oxidative enzyme activity
    • Lu, H. and Liu, G. T. (1991) Effect of dibenzo[a,c]cyclooctene lignans isolated from Fructus Schizandrae on lipid peroxidation and anti-oxidative enzyme activity. Chem. Biol. Interact. 78: 77-84.
    • (1991) Chem. Biol. Interact , vol.78 , pp. 77-84
    • Lu, H.1    Liu, G.T.2
  • 9
    • 0020031966 scopus 로고
    • Phannacological properties of dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. I. Interaction with rat liver cytochrome P-450 and inhibition of xenobiotic metabolism and mutagenicity
    • Liu, K. T. and Lesca, P. (1982) Phannacological properties of dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae chinensis. I. Interaction with rat liver cytochrome P-450 and inhibition of xenobiotic metabolism and mutagenicity. Chem. Biol. Interact. 3: 301-314.
    • (1982) Chem. Biol. Interact , vol.3 , pp. 301-314
    • Liu, K.T.1    Lesca, P.2
  • 10
    • 0028069793 scopus 로고
    • Inhibition by gomisin A, a lignan compound, of hepatocarcinogenesis by 3′-methyl-4-dimethylaminoazobenzene in rats
    • Ohtaki, Y., Nomura, M., Hida, T., Miyamoto, K., Kanitani, M., Aizawa, T. and Aburada, M. (1994) Inhibition by gomisin A, a lignan compound, of hepatocarcinogenesis by 3′-methyl-4-dimethylaminoazobenzene in rats. Biol, Pharm. Bull. 6: 808-814.
    • (1994) Biol, Pharm. Bull , vol.6 , pp. 808-814
    • Ohtaki, Y.1    Nomura, M.2    Hida, T.3    Miyamoto, K.4    Kanitani, M.5    Aizawa, T.6    Aburada, M.7
  • 11
    • 0029772110 scopus 로고    scopus 로고
    • Effects of Schisandrin B and alpha-tocopherol on lipid peroxidation, in vitro and in vivo
    • Mak, D., H., Ip, S. P., Li, P. C., Poon, M. K. and Ko, K. M. (1996) Effects of Schisandrin B and alpha-tocopherol on lipid peroxidation, in vitro and in vivo. Mol. Cell. Biochem. 2: 161-165.
    • (1996) Mol. Cell. Biochem , vol.2 , pp. 161-165
    • Mak, D.H.1    Ip, S.P.2    Li, P.C.3    Poon, M.K.4    Ko, K.M.5
  • 12
    • 0024540083 scopus 로고
    • Mechanism of carbon tetrachloride hepatotoxicity
    • Clawson, G. A. (1989) Mechanism of carbon tetrachloride hepatotoxicity. Pathol. Immunopathol. Res. 8: 104-112.
    • (1989) Pathol. Immunopathol. Res , vol.8 , pp. 104-112
    • Clawson, G.A.1
  • 14
    • 0002929182 scopus 로고
    • Hydroxy-alkenals; cytotoxic products of lipidperoxidation
    • Esterbauer, H., Zollner, H. and Schur, R. J. (1988) Hydroxy-alkenals; cytotoxic products of lipidperoxidation. Science Biochem. 1: 311-319.
    • (1988) Science Biochem , vol.1 , pp. 311-319
    • Esterbauer, H.1    Zollner, H.2    Schur, R.J.3
  • 15
    • 0026552871 scopus 로고
    • Determination of malonaldehyde-modified 2′-deoxyguanosine-3′-monophosphate and DNA by 32P-postlabelling
    • Vaca, C. E., Vodicka, P. and Hemminki, K. (1992) Determination of malonaldehyde-modified 2′-deoxyguanosine-3′-monophosphate and DNA by 32P-postlabelling. Carcinogenesis 13: 593-599.
    • (1992) Carcinogenesis , vol.13 , pp. 593-599
    • Vaca, C.E.1    Vodicka, P.2    Hemminki, K.3
  • 16
    • 0036354025 scopus 로고    scopus 로고
    • Effects of anti-ulcer agents on ethanol-induced gastric mucosal lesions in D-galactosamine-induced hepatitis rats
    • Taniguchi, H., Yomota, E., Nogi, K. and Onoda, Y. (2002) Effects of anti-ulcer agents on ethanol-induced gastric mucosal lesions in D-galactosamine-induced hepatitis rats. Arzneimittelforschung 52: 600-604.
    • (2002) Arzneimittelforschung , vol.52 , pp. 600-604
    • Taniguchi, H.1    Yomota, E.2    Nogi, K.3    Onoda, Y.4
  • 17
    • 85007956684 scopus 로고    scopus 로고
    • Ikeya, Y., Taguchi, H., Yosioka. I. and Kobayashi H. (1979) The constituents of Schizandra chinensis Baill. V. The structures of four new lignans, gomisin N, gomisin O, epigomisin O and gomisin E, and transformation of gomisin N to deangeloylgomisin B. Chem. Pharm. Bull. 27: 2695-2709.
    • Ikeya, Y., Taguchi, H., Yosioka. I. and Kobayashi H. (1979) The constituents of Schizandra chinensis Baill. V. The structures of four new lignans, gomisin N, gomisin O, epigomisin O and gomisin E, and transformation of gomisin N to deangeloylgomisin B. Chem. Pharm. Bull. 27: 2695-2709.
  • 18
    • 0018365049 scopus 로고    scopus 로고
    • Ikeya, Y., Taguchi, H., Yosioka, I. and Kobayashi, H. (1979) The constituents of Schiscmdra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin. Chem. Pharm. Bull. 27: 1383-1394.
    • Ikeya, Y., Taguchi, H., Yosioka, I. and Kobayashi, H. (1979) The constituents of Schiscmdra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin. Chem. Pharm. Bull. 27: 1383-1394.
  • 19
    • 0014645531 scopus 로고
    • High-yield preparation of isolated rat liver parenchymal cells: A biochemical and fine structural study
    • Berry, M. N. and Friend, D. S. (1969) High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study. J. Cell Biol. 43: 506-520.
    • (1969) J. Cell Biol , vol.43 , pp. 506-520
    • Berry, M.N.1    Friend, D.S.2
  • 20
    • 0018356117 scopus 로고
    • Preparation of collagen substrates for cell attachment: Effect of collagen concentration and phosphate buffer
    • Kleinman, H. K., McGoodwin, E. B., Rennard, S. I. and Martin, G. R. (1979) Preparation of collagen substrates for cell attachment: effect of collagen concentration and phosphate buffer. Anal. Biochem. 94: 308-312.
    • (1979) Anal. Biochem , vol.94 , pp. 308-312
    • Kleinman, H.K.1    McGoodwin, E.B.2    Rennard, S.I.3    Martin, G.R.4
  • 21
    • 0021079631 scopus 로고
    • Assay method for antihepatotoxic activity using carbon tetrachloride induced cytotoxicity in primary cultured hepatocytes
    • Kiso, Y., Tohkin, M. and Hikino, H. (1983) Assay method for antihepatotoxic activity using carbon tetrachloride induced cytotoxicity in primary cultured hepatocytes. Planta Med. 49: 222-225.
    • (1983) Planta Med , vol.49 , pp. 222-225
    • Kiso, Y.1    Tohkin, M.2    Hikino, H.3
  • 22
    • 0030583290 scopus 로고    scopus 로고
    • Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes
    • Tseng, T. H., Wang, C. J., Kao, E. S. and Chu, H. Y. (1996) Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes. Chem. Biol. Interact. 101: 137-148.
    • (1996) Chem. Biol. Interact , vol.101 , pp. 137-148
    • Tseng, T.H.1    Wang, C.J.2    Kao, E.S.3    Chu, H.Y.4
  • 23
    • 0021049324 scopus 로고
    • Assay method for antihepatotoxic activity using galactosamine-induced cytotoxicity in primary-cultured hepatocytes
    • Kiso, Y., Tohkin, M. and Hikino, H. (1983) Assay method for antihepatotoxic activity using galactosamine-induced cytotoxicity in primary-cultured hepatocytes. J. Nat. Prod. 46: 841-847.
    • (1983) J. Nat. Prod , vol.46 , pp. 841-847
    • Kiso, Y.1    Tohkin, M.2    Hikino, H.3
  • 24
    • 0023028709 scopus 로고
    • 4 and release of a sequestered calcium pool
    • 4 and release of a sequestered calcium pool. Biochem. Pharmacol. 35, 4131-4137.
    • (1986) Biochem. Pharmacol , vol.35 , pp. 4131-4137
    • Long, R.M.1    Moore, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.