Increased therapeutic efficacy of the prostate-specific oncolytic adenovirus Ad[I/PPT-E1A] by reduction of the insulator size and introduction of the full-length E3 region

Cancer Gene Therapy

Volumn 15, Issue 4, 2008, Pages 203-213

  Danielsson, A ^a   Dzojic, H ^a   Nilsson, B ^a   Essand, M ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Adenovirus E3 region; Bioluminescence imaging; Oncolytic adenovirus; Prostate specific promoter

Indexed keywords

ADENOVIRUS DEATH PROTEIN; E1A PROTEIN; LUCIFERASE; ONCOLYTIC ADENOVIRUS; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; BIOASSAY; CANCER INHIBITION; CELL SPECIFICITY; CONTROLLED STUDY; CYTOLYSIS; CYTOPATHOGENIC EFFECT; DRUG EFFICACY; DRUG SPECIFICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULATOR ELEMENT; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE; PROSTATE TUMOR; REPORTER GENE; VIRUS GENOME; VIRUS REPLICATION;

ADENOCARCINOMA; ADENOVIRUS E1A PROTEINS; BASE SEQUENCE; CELL LINE, TUMOR; DNA PRIMERS; GENETIC VECTORS; HUMANS; MALE; PROMOTER REGIONS (GENETICS); PROSTATIC NEOPLASMS;

ADENOVIRIDAE;

EID: 40549092679     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/sj.cgt.7701117     Document Type: Article

References (28)